Zobrazeno 1 - 10
of 21
pro vyhledávání: '"antibody germline"'
Autor:
Aleman, Fernando, Tzarum, Netanel, Kong, Leopold, Nagy, Kenna, Zhu, Jiang, Wilson, Ian A., Law, Mansun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jul . 115(29), 7569-7574.
Externí odkaz:
https://www.jstor.org/stable/26510979
Publikováno v:
Stem Cell Research, Vol 50, Iss , Pp 102125- (2021)
SARS-CoV-2 causing the worldwide pandemic has changed people’s life in multiple aspects dramatically since it’s first identified in Wuhan, China at the end of 2019. While the numbers of infected patients and death toll keep vigorous increasing, c
Externí odkaz:
https://doaj.org/article/ae6097233f1e446a877cee7e31016e2a
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
B cells produce antibodies, key effector molecules in health and disease. They mature their properties, including their affinity for antigen, through hypermutation events; processes that involve, e.g., base substitution, codon insertion and deletion,
Externí odkaz:
https://doaj.org/article/13e5e21a985c4c4d9fa9aa9382f4bb07
Autor:
Ariadna Grinyo, Elias H. Augestad, Mayda Hernandez, Netanel Tzarum, Kenna Nagy, Robyn L. Stanfield, Linling He, Mansun Law, Robert E. Lanford, Rodrigo Velázquez-Moctezuma, Deborah Chavez, Xiaohe Lin, Jens Bukh, Erick Giang, Ian A. Wilson, Mallorie E. Fouch, Jannick Prentoe, Benjamin J. Doranz, Jiang Zhu, Fang Chen
Publikováno v:
Immunity
Chen, F, Tzarum, N, Lin, X, Giang, E, Velázquez-Moctezuma, R, Augestad, E H, Nagy, K, He, L, Hernandez, M, Fouch, M E, Grinyó, A, Chavez, D, Doranz, B J, Prentoe, J, Stanfield, R L, Lanford, R, Bukh, J, Wilson, I A, Zhu, J & Law, M 2021, ' Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins ', Immunity, vol. 54, no. 4, pp. 781-796.e4 . https://doi.org/10.1016/j.immuni.2021.02.013
Chen, F, Tzarum, N, Lin, X, Giang, E, Velázquez-Moctezuma, R, Augestad, E H, Nagy, K, He, L, Hernandez, M, Fouch, M E, Grinyó, A, Chavez, D, Doranz, B J, Prentoe, J, Stanfield, R L, Lanford, R, Bukh, J, Wilson, I A, Zhu, J & Law, M 2021, ' Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins ', Immunity, vol. 54, no. 4, pp. 781-796.e4 . https://doi.org/10.1016/j.immuni.2021.02.013
Human IGHV1-69-encoded broadly neutralizing antibodies (bnAbs) that target the hepatitis C virus (HCV) envelope glycoprotein (Env) E2 are important for protection against HCV infection. An IGHV1-69 ortholog gene, VH1.36, is preferentially used for bn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9b240bcbc75d463054a656be6471f1
https://europepmc.org/articles/PMC8046733/
https://europepmc.org/articles/PMC8046733/
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Stem Cell Research
Stem Cell Research, Vol 50, Iss, Pp 102125-(2021)
Stem Cell Research, Vol 50, Iss, Pp 102125-(2021)
Highlights • Neutralizing antibodies could be isolated from convalescent patients or libraries. • Different epitopes such as RBD and NTD were identified by structural studies. • Heavy chain germline genes IGHV3-30, IGHV3-53 and IGHV3-66 are enr
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
It is known that even the adaptive components of the immune system are based on genetic traits common to all individuals, and that diversity is shaped by the lifelong contacts with different non-self antigens, including those found on infectious path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd1ec82106c523f5efc79cc1006da95
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84931575773&doi=10.1016/j.smim.2015.03.008&partnerID=40&md5=30c4d599ad16f0fce5cc22e7e5771ba5
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84931575773&doi=10.1016/j.smim.2015.03.008&partnerID=40&md5=30c4d599ad16f0fce5cc22e7e5771ba5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Williams, S. C., Frippiat, J.-P., Tomlinson, I. M., Ignatovich, O., Lefranc, M. P., Winter, G.
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 1996, 264 (2), pp.220--232. ⟨10.1006/jmbi.1996.0636⟩
Journal of Molecular Biology, Elsevier, 1996, 264 (2), pp.220--232. ⟨10.1006/jmbi.1996.0636⟩
We recently completed a map of the human immunoglobulin lambda (IGL) locus on chromosome 22q11.2 and showed that the V-lambda genes are arranged in three distinct clusters, each containing members of different V-lambda families. We have now sequenced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::168a7be4d753a4ea5bbe8fe851355e39
https://hal.archives-ouvertes.fr/hal-02194147
https://hal.archives-ouvertes.fr/hal-02194147