Zobrazeno 1 - 10
of 1 158
pro vyhledávání: '"antiarrhythmics"'
Autor:
Valentina Doldi, Monica Tortoreto, Maurizio Colecchia, Massimo Maffezzini, Stefano Percio, Francesca Giammello, Federico Brandalise, Paolo Gandellini, Nadia Zaffaroni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Cancer-associated fibroblasts (CAFs) play a significant role in fueling prostate cancer (PCa) progression by interacting with tumor cells. A previous gene expression analysis revealed that CAFs up-regulate genes coding for voltage
Externí odkaz:
https://doaj.org/article/20799a1a00964aa6ac3fbdf54da9a7de
Autor:
G. V. Mokrov
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 3-11 (2023)
β-Blockers are one of the oldest classes of cardioprotectors used in the treatment of cardiovascular diseases. They reduce the heart rate, have a hypotensive effect, inhibit myocardial contractility and have antiarrhythmic properties. In the series
Externí odkaz:
https://doaj.org/article/f24338749443437585384311e4a8bb24
Autor:
Alexandra T. Geanacopoulos, Benjamin Zielonka, Miriam T. Fox, Sarah Kerr, Kristina D. Chambers, Robert Przybylski, Michele M. Burns
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 1, Pp n/a-n/a (2024)
Abstract Antiarrhythmic medications are fundamental in the acute and chronic management of pediatric arrhythmias. Particularly in the pediatric patient population, associated antiarrhythmic toxicities represent important potential adverse effects. Em
Externí odkaz:
https://doaj.org/article/89574c91788b4dcd8295c9e314ce97d1
Autor:
G. V. Mokrov
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 3-19 (2023)
The hERG subtype potassium channel (Kv11.1) is one of the most important and one of the most studied biological targets for the creation of cardioprotective agents. A large number of both blockers and activators/modulators of the hERG channel have be
Externí odkaz:
https://doaj.org/article/43a1aac1c6584e51b74bcc85df18821e
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAntiarrhythmic drugs (AADs) are frequently prescribed following catheter ablation (CA) for atrial fibrillation (AF). However, to date, there is a lack of large-scale, multicenter controlled studies that have confirmed the efficacy of AADs i
Externí odkaz:
https://doaj.org/article/95293451ec834258a51a3b5f3d6c6fcd
Akademický článek
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Akademický článek
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Autor:
G. V. Mokrov
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 3-10 (2022)
Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels, primarily their HCN4 subtype, are one of the promising targets for the development of cardioprotective agents. HCN channel blockers have a selective bradycardic effect, preserving
Externí odkaz:
https://doaj.org/article/4692d7599df54021acc898ec8c7f39fe
Autor:
G. V. Mokrov
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 3-17 (2022)
Cardiovascular diseases (CVD) are widespread and the leading cause of morbidity and mortality worldwide. Drugs for the treatment of CVD have been developed since the beginning of the 20th century. To date, a large number of cardioprotective agents of
Externí odkaz:
https://doaj.org/article/1f57fcaccda64e69a19d90c11708e3ef
Autor:
Muhammad Naveed, Aiman Saleh A. Mohammed, Leila Topal, Zsigmond Máté Kovács, Csaba Dienes, József Ovári, Norbert Szentandrássy, János Magyar, Tamás Bányász, János Prorok, Norbert Jost, László Virág, István Baczkó, András Varró, Péter P. Nánási, Balázs Horváth
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2383 (2023)
The present study was designed to test the hypothesis that the selectivity of blocking the late Na+ current (INaL) over the peak Na+ current (INaP) is related to the fast offset kinetics of the Na+ channel inhibitor. Therefore, the effects of 1 µM G
Externí odkaz:
https://doaj.org/article/4d6e1b0b3ba44596a4eb96b73ed834ff