Zobrazeno 1 - 10
of 2 719
pro vyhledávání: '"anti-tumour"'
Autor:
Rajdeep Chakraborty, Thiri Zaw, Pallavi Khodlan, Charbel Darido, Giuseppe Palmisano, Arthur Chien, Aidan Tay, Shoba Ranganathan, Fei Liu
Publikováno v:
Cancer Reports, Vol 7, Iss 9, Pp n/a-n/a (2024)
ABSTRACT Introduction Salivary gland adenoid cystic carcinoma (ACC), mucoepidermoid carcinoma (MEC) and oral squamous cell carcinoma (OSCC) occurs within the head and neck region. So far immune check point inhibitors failed in ACC. Gipie (CCDC88B) is
Externí odkaz:
https://doaj.org/article/37799b2a5d364667904402320807c6ec
Autor:
Andrea Scafidi, Frida Lind-Holm Mogensen, Eleonora Campus, Alexandros Pailas, Katrin Neumann, Nathalie Legrave, François Bernardin, Sandro L. Pereira, Paul M.A. Antony, Nathalie Nicot, Michel Mittelbronn, Anne Grünewald, Petr V. Nazarov, Aurélie Poli, Eric Van Dyck, Alessandro Michelucci
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37792- (2024)
Background: Epidemiological studies suggest that metformin reduces the risk of developing several types of cancer, including gliomas, and improves the overall survival in cancer patients. Nevertheless, while the effect of metformin on cancer cells ha
Externí odkaz:
https://doaj.org/article/b221e5f5aea84d3ab983d6c758a224c5
Publikováno v:
Reumatismo (2024)
This case series aims to characterize the development of systemic lupus erythematosus (SLE) induced by anti-tumor necrosis factor α (anti-TNFα) therapy in patients with inflammatory rheumatic diseases, namely rheumatoid arthritis (RA), spondylarthr
Externí odkaz:
https://doaj.org/article/267684fb9ff74a6cb1d163f5ce8bbdb0
Autor:
Jialu Cui, Lin Lin, Feiran Hao, Zhuo Shi, Yehui Gao, Tingyu Yang, Chunqi Yang, Xiangjun Wu, Rong Gao, Yi Ru, Fangyang Li, Chengrong Xiao, Yue Gao, Yuguang Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Epimedium Folium has been extensively utilized for medicinal purposes in China for a significant period. This review undertakes a comprehensive examination of literature pertaining to Epimedium and its metabolites over the past decade, drawing from d
Externí odkaz:
https://doaj.org/article/70c7e423467a49e9be9904f4af007497
Autor:
Arteen Arzivian, Brett Jones, Fredrick Joshua, Miriam Paul, Thomas Lynch, Martin Brown, Robin Gasiorowski
Publikováno v:
Case Reports in Gastroenterology, Vol 18, Iss 1, Pp 221-230 (2024)
Introduction: Whipple’s disease is a rare condition that can present with atypical and non-specific features requiring a high index of suspicion for diagnosis. Case Presentation: We present a case of a man in his 40s with peripheral arthritis and b
Externí odkaz:
https://doaj.org/article/1fed07e14ca84d71893f28f11a6ddcba
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background The modification of N6‐methyladenosine (m6A) plays a pivotal role in tumor by altering both innate and adaptive immune systems through various pathways, including the regulation of messenger RNA. The YTH domain protein family, a
Externí odkaz:
https://doaj.org/article/95c982a41d3348a89e57f4f066279a9e
Autor:
Zizhuo Li, Anqi Lin, Zhifei Gao, Aimin Jiang, Minying Xiong, Jiapeng Song, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Background and main body The anti‐tumour and tumour‐promoting roles of B cells in the tumour microenvironment (TME) have gained considerable attention in recent years. As essential orchestrators of humoral immunity, B cells potentially p
Externí odkaz:
https://doaj.org/article/7932b3d021244cff9e56e21bc52d6714
Autor:
Aleksandrs Pustenko, Anastasija Balašova, Alessio Nocentini, Claudiu T. Supuran, Raivis Žalubovskis
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 216-224 (2023)
The synthesis of 3H-1,2-benzoxaphosphepine 2-oxides and evaluation of their inhibitory activity against human carbonic anhydrase (hCA) isoforms I, II, IX, and XII are described. The target compounds were obtained via a concise synthesis from commerci
Externí odkaz:
https://doaj.org/article/f21ae4aebe2a4ab681319cf3e3aae23d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10120 (2024)
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment by enhancing anti-tumour immune responses, demonstrating significant efficacy in various malignancies, including melanoma. However, over 50% of patients experience limited or no re
Externí odkaz:
https://doaj.org/article/9758c773a8b94adb93898f0105338499
Autor:
Sumeyye Cesur
Publikováno v:
Ceramics-Silikáty, Vol 67, Iss 4, Pp 411-419 (2023)
Plants have been used for medicinal purposes for thousands of years. Knowledge of traditional medicine has encouraged the further exploration of medicinal plants as potential drugs. Therefore, in this study, IVE-loaded PLA/PEG nanofibrous mats were s
Externí odkaz:
https://doaj.org/article/cb277858dc804e24affe417a5cae1064