Zobrazeno 1 - 10
of 2 208
pro vyhledávání: '"anti-tumor immunity"'
Autor:
Liam F. Spurr, Sean P. Pitroda
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Recent studies have linked elevated tumor aneuploidy to anti-tumor immune suppression and adverse survival following immunotherapy. Herein, we provide supportive evidence for tumor aneuploidy as a biomarker of response to immunotherapy in pa
Externí odkaz:
https://doaj.org/article/27afba756f854d3d8ae09d61094408de
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background In triple-negative breast cancer (TNBC) therapy, insufficient tumor infiltration by lymphocytes significantly hinders the efficacy of immune checkpoint inhibitors. We have previously demonstrated that Hainanenin-1 (HN-1), a host d
Externí odkaz:
https://doaj.org/article/4e8922e57b7c443bbe67f7c718280b7a
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Chemotherapy and immunotherapy have shown no significant outcome for unresectable pancreatic ductal adenocarcinoma (PDAC). Multi-drug combination therapy has become a consensus in clinical trials to explore how to arouse anti-tumor immunity
Externí odkaz:
https://doaj.org/article/636570c8b9454344bfa1c84aa7444ff6
Autor:
Run Xing Luo, Huai Liang Li, Yu Xiang Jia, Meng Gao, Zhao Yang Gao, Yi Ji, Shan Deng, Jie Ge Huo, Jian Zhang, Dong Jian Zhang
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39071- (2024)
The traditional Chinese medicine (TCM) formulation Shengqiyichang Decoction (SQYCD) has been reported to stimulate host immunity, and it has been administered for the treatment of colorectal cancer (CRC). Here, we applied network and bioinformatics a
Externí odkaz:
https://doaj.org/article/f6434f7c2a304f519ca76f128b5b32fa
Autor:
Yuetong Wang, Qiaoming Li, Yahui Ding, Chenfei Luo, Jun Yang, Na Wang, Ning Jiang, Tiange Yao, Guohao Wang, Guoming Shi, Steven X. Hou
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract The small G protein Arf1 has been identified as playing a selective role in supporting cancer stem cells (CSCs), making it an attractive target for cancer therapy. However, the current Arf1 inhibitors have limited translational potential due
Externí odkaz:
https://doaj.org/article/3123fbd059c74f3b8874b217b59b7168
Autor:
Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells such as T cells, B cells, and Dendritic Cells (DCs), as well as fibroblasts, formed postnatally in response to signals from cytokines and chemokines. Central to the function
Externí odkaz:
https://doaj.org/article/02a9a8a5f7224814a31a9a5c36c57470
Autor:
Hui Zeng, Hu Li, Li Wang, Shuang You, Shuaibin Liu, Xiaojing Dong, Fan He, Jingcong Dai, Quan Wei, Zhiyong Dong, Yanli Zhang, Jingbo Yang, Xia Yang, Jian Wang, Lina Hu
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101220- (2024)
Ovarian cancer (OC) is one of the leading causes of death from malignancy in women and lacks safe and efficient treatment. The novel biomaterial, recombinant humanized collagen type III (rhCOLIII), has been reported to have various biological functio
Externí odkaz:
https://doaj.org/article/a08b494f92fc4ac6a8b1d4bb2361f71a
Autor:
Linwen Lv, Junzhe Zhang, Yujiao Wang, Haojun Liang, Qiuyang Liu, Fan Hu, Hao Li, Wenxi Su, Junhui Zhang, Ranran Chen, Ziteng Chen, Zhijie Wang, Jiacheng Li, Ruyu Yan, Mingxin Yang, Ya‐nan Chang, Juan Li, Tianjiao Liang, Gengmei Xing, Kui Chen
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Radiated tumor cell‐derived extracellular vesicles (RT‐EVs) encapsulate abundant DNA fragments from irradiated tumor cells, in addition to acting as integrators of multiple tumor antigens. Accumulating evidence indicates these DNA fragme
Externí odkaz:
https://doaj.org/article/f9357274b19e45459d5bb9e71baecaaa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The human microbiome has recently emerged as a focal point in cancer research, specifically in anti-tumor immunity, immunotherapy, and chemotherapy. This review explores microbial-derived metabolites, emphasizing their crucial roles in shaping fundam
Externí odkaz:
https://doaj.org/article/800efd59fd10408e9c4c99aaa94c085b