Zobrazeno 1 - 10
of 1 353
pro vyhledávání: '"anti-pd1"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Objective Endometrial cancer is stepping into the era of precision therapy. Genomic test is recommended for newly diagnostic patients. However, outpatients displayed more complex characteristics. Here, we elucidated the clinical characterist
Externí odkaz:
https://doaj.org/article/6f5f27f221304056aa0a5b4bf7612f04
Autor:
Bin Wang, Yue Pan, Yongjie Xie, Cong Wang, Yinli Yang, Haiyan Sun, Zhuchen Yan, Yameng Cui, Ling Li, Yaoyao Zhou, Weishuai Liu, Zhanyu Pan
Publikováno v:
Biological Procedures Online, Vol 26, Iss 1, Pp 1-21 (2024)
Abstract Pancreatic cancer is a devastating malignancy with a high mortality rate, poor prognosis, and limited treatment options. The tumor microenvironment (TME) plays a crucial role in tumor progression and therapy resistance. Multiple subpopulatio
Externí odkaz:
https://doaj.org/article/3878701f784f498fbf03f76b30e3dd89
Autor:
Andrea York Tiang Teo, Chun En Yau, Chen Ee Low, Jarett Vanz-Brian Pereira, Julia Yu Xin Ng, Tse Kiat Soong, Jack Yu Tung Lo, Valerie Shiwen Yang
Publikováno v:
EClinicalMedicine, Vol 77, Iss , Pp 102870- (2024)
Summary: Background: Mucosal melanomas (MM) are an aggressive subtype of melanoma. Given the rarity of this disease, the conduct of clinical trials is challenging and has been limited. Current treatment options have been extrapolated from the more co
Externí odkaz:
https://doaj.org/article/b9bb923f8cc0410aa7ef716a519f6b4f
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundAnti-PD1 antibodies have gained popularity in the treatment of skin cancers. These drugs have been FDA approved for treatment of cutaneous melanoma and unresectable/metastatic squamous cell carcinoma of the skin. However, the use of anti-PD
Externí odkaz:
https://doaj.org/article/528f1b031da34f1fa9ef836afd616e0f
Autor:
Chie Kudo-Saito, Hiroshi Imazeki, Hiroki Ozawa, Hirofumi Kawakubo, Hidekazu Hirano, Narikazu Boku, Ken Kato, Hirokazu Shoji
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102075- (2024)
Peritoneal tumor dissemination and subsequent malignant tumor ascites (MTA) occur unexpectedly and repeatedly in patients with gastrointestinal (GI) cancers, and worsen quality of life and prognosis of the patients. Various treatments have been clini
Externí odkaz:
https://doaj.org/article/9a1d813fda324317aa1ac7ae97784b95
Autor:
Philippe D. Gascard, Xianhong Wang, Mehdi Nosrati, Kevin B. Kim, Mohammed Kashani-Sabet, Thea D. Tlsty, Stanley P. Leong, Mary J. C. Hendrix
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Advanced melanoma is considered the most aggressive and deadly form of skin cancer whose incidence has been rising over the past three decades. In the absence of treatment, the median overall survival for advanced-stage metastatic disease is less tha
Externí odkaz:
https://doaj.org/article/b4ac4159bea44b82a706e5f6f3c885c8
Autor:
Camélia Benhayoun, Anne Bénédicte Duval Modeste, MD, Clémence Tamarit, MD, Pascal Joly, PhD, Raphaël Janela-Lapert, MD
Publikováno v:
JAAD Case Reports, Vol 50, Iss , Pp 44-46 (2024)
Externí odkaz:
https://doaj.org/article/0e402b70ee8f4feaaf339020c746ab82
Autor:
Guoqiang Sun, Chuan Liu, Zhengqing Lu, Jinyu Zhang, Hengsong Cao, Tian Huang, Mingrui Dai, Hanyuan Liu, Tingting Feng, Weiwei Tang, Yongxiang Xia
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Immunotherapy combined with molecular targeted therapy is increasingly popular in patients with advanced hepatocellular carcinoma (HCC). However, immune-related adverse events(irAEs) brought on by immunotherapy increase the likeli
Externí odkaz:
https://doaj.org/article/24ce806c9e674db6a4bcbc4c4860306f
Autor:
María del Mar Noblejas-López, Elena García-Gil, Pedro Pérez-Segura, Atanasio Pandiella, Balázs Győrffy, Alberto Ocaña
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Regulatory T cells (Tregs) is a subtype of CD4+ T cells that produce an inhibitory action against effector cells. In the present work we interrogated genomic datasets to explore the transcriptomic profile of breast tumors with high expressio
Externí odkaz:
https://doaj.org/article/74224a059ba148d49dfab9e6ca39f072
Autor:
Li Xu, Jinzhang Chen, Chang Liu, Xiaoling Song, Yanqiao Zhang, Haitao Zhao, Sheng Yan, Weidong Jia, Zheng Wu, Yabing Guo, Jiayin Yang, Wei Gong, Yue Ma, Xiaobo Yang, Zhenzhen Gao, Nu Zhang, Xin Zheng, Mengyu Li, Dan Su, Minshan Chen
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Lenvatinib is widely used in treatment of unresectable hepatocellular carcinoma (uHCC), but the benefit of its combination with immunotherapy needs to be verified. This study evaluated the efficacy and safety of tislelizumab plus
Externí odkaz:
https://doaj.org/article/c3ae2efaf43843d5896283b1c2eb7e47