Zobrazeno 1 - 10
of 2 982
pro vyhledávání: '"anti-DNA"'
Autor:
Tatiana S. Novikova, Evgeny A. Ermakov, Elena V. Kostina, Alexander N. Sinyakov, Alexey E. Sizikov, Georgy A. Nevinsky, Valentina N. Buneva
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9887-9903 (2023)
Anti-DNA antibodies are known to be classical serological hallmarks of systemic lupus erythematosus (SLE). In addition to high-affinity antibodies, the autoantibody pool also contains natural catalytic anti-DNA antibodies that recognize and hydrolyze
Externí odkaz:
https://doaj.org/article/83c7de25dc9e4570aaf20eede051c3ac
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2556 (2024)
Antibodies to DNA are a diverse set of antibodies that bind sites on DNA, a polymeric macromolecule that displays various conformations. In a previous study, we showed that sera of normal healthy subjects (NHS) contain IgG antibodies to Z-DNA, a left
Externí odkaz:
https://doaj.org/article/0196837542d44441a74f0769b0b835da
Autor:
Tetsuo Kubota
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16499 (2023)
Anti-DNA antibodies are hallmark autoantibodies produced in systemic lupus erythematosus (SLE), but their pathogenetic role is not fully understood. Accumulating evidence suggests that some anti-DNA antibodies enter different types of live cells and
Externí odkaz:
https://doaj.org/article/8a1a08d7a0fa464391210e63996dd5eb
Publikováno v:
Immunological Medicine, Vol 44, Iss 2, Pp 124-135 (2021)
Antibodies specific for cardiolipin (CL)-β2-glycoprotein I (β2GPI) are known to induce tissue factor (TF) expression by monocytes and endothelial cells which leads to a prothrombotic state in antiphospholipid syndrome (APS), but the mechanism is no
Externí odkaz:
https://doaj.org/article/01df479967374dbda7921f75dac4a14a
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 13, Pp 39-49 (2020)
Elliott Lever,1 Marta R Alves,2 David A Isenberg1 1Centre for Rheumatology, Division of Medicine, University College Hospital London, London, UK; 2Internal Medicine, Department of Medicine, Centro Hospitalar do Porto, Porto, PortugalCorrespondence: D
Externí odkaz:
https://doaj.org/article/4d9a96551ade487199b0530433f9cf49
Autor:
Ole Petter Rekvig
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Systemic lupus erythematosus (SLE) is diagnosed and classified by criteria, or by experience, intuition and traditions, and not by scientifically well-defined etiology(ies) or pathogenicity(ies). One central criterion and diagnostic factor is founded
Externí odkaz:
https://doaj.org/article/3715c5221d3f4a60aaabadf86f357349
Autor:
Han Wang, Antonia Margarethe Stehr, Jeeshan Singh, Leticija Zlatar, Arndt Hartmann, Katja Evert, Elisabeth Naschberger, Saskia von Stillfried, Peter Boor, Luis E. Muñoz, Jasmin Knopf, Michael Stürzl, Martin Herrmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4101 (2023)
During inflammatory responses, neutrophils enter the sites of attack where they execute various defense mechanisms. They (I) phagocytose microorganisms, (II) degranulate to release cytokines, (III) recruit various immune cells by cell-type specific c
Externí odkaz:
https://doaj.org/article/8fba3635a58d40c6aaf459ee06b1d3ae
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with widespread inflammation, immune dysregulation, and is associated with the generation of destructive anti-DNA autoantibodies. We have shown previously the immune modulatory proper
Externí odkaz:
https://doaj.org/article/d6ae1a7560b5498c95a04b8e4056203c