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pro vyhledávání: '"animal testing alternative"'
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Publikováno v:
Folia Pharmacologica Japonica. 156:208-213
The mission of regulatory science is to promote human longevity by providing safer and more effective drugs and ensuring human health. At present, various in vitro and in vivo evaluation methods are used for drug development, and no major problems ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3922ae819f0d5d7d75ba0140f5e66c
https://doi.org/10.1254/fpj.21020
https://doi.org/10.1254/fpj.21020
Publikováno v:
Archives of Toxicology
The COVID-19-inducing virus, SARS-CoV2, is likely to remain a threat to human health unless efficient drugs or vaccines become available. Given the extent of the current pandemic (people in over one hundred countries infected) and its disastrous effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ef779e0623d5390e7a0169554ee44c
https://doi.org/10.1007/s00204-020-02787-2
https://doi.org/10.1007/s00204-020-02787-2
Autor:
Silvia H Pérez Damonte, Alejandro Aguilar, Silvia Wikinski, Mercedes Izaguirre, Mariela Lenze, María Laura Gutiérrez, Martín Nicolás Rivero
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 153
The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used alternative tests for prediction of ocular irritation of cosmetic products. There are different HET-CAM protocols widely accepted, but there is no information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d79030f87bb44f8e1fbd9e29390d325
https://pubmed.ncbi.nlm.nih.gov/33887397
https://pubmed.ncbi.nlm.nih.gov/33887397
Autor:
Petra S. Kern, Kirstin Kosemund-Meynen, Maciej Stępnik, Christophe Rousselle, Natalie von Goetz, Janine Ezendam, Gladys Ouedraogo, Ulrike Bernauer, Emilio Benfenati, Mark T. D. Cronin, Carsten Goebel, Qasim Chaudhry, Paul L. Carmichael, Eric Gaffet, Pieter Jan Coenraads, Heli M. Hollnagel, Laurent Bodin, Berit Granum, Corrado L. Galli, Andrew Worth, Vera Rogiers, Matthew P. Dent, Maria Dusinska, Tamara Vanhaecke, Eirini Panteri, Corie A. Ellison
Publikováno v:
Toxicology
Toxicology, Elsevier, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩
Toxicology, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩
Toxicology, Elsevier, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩
Toxicology, 2020, 436, pp.152421. ⟨10.1016/j.tox.2020.152421⟩
International audience; Although the need for non-animal alternatives has been well recognised for the human health hazard assessment of chemicals in general, it has become especially pressing for cosmetic ingredients due to the full implementation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c96edc17a3c3d4598238bfda31dc339
https://doi.org/10.1016/j.tox.2020.152421
https://doi.org/10.1016/j.tox.2020.152421
Autor:
Stefano Lorenzetti, P. Hubert, Andrea Gissi, Francesco Nevelli, Francesca Caloni, Gabriele Cruciani, Gabriele Aquilina, A. Rainer, I. De Angelis, Augusto Vitale, Laura Goracci, Eliana M. Coccia, Costanza Rovida, Pietro Cozzini, A. Fouassier, T. Heinonen, F. Madia
Publikováno v:
ALTEX. 37(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59434bec13d18023cc35f228b2b7468
https://pubmed.ncbi.nlm.nih.gov/32242640
https://pubmed.ncbi.nlm.nih.gov/32242640
Autor:
Erik J. Tokar, Anthony L. Luz
Publikováno v:
Toxicological Sciences. 165:31-39
Millions of children are born each year with a birth defect. Many of these defects are caused by environmental factors, although the underlying etiology is often unknown. In vivo mammalian models are frequently used to determine if a chemical poses a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c503e118440d6ddf66abd5b54e6b4bbc
https://doi.org/10.1093/toxsci/kfy174
https://doi.org/10.1093/toxsci/kfy174
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
BMC Cancer
BMC Cancer
Background Improving our understanding of cancer and other complex diseases requires integrating diverse data sets and algorithms. Intertwining in vivo and in vitro data and in silico models are paramount to overcome intrinsic difficulties given by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7aa884c6421894cab181fb1b01ed75a
http://link.springer.com/article/10.1186/s12885-018-4302-0
http://link.springer.com/article/10.1186/s12885-018-4302-0
Autor:
Rebecca A. Clewell, Brian D. Cholewa, Miyoung Yoon, Jessica K. Hartman, Melvin E. Andersen, Martin B. Phillips, Kamel Mansouri, Chantel I. Nicolas, Melyssa S. Minto, Katherine M. Dunnick, Patrick D. McMullen, Harvey J. Clewell, Scott Slattery
Publikováno v:
Toxicology in Vitro. 48:310-317
An evolving regulatory, scientific, and legislative landscape is driving a fundamental change in how chemical safety decisions are made. As we move to implement changes, regulatory agencies and industry are beginning to adopt tiered approaches, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4774a208894bb6844f796a9ab0a329
https://doi.org/10.1016/j.tiv.2018.01.027
https://doi.org/10.1016/j.tiv.2018.01.027
Publikováno v:
和洋女子大学紀要 = The journal of Wayo Women's University. 58:175-183
管理栄養士養成課程においては、ラットやマウスなどのモデル動物を用いた実験実習が行われている。動物実験は、栄養学や生化学、および解剖学など教科書で学んだ内容を短期間で体
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::cad84349dac1e38fe90341ee63213742
http://id.nii.ac.jp/1159/00001570/
http://id.nii.ac.jp/1159/00001570/