Zobrazeno 1 - 10
of 1 917
pro vyhledávání: '"animal experiments"'
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 691-701 (2024)
Context Achyranthes bidentata Blume (ABB), a plant of Amaranthaceae family, has been one of the more commonly used phytomedicine remedies for thousands of years, and recent studies have highlighted the efficacy of its extracts in the treatment of ost
Externí odkaz:
https://doaj.org/article/1d110bfbce1844459b7a0535c6439085
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Nicotinamide mononucleotide (NMN), a crucial intermediate in NAD + synthesis, can rapidly transform into NAD + within the body after ingestion. NMN plays a pivotal role in several important biological processes, including energy metabolism,
Externí odkaz:
https://doaj.org/article/dc75ce63963f41f79e0e7a04cc9581a9
Autor:
Thorsten Rudroff
Publikováno v:
Neurology International, Vol 16, Iss 4, Pp 805-820 (2024)
Animal experimentation has long been a cornerstone of neurology research, but it faces growing scientific, ethical, and economic challenges. Advances in artificial intelligence (AI) are providing new opportunities to replace animal testing with more
Externí odkaz:
https://doaj.org/article/36233fba57954483be66190089785dea
Autor:
Dongqiang Luo, Xiaolu Gao, Xianqiong Zhu, Jiayu Wu, Qingyi Yang, Ying Xu, Yuxuan Huang, Xiaolin He, Yan Li, Pengfei Gao
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Steroid-induced osteonecrosis of femoral head (SONFH) is a severe health risk, and this study aims to identify immune-related biomarkers and pathways associated with the disease through bioinformatics analysis and animal experimen
Externí odkaz:
https://doaj.org/article/bd55fec624b6485f86285f94dfc34e8c
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveWe aimed to evaluate the efficacy of stem cell-derived exosomes for treating ischemic stroke and to screen for the optimal administration strategy.MethodsWe searched PubMed, Web of Science, Embase, Cochrane Library, and Scopus databases for
Externí odkaz:
https://doaj.org/article/b86cdb5af7134a2db291799d41717267
Publikováno v:
SLAS Technology, Vol 29, Iss 5, Pp 100184- (2024)
The advanced prostate biopsy robot system has broad application prospects in clinical practice, but due to the deformation and distortion between MR-TRUS (magnetic resonance transrectal ultrasound) images, it poses challenges in biopsy accuracy and s
Externí odkaz:
https://doaj.org/article/c25431f227754cbeab4d6f9b20093952
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 3, Pp 290-296 (2024)
Objective To investigate the effect of polymerized human cord hemoglobin (PolyCHb) in chemoimmunotherapy for breast cancer in mice. Methods A 4T1 breast cancer in situ tumor model was established, and 15 mice were randomly divided into 3 groups: blan
Externí odkaz:
https://doaj.org/article/6fefc4e2398e44789e5016444adc4267
Autor:
Du Yijie, Zhao Siqi, Huang Ruiyin, Shi YuJing, Meng Hong, Dong Yinmao, Yang Tao, Luo Changyong
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveThis research aims to explore how Puerariae Lobatae Radix regulates sebaceous gland secretion using network pharmacology, and validate its effects on important targets through animal studies.MethodsThis study utilized UPLC-EQ-MS to analyze P
Externí odkaz:
https://doaj.org/article/34d1fbb22b204ec7b4dcab9b1c21d93c
Autor:
Min Feng, Qiang Zhou, Huimin Xie, Chang Liu, Mengru Zheng, Shuyu Zhang, Songlin Zhou, Jian Zhao
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 512-518 (2024)
CD36 is a highly glycosylated integral membrane protein that belongs to the scavenger receptor class B family and regulates the pathological progress of metabolic diseases. CD36 was recently found to be widely expressed in various cell types in the n
Externí odkaz:
https://doaj.org/article/7d97fd8a436048fd9e9707261e178223
Autor:
Monique R. E. Janssens
Publikováno v:
Animals, Vol 14, Iss 18, p 2643 (2024)
If we want to take sentient non-human animals and their interests seriously, we can try to ask for their consent before using them for human purposes. With mentally competent humans, we speak of informed consent: for them to participate in scientific
Externí odkaz:
https://doaj.org/article/f042e4d480b14602b4168ecf5b29e83b