Zobrazeno 1 - 10
of 1 521
pro vyhledávání: '"angiotensin-converting enzyme (ACE)"'
Autor:
Amit Chandra Das, James M. Nichols, Caitlin V. Crelli, Lu Liu, Riddhi Vichare, Hoang Vu Pham, Caitlyn M. Gaffney, Fisher R. Cherry, Peter M. Grace, Andrew J. Shepherd, Jelena M. Janjic
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract A major and irreversible complication of diabetes is diabetic peripheral neuropathy (DPN), which can lead to significant disability and decreased quality of life. Prior work demonstrates the peptide hormone Angiotensin II (Ang II) is release
Externí odkaz:
https://doaj.org/article/64ead22a811e40809c09ebfdfe02ebad
Publikováno v:
Journal of Ophthalmology, Iss 1, Pp 54-60 (2024)
Purpose: To evaluate the relationship between angiotensin-converting enzyme (ACE; rs4340) gene variants and the retinal changes as evidenced by fundoscopy in patients with various clinical courses of COVID-19. Material and Methods: Ninety-four COVID
Externí odkaz:
https://doaj.org/article/35e70fc838dc433f845a0d2bfbb10d00
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3962 (2024)
The aim of the present study was to determine the ACE inhibitory activity of aqueous extracts of olive pomace and to understand whether they represent a good source of bioactive LMW peptides for nutritional and pharmacological applications. We produc
Externí odkaz:
https://doaj.org/article/f8e681c629024a599fb0f88586a27188
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/b23a9377ad4447ea834690511fd8c502
Autor:
Amany Belal, Mohamed A. Elanany, Ahmed A. Al-Karmalawy, Ahmed Elkamhawy, Mohammed A. S. Abourehab, Heba I. Ghamry, Ahmed B. M. Mehany
Publikováno v:
Journal of Taibah University for Science, Vol 17, Iss 1 (2023)
New pyrrolidine derivatives with more than 50% structural similarity with captopril were designed to get new captopril mimics with superior potential to act on both peripheral and central ACE. Further optimization was carried out through pharmacophor
Externí odkaz:
https://doaj.org/article/68c4605028e142cd83bd4dc65f796cd8
Autor:
DuoYao Cao, Suguru Saito, LiMin Xu, Wei Fan, Xiaomo Li, Faizan Ahmed, Predrag Jovanovic, Tomohiro Shibata, Mingtian Che, Ellen A. Bernstein, Jorge Gianni, Ajit S. Divakaruni, Derick Okwan-Duodu, Zakir Khan, Celine E. Riera, Fanfan Chen, Kenneth E. Bernstein
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The pathogenesis of atherosclerosis is defined by impaired lipid handling by macrophages which increases intracellular lipid accumulation. This dysregulation of macrophages triggers the accumulation of apoptotic cells and chronic inflammation which c
Externí odkaz:
https://doaj.org/article/7c8a952ad81f4988a3c2646c8a32d185
Autor:
Hamid Tanzadehpanah, Elham Lotfian, Amir Avan, Sahar Saki, Sima Nobari, Roghaye Mahmoodian, Mohsen Sheykhhasan, Mohamad Hosein Shafiee Froutagh, Farzaneh Ghotbani, Raoufeh Jamshidi, Hanie Mahaki
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115321- (2023)
The occurrence of a novel coronavirus known as severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), created a serious challenge worldwide. SARS-CoV-2 has high infectivity, the ability to be transmitted even during the asymptomatic phase, and
Externí odkaz:
https://doaj.org/article/73750e8ef75a4f208bbd7f1d21b845cb
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 360 (2024)
Angiotensin-converting enzyme (ACE) inhibitors are used primarily in the treatment of hypertension, heart failure, and in the acute phase of myocardial infarction. Lisinopril [N2-[(1S)-1-car-boxy-3-phenylpropyl]-L-lysyl-L-proline], enalapril [(S)-1-[
Externí odkaz:
https://doaj.org/article/ecf4ba430a8c4f9a8a3ea4622211b083
Publikováno v:
International Journal of Applied Biology, Vol 6, Iss 2, Pp 172-178 (2022)
This study aims to determine the bioactivity of the compound quercetin in the peel of Allium cepa L as a natural antihypertensive compound. The chemical structure of the quercetin compound found in Allium cepa L peel was taken from the literature. Th
Externí odkaz:
https://doaj.org/article/573d6034c82d4537995d375569068424
Publikováno v:
Food Science and Human Wellness, Vol 11, Iss 6, Pp 1539-1543 (2022)
In this paper, the antihypertension effect of rice peptide (RP) was studied. With spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) as the research objects, RP disposable gastric and long-term gastric irrigation experiments were carried ou
Externí odkaz:
https://doaj.org/article/e17f001327be40d283086c7356e93988