Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice

Autor: Suzanne Lam, Anne-Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, The Brainbank Neuro-CEB Neuropathology Network, Jean-Luc Picq, Luc Buée, Charles Duyckaerts, Stéphane Haïk, Marc Dhenain

Publikováno v: Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-19 (2022)

Abstract Alzheimer's disease (AD) is characterized by intracerebral accumulations of extracellular amyloid-β (Aβ) plaques and intracellular tau pathology that spread in the brain. Three types of tau lesions occur in the form of neuropil threads, ne

Externí odkaz: https://doaj.org/article/7703dd8fe7624c2187d3305fec73d344

Induction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued from human brains

Autor: Anne-Sophie Hérard, Fanny Petit, Charlotte Gary, Martine Guillermier, Susana Boluda, Clément M. Garin, The Brainbank Neuro-CEB Neuropathology Network, Suzanne Lam, Marc Dhenain

Publikováno v: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)

Abstract In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as after cerebral surgeries. Exper

Externí odkaz: https://doaj.org/article/e5c5d8960af64e8e93784c6732f96349

Pathological changes induced by Alzheimer's brain inoculation in amyloid-beta plaque-bearing mice.

Autor: Lam, Suzanne, Hérard, Anne-Sophie, Boluda, Susana, Petit, Fanny, Eddarkaoui, Sabiha, Cambon, Karine, The Brainbank Neuro-CEB Neuropathology Network, Letournel, Franck, Martin-Négrier, Marie-Laure, Faisant, Maxime, Godfraind, Catherine, Boutonnat, Jean, Maurage, Claude-Alain, Deramecourt, Vincent, Duchesne, Mathilde, Meyronet, David, Fenouil, Tanguy, de Paula, André Mauès, Rigau, Valérie, Vandenbos-Burel, Fanny

Publikováno v: Acta Neuropathologica Communications; 8/16/2022, Vol. 10 Issue 1, p1-19, 19p

Human subiculo-fornico-mamillary system in Alzheimer's disease: Tau seeding by the pillar of the fornix.

Autor: Thierry, Manon, Boluda, Susana, Delatour, Benoît, Marty, Serge, Seilhean, Danielle, Brainbank Neuro-CEB Neuropathology Network, Letournel, Franck, Martin-Négrier, Marie-Laure, Chapon, Françoise, Godfraind, Catherine, Maurage, Claude-Alain, Deramecourt, Vincent, Meyronnet, David, Streichenberger, Nathalie, de Paula, André Maues, Rigau, Valérie, Vandenbos-Burel, Fanny, Duyckaerts, Charles, Plu, Isabelle, Milin, Serge

Publikováno v: Acta Neuropathologica; Mar2020, Vol. 139 Issue 3, p443-461, 19p

SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration.

Autor: Barbier M; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Camuzat A; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Hachimi KE; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Guegan J; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Rinaldi D; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France.; Center for Rare or Early-Onset Dementias, IM2A, Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Paris, France., Lattante S; Sezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Facoltà di Medicina e Chirurgia, Università Cattolica Sacro Cuore; U.O.C. Genetica Medica, Dipartimento di Scienze di Laboratorio e Infettivologico, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Rome, Italy., Houot M; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France.; Center for Rare or Early-Onset Dementias, IM2A, Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Paris, France.; Centre of Excellence of Neurodegenerative Disease (CoEN), Hôpital Pitié-Salpêtrière, Paris, France., Sánchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalunya, Spain., Sabatelli M; Adult NEMO Clinical Center, Unit of Neurology, Department of Aging, Neurological, Orthopedic and Head-Neck Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Section of Neurology, Department of Neuroscience, Faculty of Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy., Antonell A; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalunya, Spain., Molina-Porcel L; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalunya, Spain.; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Catalunya, Spain., Clot F; Unité Fonctionnelle de Neurogénétique Moléculaire et Cellulaire, Département de Génétique et Cytogénétique, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, France., Couratier P; Centre Démences rares University Hospital Limoges, Limoges, France., van der Ende E; Department of Neurology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., van der Zee J; Neurodegenerative Brain Diseases Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Manzoni C; School of Pharmacy, University College London, London, UK., Camu W; Reference Centre for ALS, University Hospital Gui de Chauliac, University of Montpellier, Montpellier, France., Cazeneuve C; Unité Fonctionnelle de Neurogénétique Moléculaire et Cellulaire, Département de Génétique et Cytogénétique, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, France., Sellal F; Neurology Department, Hôpitaux Civils de Colmar, France.; INSERM U-1118, Strasbourg University, Strasbourg, France., Didic M; APHM, Timone, Service de Neurologie et Neuropsychologie, Hôpital Timone Adultes, Marseille, France.; Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France., Golfier V; Service de Neurologie, Centre Hospitalier Yves Le Foll, Saint Brieuc, France., Pasquier F; University of Lille, Inserm UMRS1172, CHU, DISTAlz, LiCEND, F-59000 Lille, France., Duyckaerts C; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France.; Laboratoire de Neuropathologie Escourolle, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France., Rossi G; Division of Neurology V and Neuropathology; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Bruni AC; Regional Neurogenetic Centre, Department of Primary Care, ASP-CZ, Catanzaro, Italy., Alvarez V; Laboratorio de Genética- Hospital Universitario Central de Asturias, Oviedo, Spain.; Instituto de INvestigación Biosanitaria del Principado de Asturias (ISPA), Oviedo, Spain., Gómez-Tortosa E; Department of Neurology, Fundación Jiménez Díaz, Madrid, Spain., de Mendonça A; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Graff C; Department of Geriatric Medicine, Karolinska University Hospital-Huddinge, Stockholm, Sweden., Masellis M; Hurvitz Brain Sciences Program, Sunnybrook Research Institute; Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada., Nacmias B; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Oumoussa BM; Sorbonne Université, Inserm, UMS Production et Analyse des données en Sciences de la vie et en Santé, PASS, Plateforme Post-génomique de la Pitié-Salpêtrière, P3S, F-75013, Paris, France., Jornea L; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Forlani S; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Van Deerlin V; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Gelpi E; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Catalunya, Spain.; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria., Rademakers R; Neurodegenerative Brain Diseases Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Van Swieten J; Department of Neurology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., Le Guern E; Unité Fonctionnelle de Neurogénétique Moléculaire et Cellulaire, Département de Génétique et Cytogénétique, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, France., Van Broeckhoven C; Neurodegenerative Brain Diseases Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Ferrari R; University College London, Institute of Neurology, London, UK., Génin E; Génétique, Génomique Fonctionnelle et Biotechnologies, Faculté de Médecine, Univ Brest, Inserm UMR1078, Brest, France., Brice A; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France., Le Ber I; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Hôpital de la Salpêtrière, Inserm U 1127, CNRS UMR 7225, 75013, Paris, France.; Center for Rare or Early-Onset Dementias, IM2A, Département de Neurologie, AP-HP-Hôpital Pitié-Salpêtrière, Paris, France.

Publikováno v: Brain : a journal of neurology [Brain] 2021 Oct 22; Vol. 144 (9), pp. 2798-2811.