Zobrazeno 1 - 10
of 3 127
pro vyhledávání: '"and the Alzheimer’s Disease Neuroimaging Initiative"'
Autor:
Shan Cong, Xiaohui Yao, Linhui Xie, Jingwen Yan, Li Shen, and the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Background: Human brain structural connectivity is an important imaging quantitative trait for brain development and aging. Mapping the network connectivity to the phenotypic variation provides fundamental insights in understanding the relationship b
Externí odkaz:
https://doaj.org/article/e0a9e07eccc943519502026481e100e0
Autor:
Jolien Schaeverbeke, Emma S Luckett, Silvy Gabel, Mariska Reinartz, Steffi De Meyer, Isabelle Cleynen, Kristel Sleegers, Christine Van Broeckhoven, Guy Bormans, Kim Serdons, Koen Van Laere, Patrick Dupont, Rik Vandenberghe, and the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction The bridging integrator 1(BIN1) rs744373 risk polymorphism has been linked to increased [18F]AV1451 signal in non‐demented older adults (ie., mild cognitive impairment [MCI] plus cognitively normal [CN] individuals). However,
Externí odkaz:
https://doaj.org/article/43f537777e1b4223bd9b6682f5b28538
Autor:
Zhanxiong Wu, Yunyuan Gao, Thomas Potter, Julia Benoit, Jian Shen, Paul E. Schulz, Yingchun Zhang, and The Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Normative aging and Alzheimer’s disease (AD) propagation alter anatomical connections among brain parcels. However, the interaction between the trajectories of age- and AD-linked alterations in the topology of the structural brain network is not we
Externí odkaz:
https://doaj.org/article/7fa36cb3d47d4c29a0a1aeb58f222477
Autor:
Young‐gun Lee, Seun Jeon, Sung Woo Kang, Mincheol Park, Kyoungwon Baik, Han Soo Yoo, Seok Jong Chung, Seong Ho Jeong, Jin Ho Jung, Phil Hyu Lee, Young Ho Sohn, Alan C. Evans, Byoung Seok Ye, and the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Lewy body–related pathology is commonly observed at autopsy in individuals with dementia, but in vivo biomarkers for α‐synucleinopathy are lacking. Methods Baseline cerebrospinal fluid (CSF) biomarkers, polygenic risk score
Externí odkaz:
https://doaj.org/article/d787d3a0b7364cdb963cf1fd8bff7c98
Autor:
Yue Wu, Xingqi Wu, Qiang Wei, Kai Wang, Yanghua Tian, and the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Background: Alzheimer’s disease (AD) is characterized by global deterioration in multiple cognitive domains. In addition to cognitive impairment, depressive symptoms are common issues that trouble AD patients. The neuroanatomical basis of depressiv
Externí odkaz:
https://doaj.org/article/f581e7d0422c419aa498d85ce1b6022f
Autor:
Colin Birkenbihl, Yasamin Salimi, Daniel Domingo‐Fernándéz, Simon Lovestone, AddNeuroMed consortium, Holger Fröhlich, Martin Hofmann‐Apitius, the Japanese Alzheimer's Disease Neuroimaging Initiative, and the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Numerous studies have collected Alzheimer's disease (AD) cohort data sets. To achieve reproducible, robust results in data‐driven approaches, an evaluation of the present data landscape is vital. Methods Previous efforts relie
Externí odkaz:
https://doaj.org/article/6f6fa86906284c78aaa334f0c6932e17
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Tong Tong, Congcong Zhu, John J. Farrell, Zainab Khurshid, Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative, Eden R. Martin, Margaret A. Pericak-Vance, Li-San Wang, William S. Bush, Gerard D. Schellenberg, Jonathan L. Haines, Wei Qiao Qiu, Kathryn L. Lunetta, Lindsay A. Farrer, Xiaoling Zhang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Blood-derived mitochondrial DNA copy number (mtDNA-CN) is a proxy measurement of mitochondrial function in the peripheral and central systems. Abnormal mtDNA-CN not only indicates impaired mtDNA replication and transcription machi
Externí odkaz:
https://doaj.org/article/6359a6836b184b369a74d2bbfb50ce84
Autor:
Sylvain Lehmann, Susanna Schraen-Maschke, Luc Buée, Jean-Sébastien Vidal, Constance Delaby, Christophe Hirtz, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Olivier Hanon, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Current AT(N) stratification for Alzheimer’s disease (AD) accounts for complex combinations of amyloid (A), tau proteinopathy (T) and neurodegeneration (N) signatures. Understanding the transition between these different stages
Externí odkaz:
https://doaj.org/article/c860af25033746cb82e1ae7cdbcb2d80
Autor:
Xiao-jun Jing, Zhi-yuan Zan, Xin Zhou, Yong-lan Xiong, Shu-jiang Ren, Hua Zhang, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 28, Iss 3, Pp 273-283 (2024)
Background Advances in blood biomarker discovery have enabled the improved diagnosis and prognosis of Alzheimer's disease (AD). Most branched-chain amino acids, except isoleucine (Ile), are correlated with both mild cognitive impairment (MCI) and AD.
Externí odkaz:
https://doaj.org/article/c4411d928933473db874d44edf282465