Zobrazeno 1 - 10
of 40 670
pro vyhledávání: '"and il-2"'
Autor:
Faustina Adu, Ebenezer Aniakwaa-Bonsu, Samuel Badu Nyarko, Aikins Sarpong Obeng, Richmond Owusu Ateko, Akwasi Anyanful, Nicholas Ekow Thomford
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Hepatitis B virus (HBV) infection is a public health concern in resource limited settings like Ghana. Over the past decades, it is noted that the natural course of HBV in persons infected are taking a worse turn leading to liver c
Externí odkaz:
https://doaj.org/article/aac4b8181da14e938ec159826c689868
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Low-dose IL-2 (Ld-IL2) has shown favorable therapeutic effects in systemic lupus erythematosus (SLE) therapy. However, previous clinical trials reported an SLE Responder Index-4 (SRI-4) response rate of 65.52%-68%, with approximat
Externí odkaz:
https://doaj.org/article/90bef5d50c0e4e72b7019607f833b32a
Autor:
Shaoju Qian, Ruixue Li, Yeqing He, Hexi Wang, Danqiong Zhang, Aiping Sun, Lili Yu, Xiangfeng Song, Tiesuo Zhao, Zhiguo Chen, Zishan Yang
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Herpes simplex virus type 1 (HSV-1) is a major cause of viral encephalitis, genital mucosal infections, and neonatal infections. Lactococcus lactis (L. lactis) has been proven to be an effective vehicle for delivering protein anti
Externí odkaz:
https://doaj.org/article/f2e1ef0a4c7b476bac2d6b0e7381ac19
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafiq, Thomas S. Riad, Yun Hu, Ailing Huang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background Combining interleukin-2 (IL-2) with radiotherapy (RT) and immune checkpoint blockade (ICB) has emerged as a promising approach to address ICB resistance. However, conventional IL-2 cytokine therapy faces constraints owing to its b
Externí odkaz:
https://doaj.org/article/d5dfdad3aeaf4ef7a03ae6638ec04617
Autor:
Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen
Publikováno v:
Italian Journal of Medicine, Vol 18, Iss 3 (2024)
Tuberculosis (TB) is a serious global public health problem. Detecting the changes of adenosine deaminase (ADA), interleukin (IL)-1β, IL-2, tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ) released from macrophages and monocytes is greatly
Externí odkaz:
https://doaj.org/article/c83d16d8c74e41f7b86e3b69a05ae71b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Discovered over 4 decades ago in the supernatants of activated T cells, interleukin-2 (IL-2) is a potent pleiotropic cytokine involved in the regulation of immune responses. It is required for effector T cell expansion and differentiation as well as
Externí odkaz:
https://doaj.org/article/5d4cfa6eb67d40a39707720e5b598a52
Autor:
Yipin Lv, Wenqing Tian, Yongsheng Teng, Pan Wang, Yongliang Zhao, Zhengyan Li, Shanhong Tang, Weisan Chen, Rui Xie, Muhan Lü, Yuan Zhuang
Publikováno v:
Journal of Advanced Research, Vol 57, Iss , Pp 149-162 (2024)
Introduction: In solid tumors, regulatory T cell (Treg) and mast cell perform different roles depending on the microenvironment. Nevertheless, mast cell and Treg-mediated interactions in gastric cancer (GC) are unclear, as are their regulation, funct
Externí odkaz:
https://doaj.org/article/f7b30dd877f741c3b19726d7d094b5d9
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 44, Iss 1 (2024)
Background Interleukin (IL)-2 is a key cytokine capable of modulating the immune response by activating natural killer (NK) cells. This study was recruited to explore the therapeutic potential of IL-2-activated NK-92 cells in endometriosis in vitro.M
Externí odkaz:
https://doaj.org/article/e76f7f859e7e4f288096a94787673ab1
Autor:
Jiqi Shan, Wei Jing, Yu Ping, Chunyi Shen, Dong Han, Fengsen Liu, Yaqing Liu, Congcong Li, Yi Zhang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTAnti-PD-1 antibody therapy has achieved success in tumor treatment; however, the duration of its clinical benefits are typically short. The functional state of intratumoral CD8+ T cells substantially affects the efficacy of anti-PD-1 antibody
Externí odkaz:
https://doaj.org/article/40929eb3d9084be095904ba4d74e9276
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