Zobrazeno 1 - 10
of 4 021
pro vyhledávání: '"and activator of transcription 3"'
Autor:
Jeonghyeon Moon, Keun-Hyung Cho, JooYeon Jhun, JeongWon Choi, Hyun-Sik Na, Jeong Su Lee, Seung Yoon Lee, Jun-Ki Min, Anan Shetty, Sung-Hwan Park, Seok Jung Kim, Mi-La Cho
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Objective Osteoarthritis (OA) is a degenerative joint disease caused by the breakdown of joint cartilage and adjacent bone. Joint injury, being overweight, differences in leg length, high levels of joint stress, abnormal joint or limb develo
Externí odkaz:
https://doaj.org/article/918bd055aef54a63a6b69ed875df85ba
Publikováno v:
Shipin Kexue, Vol 45, Iss 18, Pp 242-249 (2024)
Signal transducer and activator of transcription 3 (STAT3) exists in the cytoplasm, nucleus, mitochondria, and mitochondria associated endoplasmic reticulum membranes, which is a signal transduction protein involved in various physiological processes
Externí odkaz:
https://doaj.org/article/66f49ffa9911468dbba5f57e28c9e071
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Zinc finger protein 263 (ZNF263) is frequently upregulated in various tumor types; however, its function and regulatory mechanism in colorectal cancer (CRC) have not yet been elucidated. In this study, the expression of ZNF263 was systematic
Externí odkaz:
https://doaj.org/article/5132638c12d14047bd40a37c24b5c3b7
Autor:
Hao Yuan, Ming Zhong, Jie Liu, Shuya Tang, Hongbo Zhu, Qingping Wei, Bingbing Pu, Yongping Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a protein that regulates apoptosis and programmed cell death. This research aims to evaluate its potential role in inhibiting breast cancer cell proliferation, migration, and glycolysis and
Externí odkaz:
https://doaj.org/article/552b122dcb354042b019bf6b3c423bf8
Autor:
Yi Li, Yuyan Dong
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cervical cancer (CC) is a significant global health concern, demanding the consideration of novel therapeutic strategies. The signal transducer and activator of transcription 3 (STAT3) pathway has been implicated in cancer progres
Externí odkaz:
https://doaj.org/article/da7566f9141f43cd8c39fbf94d22cef8
Autor:
Peiyue Luo, Tao Chen, Liying Zheng, Junrong Zou, Jun Zou, Wei Li, Qi Chen, Le Cheng, Biao Qian
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThe calcium-sensitive receptor (CaSR) has been identified as a key factor in the formation of kidney stones. A substantial body of research has illuminated the function of CaSR in stone formation with respect to oxidative stress, epithelial
Externí odkaz:
https://doaj.org/article/e5db2c2925e24db2aac95589445772c3
Autor:
Ao Xu, Ziqing Li, Yangyang Ding, Xiaoyu Wang, Yufang Yang, Lixia Du, Deheng Wang, Shi Shu, Zhifei Wang
Publikováno v:
Brain Research Bulletin, Vol 219, Iss , Pp 111128- (2024)
ABSTRACT: Aims: Electroacupuncture (EA) at Shuigou (GV26) and Baihui (GV20) has shown therapeutic benefits for stroke patients. Given that natural killer (NK) cell infiltration into the brain significantly contributes to the exacerbation of cerebral
Externí odkaz:
https://doaj.org/article/f5382056bb724d50a4a606f7929a57d3
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Aim To elucidate the biological functionality and regulatory mechanisms of GdX in breast cancer (BC).Methods The examination of GdX expression in human BC tissues and cell lines was conducted through immunohistochemical (IHC) and Western blot. Cell p
Externí odkaz:
https://doaj.org/article/5fc84c59aee149298ca996e54e0883dc
Autor:
Tianyu Zhai, Liang Cai, Xi Jia, Mingfeng Xia, Hua Bian, Xin Gao, Chenling Pan, Xiaoying Li, Pu Xia
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102026- (2024)
Objective: Non-alcoholic fatty liver disease (NAFLD) is deemed as an emerging global epidemic, whereas the underlying pathogenic mechanism remains to be clarified. We aimed to systemically analyze all the NAFLD-related gene expression datasets from p
Externí odkaz:
https://doaj.org/article/91171bfc258742e8b4ef26786224e827
Autor:
Yu Pan, Lin Zhang, Wenjie Ma, Yassein M. Ibrahim, Wenli Zhang, Mengjie Wang, Xinrong Wang, Yunfei Xu, Caixia Gao, Hongyan Chen, He Zhang, Changyou Xia, Yue Wang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major thread to the global swine industry, lack of effective control strategies. This study explores the regulatory role of a small non-coding RNA, miR-191-5p, in PRRSV infection. We ob
Externí odkaz:
https://doaj.org/article/f1f759d71355455eaa36a42b30be43b5