Zobrazeno 1 - 10
of 348
pro vyhledávání: '"and Xiangdong Fang"'
Autor:
Yanxia Liu, Jie Liu, Shouwei Zhang, Jinyue Wang, Zhihong Sun, Huaibo Sun, Ying Yang, Guangmin Zheng, Yu Huang, Meng Li, Zhaojun Zhang, Jingfa Xiao, Changqing Zeng, Chengming Sun, Hongzhu Qu, Xiangdong Fang
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Circulating cell-free DNA (cfDNA) in the peripheral blood is a promising biomarker for cancer diagnosis and prognosis. Somatic mutations identified in cancers have been used to detect therapeutic targets for clinical transformation and indiv
Externí odkaz:
https://doaj.org/article/581c58582de848a69c249dc9519845d6
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Background and purpose The association of water loading with several infections remains unclear. Observational studies are hard to investigate definitively due to potential confounders. In this study, we employed Mendelian randomization (MR)
Externí odkaz:
https://doaj.org/article/9f4d3702d6ea4ab39bc7cfff49d57dd8
Autor:
Weilong Zou, Zhanjie Fang, Yu Feng, Shangjin Gong, Ziqiang Li, Meng Li, Yong Sun, Xiuyan Ruan, Xiangdong Fang, Hongzhu Qu, Haiyang Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Patients with primary multifocal hepatocellular carcinoma (HCC) have a poor prognosis and often experience a high rate of treatment failure. Multifocal HCC is mainly caused by intrahepatic metastasis (IM), and though portal vein t
Externí odkaz:
https://doaj.org/article/2ab88a413e504fe3ad1f9be2e847df9e
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Background Chronic kidney disease (CKD) lacks effective treatments and renal fibrosis (RF) is one of CKD’s outcomes. Dickkopf 3 (DKK3) has been identified as an agonist in CKD. However, the underlying mechanisms of DKK3 in CKD are not fully underst
Externí odkaz:
https://doaj.org/article/ad2bc8def7644ce9b904f13922ad89cb
Autor:
Rudan Xiao, Lijuan Zhang, Zijuan Xin, Junwei Zhu, Qian Zhang, Guangmin Zheng, Siyun Chu, Jing Wu, Lu Zhang, Yang Wan, Xiaojuan Chen, Weiping Yuan, Zhaojun Zhang, Xiaofan Zhu, Xiangdong Fang
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109172- (2024)
Summary: Energy metabolism in the context of erythropoiesis and related diseases remains largely unexplored. Here, we developed a primary cell model by differentiating hematopoietic stem progenitor cells toward the erythroid lineage and suppressing t
Externí odkaz:
https://doaj.org/article/1c3dedc8a58b4eaea167b715d2945b77
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1056-1069 (2023)
ABSTRACT Background Hyperglycemia accelerates the development of diabetic nephropathy (DN) by inducing renal tubular injury. Nevertheless, the mechanism has not been elaborated fully. Here, the pathogenesis of DN was investigated to seek novel treatm
Externí odkaz:
https://doaj.org/article/9d393098573c414e842c9b05fc31f5f3
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Nocturia is a manifestation of systemic diseases, in which chronic kidney disease (CKD) is an independent predictor of nocturia due to its osmotic diuretic mechanism. However, to our knowledge, previous studies have not examined the associat
Externí odkaz:
https://doaj.org/article/040ea9eb3d114e788093be379018473a
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 1, Pp 100019- (2024)
Background: Observational studies have shown an association between reduced renal function and the risk of sarcopenia. However, the causal relationship and the underlying biological mechanisms remain uncertain. Using a Mendelian randomization (MR) fr
Externí odkaz:
https://doaj.org/article/0c0228cee14e468b9e880fe820794b5d
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24872- (2024)
Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus. Periodontitis (PD) is a microbially-induced chronic inflammatory disease that is thought to have a bidirectional relationship with diabetes mellitus
Externí odkaz:
https://doaj.org/article/6d3bb7c7a1c346dda97a9947b0fc9a7e
Publikováno v:
Renal Failure, Vol 45, Iss 2 (2023)
Interferon regulatory factor 4 (IRF4) is expressed in immune cells and is a member of the interferon regulatory factor family. Recently, it has been found that IRF4 plays important roles in the acute kidney injury (AKI)-chronic kidney disease (CKD) t
Externí odkaz:
https://doaj.org/article/543b9ea23e2048edb90587600294fcd7