Zobrazeno 1 - 10
of 10
pro vyhledávání: '"and Shin-ichiro Mohri"'
Autor:
Kyoji Ando, Hiroshi Tsumuki, Koichiro Nishimura, Arata Yanagisawa, Taga Masashi, Shin-ichiro Mohri, Iwao Chujo, Tsuyoshi Taguchi, Toshiyuki Atsumi
Publikováno v:
Organic Process Research & Development. 15:376-381
A short and practical synthesis of the PDE4 inhibitor K-34 (1) was developed. This synthesis was achieved in four steps and with a 58% overall yield. The unique spiro acetal was created with except...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b62ed2550db08f9ff9410176407d5f58
https://doi.org/10.1021/op100291g
https://doi.org/10.1021/op100291g
Autor:
Tetsuya Nezu, Shin-ichiro Mohri, Koichiro Nishimura, Wakako Tamaki, Sachiko Kato, Ayako Maki, Eiichiro Imai, Arata Yanagisawa, Kyoji Ando
Publikováno v:
Organic Process Research & Development. 14:1182-1187
A practical and scalable synthesis of a PDE4 inhibitor KW-4490 (1) was developed. This improved synthesis features the construction of the 1-arylcyclohexene (9) by the Diels−Alder reaction followed by a newly established Bronsted acid-promoted hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb4ed6f0107ab8ddb6503e23f5f2f6b
https://doi.org/10.1021/op1001287
https://doi.org/10.1021/op1001287
Publikováno v:
Organic Letters. 11:5286-5289
Nonactivated arylalkenes are effectively converted to tertiary benzylic nitriles in the presence of triflic acid and trimethylsilyl cyanide. The hydrocyanation reactions result in good to excellent yield when electron-donating groups are substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3493fd4c178b6bb765ad80c420cccc
https://doi.org/10.1021/ol902244e
https://doi.org/10.1021/ol902244e
Autor:
Kenji Fujino, Yoshiaki Masuda, Iwao Chujo, Shin-ichiro Mohri, Masaji Kasai, Sachiko Kato, Takehiro Ogasa
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:3273-3286
The two new synthetic routes to 6,7-dihydro-10-fluoro-3-(2-fluorophenyl)-5H- benzo[6,7]cyclohepta[1,2-b]-quinoline-8-carboxylic acid (1), a novel immunosuppressant KF20444, are described. The seven-membered ring construction from 2-[4-(2-fluorophenyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c9fa93df1f93d171446273f48e0f50
https://doi.org/10.1016/s0968-0896(01)00238-3
https://doi.org/10.1016/s0968-0896(01)00238-3
Autor:
and Shin-ichiro Mohri, Hitoshi Takami, Masaji Kasai, Takehiro Ogasa, Kenji Fujino, Toshiyuki Atsumi
Publikováno v:
Organic Process Research & Development. 5:426-433
An efficient route suitable for a large-scale preparation of KF31327 (1), a potent phosphodiesterase V inhibitor, has been developed. We selected 7-chloro-2,4(1H,3H)-quinazolinedione (15) as a starting material, which gave the desired 6-nitro compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c044eba18508ee4c26c138395b1b805a
https://doi.org/10.1021/op010025y
https://doi.org/10.1021/op010025y
Publikováno v:
ChemInform. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ae161e9e604d0faad3f4de4eab94dd
https://doi.org/10.1002/chin.201013080
https://doi.org/10.1002/chin.201013080
Autor:
Shin-ichiro Mohri
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 59:514-515
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9536d0cc11a98fb539ab555be8067fa
https://doi.org/10.5059/yukigoseikyokaishi.59.514
https://doi.org/10.5059/yukigoseikyokaishi.59.514
Publikováno v:
The Journal of Organic Chemistry. 63:1746-1746
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c59a0b71c8f8fbd25d16fd27f52dfb3
https://doi.org/10.1021/jo974031x
https://doi.org/10.1021/jo974031x
Autor:
Arata Yanagisawa, Masashi Taga, Toshiyuki Atsumi, Koichiro Nishimura, Kyoji Ando, Tsuyoshi Taguchi, Hiroshi Tsumuki, Iwao Chujo, Shin-ichiro Mohri
Publikováno v:
Organic Process Research & Development; Mar2011, Vol. 15 Issue 2, p376-381, 6p
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :405
The regio- and stereo-selectivities in the [2 + 2] photocycloaddition of a series of 1-benzoylindoles with vinyl acetate and methyl acrylate have been investigated. With some exceptions, the 1 -benzoylindoles gave exclusively or predominantly the cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e69cb4451f55b9305c121850b59592
https://doi.org/10.1039/p19840000405
https://doi.org/10.1039/p19840000405