Zobrazeno 1 - 10
of 97
pro vyhledávání: '"and R. Andrew Byrd"'
Autor:
Varvara Folimonova, Xiang Chen, Hitendra Negi, Charles D. Schwieters, Jess Li, R. Andrew Byrd, Naomi Taylor, Philippe Youkharibache, Kylie J. Walters
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract T-cell therapies based on chimeric antigen receptor (CAR) targeting of a tumor-specific antigen offer hope for patients with relapsed or refractory cancers. CAR hinge and transmembrane regions link antigen recognition domains to intracellula
Externí odkaz:
https://doaj.org/article/b4c10e34cd6b426a9a8bdea815cc3474
Autor:
Yue Zhang, Olivier Soubias, Shashank Pant, Frank Heinrich, Alexander Vogel, Jess Li, Yifei Li, Luke A. Clifton, Sebastian Daum, Kirsten Bacia, Daniel Huster, Paul A. Randazzo, Mathias Lösche, Emad Tajkhorshid, R. Andrew Byrd
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract ADP-ribosylation factor 1 (Arf1) interacts with multiple cellular partners and membranes to regulate intracellular traffic, organelle structure and actin dynamics. Defining the dynamic conformational landscape of Arf1 in its active form, whe
Externí odkaz:
https://doaj.org/article/e58ab08c95164c4ba75fd58fe4fa9a1e
Autor:
Eric M Rosenberg, Xiaoying Jian, Olivier Soubias, Rebekah A Jackson, Erin Gladu, Emily Andersen, Lothar Esser, Alexander J Sodt, Di Xia, R Andrew Byrd, Paul A Randazzo
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0295103 (2024)
The ADP-ribosylation factors (Arfs) constitute a family of small GTPases within the Ras superfamily, with a distinguishing structural feature of a hypervariable N-terminal extension of the G domain modified with myristate. Arf proteins, including Arf
Externí odkaz:
https://doaj.org/article/c4416d823ace4476a1a0fe1b30cf19ce
Publikováno v:
Magnetic Resonance Letters, Vol 2, Iss 1, Pp 56-58 (2022)
Externí odkaz:
https://doaj.org/article/5c8f1d8ab54c41e3a786e5bbb1eaa9b1
Autor:
Christopher E Smith, Yien Che Tsai, Yu-He Liang, Domarin Khago, Jennifer Mariano, Jess Li, Sergey G Tarasov, Emma Gergel, Borong Tsai, Matthew Villaneuva, Michelle E Clapp, Valentin Magidson, Raj Chari, R Andrew Byrd, Xinhua Ji, Allan M Weissman
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001474 (2021)
Endoplasmic reticulum-associated degradation (ERAD) is a protein quality control pathway of fundamental importance to cellular homeostasis. Although multiple ERAD pathways exist for targeting topologically distinct substrates, all pathways require su
Externí odkaz:
https://doaj.org/article/1d1767c146ff4ca2be2d36cff2726f11
Autor:
Rashmi Agrata, Priyesh Mohanty, Aravind Ravichandran, Sanju Kumari, Nishant Varshney, GS Arun, Kanchan Chauhan, Jess Li, Kalyan S. Chakrabarti, R. Andrew Byrd, Ranabir Das
The deamidases secreted byBurkholderia pseudomalleiandEnteropathogenic Ecolimodify the residue 40 in ubiquitin from a Glutamine (Q) to Glutamate (E), triggering several downstream processes to cause cell cycle arrest and activate immune responses. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c155ad57c471d5ee10a7d8388d135ae
https://doi.org/10.1101/2023.05.22.541748
https://doi.org/10.1101/2023.05.22.541748
Autor:
Fa-An Chao, Srisathiyanarayanan Dharmaiah, Troy Taylor, Simon Messing, William Gillette, Dominic Esposito, Dwight V. Nissley, Frank McCormick, R. Andrew Byrd, Dhirendra K. Simanshu, Gabriel Cornilescu
Publikováno v:
Journal of the American Chemical Society. 144:4196-4205
KRAS is the most frequently mutated RAS protein in cancer patients, and it is estimated that about 20% of the cancer patients in the United States carried mutant RAS proteins. To accelerate therapeutic development, structures and dynamics of RAS prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbe756235a383749eb96cb807417c28
https://doi.org/10.1021/jacs.2c00007
https://doi.org/10.1021/jacs.2c00007
Autor:
Ian J. Fucci, R. Andrew Byrd
Publikováno v:
Protein Sci
Nuclear magnetic resonance (NMR) provides site specific information on local environments through chemical shifts. NMR is widely used in the study of proteins, ranging from determination of three-dimensional (3D) structures to characterizing dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0ed09095e9042d2f5e4c819a046301
https://doi.org/10.1002/pro.4181
https://doi.org/10.1002/pro.4181
Autor:
Clemens Anklin, R. Andrew Byrd
Publikováno v:
J Biomol NMR
Multi-resonance NMR experiments are powerful analytical and structural tools. Their conceptualization assumes that RF fields may be combined independently to manipulate spin interactions. However, practical implementation can compromise performance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36220d5d8bb1cd04a37b3b7dae8bbda5
https://doi.org/10.1007/s10858-021-00360-2
https://doi.org/10.1007/s10858-021-00360-2
Publikováno v:
J Biomol NMR
Recent methyl adiabatic relaxation dispersion experiments provide examination of conformational dynamics across a very wide timescale (10(2) – 10(5) sec(−1)) and, particularly, provide insight into the hydrophobic core of proteins and allosteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e3b098d5cb02f25088f0f819aeac49
https://doi.org/10.1007/s10858-020-00312-2
https://doi.org/10.1007/s10858-020-00312-2