Zobrazeno 1 - 10
of 154
pro vyhledávání: '"and Niamh Moran"'
Autor:
Cathy Breen, Jean O’Connell, Justin Geoghegan, Donal O’Shea, Susie Birney, Louise Tully, Karen Gaynor, Mark O’Kelly, Grace O’Malley, Clare O’Donovan, Oonagh Lyons, Mary Flynn, Suzanne Allen, Niamh Arthurs, Sarah Browne, Molly Byrne, Shauna Callaghan, Chris Collins, Aoife Courtney, Michael Crotty, Ciara Donohue, Caroline Donovan, Colin Dunlevy, Diarmuid Duggan, Naomi Fearon, Francis Finucane, Ita Fitzgerald, Siobhan Foy, John Garvey, Irene Gibson, Liam Glynn, Edward Gregg, Anne Griffin, Janas M. Harrington, Caroline Heary, Helen Heneghan, Andrew Hogan, Mary Hynes, Claire Kearney, Dervla Kelly, Karl Neff, Carel W. le Roux, Sean Manning, Fionnuala McAuliffe, Susan Moore, Niamh Moran, Maura Murphy, Celine Murrin, Sarah M. O’Brien, Caitríona O’Donnell, Sarah O’Dwyer, Cara O’Grada, Emer O’Malley, Orlaith O’Reilly, Sharleen O’Reilly, Olivia Porter, Helen M. Roche, Amanda Rhynehart, Leona Ryan, Suzanne Seery, Corina Soare, Ferrah Shaamile, Abigail Walsh, Catherine Woods, Conor Woods, Ruth Yoder
Publikováno v:
Obesity Facts, Pp 1-17 (2022)
Background: This Clinical Practice Guideline (CPG) for the management of obesity in adults in Ireland, adapted from the Canadian CPG, defines obesity as a complex chronic disease characterised by excess or dysfunctional adiposity that impairs health.
Externí odkaz:
https://doaj.org/article/8d2bd2ca2abf4933926993a11ba90621
Autor:
Shane P. Comer, Ana Le Chevillier, Paulina B. Szklanna, Sarah Kelliher, Khalid Saeed, Steven Cullen, Osasere Edebiri, Tiina O'Neill, Niamh Stephens, Luisa Weiss, Claire A. Murphy, Saraswathi Rajakumar, Alexandra Tierney, Conor Hughes, Áine Lennon, Niamh Moran, Patricia B. Maguire, Fionnuala Ní Áinle, Barry Kevane
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundVaccine-induced thrombotic thrombocytopenia (VITT) post SARS-CoV-2 vaccination is characterized by thrombocytopenia and severe thrombosis. Platelet function during patient recovery in the medium-/long-term has not been investigated fully. H
Externí odkaz:
https://doaj.org/article/e43da276dd40457692b1c34616144286
Autor:
Shane P Comer, Sarah Cullivan, Paulina B Szklanna, Luisa Weiss, Steven Cullen, Sarah Kelliher, Albert Smolenski, Claire Murphy, Haidar Altaie, John Curran, Katherine O'Reilly, Aoife G Cotter, Brian Marsh, Sean Gaine, Patrick Mallon, Brian McCullagh, Niamh Moran, Fionnuala Ní Áinle, Barry Kevane, Patricia B Maguire, COCOON Study investigators
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001109 (2021)
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and evidence of COVID-19-induced endot
Externí odkaz:
https://doaj.org/article/accff9fda6ad4f21a599f41124fa2796
Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome.
Autor:
Kevin T O'Brien, Kalyan Golla, Tilen Kranjc, Darragh O'Donovan, Seamus Allen, Patricia Maguire, Jeremy C Simpson, David O'Connell, Niamh Moran, Denis C Shields
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210337 (2019)
Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs) represent potential targets. Focal adhesions play a central role in adhesion by linking cells to the extracellular matrix. Integrins are central to this pr
Externí odkaz:
https://doaj.org/article/5d77b6ded1384de79e22ff89a22a2a4a
Publikováno v:
Royal Society Open Science, Vol 5, Iss 10 (2018)
The juxtamembrane domains (JMD) of transmembrane proteins are rich in critical peptide sequences that participate in dynamic cell signalling events. Synthetic JMD peptides derived from cadherin cell adhesion proteins have previously been shown to mod
Externí odkaz:
https://doaj.org/article/e655018e92cf49b6936dfcc111ddc4b0
Autor:
Aoife O'Connor, Jean-Noel Marsat, Annachiara Mitrugno, Tom Flahive, Niamh Moran, David Brayden, Marc Devocelle
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17559-17577 (2014)
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcome some of the limitations associated with peptides intended for therapeutic and/or diagnostic applications. Linear polymers such as poly(ethylene glyc
Externí odkaz:
https://doaj.org/article/7728e1f4b25c4f15917bbff0f789d0c4
Autor:
Federica Lombardi, Kalyan Golla, Darren J Fitzpatrick, Fergal P Casey, Niamh Moran, Denis C Shields
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004119 (2015)
Identifying effective therapeutic drug combinations that modulate complex signaling pathways in platelets is central to the advancement of effective anti-thrombotic therapies. However, there is no systems model of the platelet that predicts responses
Externí odkaz:
https://doaj.org/article/2addf7955fee48af83378f5240f6b09c
Autor:
Bridget Egan, Justin A. Kinsella, Joseph Harbison, Dermot Cox, George Hamilton, Dominick J. H. McCabe, Prakash Madhavan, Sinéad M. Murphy, T. Coughlan, Stephen J.X. Murphy, Sean O’Neill, Niamh Moran, Mary Paula Colgan, Sean Tierney, Soon Tjin Lim, Desmond O'Neill, Richard A. Walsh, D. R. Collins, T. M. Feeley
Publikováno v:
Thrombosis and Haemostasis. 119:821-833
Introduction Cerebral micro-embolic signals (MES) predict risk of stroke in carotid stenosis patients. However, MES-negative ‘recently symptomatic patients’ also have a higher stroke risk than ‘asymptomatic patients’. Differences in platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fdafd7ee2a7f07791551f501b40255
https://doi.org/10.1055/s-0039-1678666
https://doi.org/10.1055/s-0039-1678666
Autor:
Daniel K Shanley, Patrick A Kiely, Kalyan Golla, Seamus Allen, Kenneth Martin, Ronan T O'Riordan, Melanie Ball, John D Aplin, Bernhard B Singer, Noel Caplice, Niamh Moran, Tom Moore
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57491 (2013)
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and reach a concentration of up to
Externí odkaz:
https://doaj.org/article/36cc399900a842d09f227e777a1b78db
Autor:
David Williams, Alan G. Fahey, Fahad Buskandar, Simon A. McG. Thom, Kathleen Shortall, Jean Kennedy, Niamh Moran, Kirstyn James, Alice Stanton, Heather Hayes, Niall Pender, Thora El-Sayed, Eamon Dolan, Margaret M Brennan, Fiona O'Donovan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Diets low in seafood omega-3 polyunsaturated fatty acids (PUFAs) are very prevalent. Such diets have recently been ranked as the sixth most important dietary risk factor—1.5 million deaths and 33 million disability-adjusted life-years worldwide are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6338916713b8510dea95cc8fa6f872ea
http://europepmc.org/articles/PMC7508802
http://europepmc.org/articles/PMC7508802