Zobrazeno 1 - 1
of 1
pro vyhledávání: '"and Mark A. Nitz"'
Autor:
Christel Kronig, Mark R. Smit, Daugs Edward D, Christopher H. Hanson, Richard C. Lloyd, James A. Ramsden, Robert B. Appell, Matthew Willets, Mark A. Nitz, Matt Hansen, Céline Praquin, Lee T. Boulton, Louks David H, Helen Samuel, Jerry Heinrich
Publikováno v:
Organic Process Research & Development. 17:69-76
The synthesis of (S)-N-Boc-bis(4-fluorophenyl)alanine, an intermediate in the synthesis of denagliptin, is described from the synthesis of a 12 g proof of principle sample to a >900 kg cGMP manufacturing campaign. The chiral centre was established by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eaec36bb9d70d0de6857fe781770bc5
https://doi.org/10.1021/op3002855
https://doi.org/10.1021/op3002855
