Zobrazeno 1 - 10
of 21
pro vyhledávání: '"and Joanne Charlwood"'
Autor:
Bryan Winchester, Sarah Crook, Yves Blériot, Alexandra L. Lane, George W. J. Fleet, Joanne Charlwood, Christian F. Masaguer, David J. Watkin
Syntheses of the two epimeric 6C-methylglucoses from D-glucuronolactone rely on a non-stereoselective reduction of an intermediate lactol. A highly stereoselective reduction of a silylated lactol, which is accompanied by a silyl migration, gives easy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96671b74701aa3993235f370fdec8e8
https://ora.ox.ac.uk/objects/uuid:8a1649b9-51bc-4841-aa25-6a144b9fd75b
https://ora.ox.ac.uk/objects/uuid:8a1649b9-51bc-4841-aa25-6a144b9fd75b
Autor:
Patrick Camilleri, Peter G. Lord, Joanne Charlwood, Peter J. Bugelski, N. King, J. Mark Skehel, Uzma Atif
Publikováno v:
Journal of Proteome Research. 1:73-82
The regionally specific structure and function of the kidney renders it susceptible to toxic exposure. To characterize these changes at the proteome level, we have investigated the effects on protein expression following treatment with gentamicin.The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6892faad51a04d9363fd75261e1c8e35
https://doi.org/10.1021/pr0100063
https://doi.org/10.1021/pr0100063
Publikováno v:
Biomolecular Engineering. 18:229-240
The covalent attachment of carbohydrate to proteins is a very common co- or post-translational event in the biosynthesis of glycoproteins. The type and heterogeneity of these oligosaccharides can affect a range of physico-chemical and biological prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c945dcd9aa5244b0c17d83cc84de61
https://doi.org/10.1016/s1389-0344(01)00098-3
https://doi.org/10.1016/s1389-0344(01)00098-3
Publikováno v:
Biochemical and Biophysical Research Communications. 286:243-249
A recombinant IgG3 antibody with Phe-243 replaced by Ala (FA243) was expressed in a CHO-K1 parental cell line. The resulting IgG-Fc-linked carbohydrate was significantly alpha2,3-sialylated (53% of glycans), as indicated by normal- and reverse-phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d40b3538f044a6f092491f62c848aae
https://doi.org/10.1006/bbrc.2001.5382
https://doi.org/10.1006/bbrc.2001.5382
Publikováno v:
PROTEOMICS. 1:275-284
Human IgG and IgM, bovine IgM and three therapeutic IgG monoclonal antibodies have been separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis. Carbohydrates were then released from these immobilised proteins by direct enzymatic diges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dd7bada20d11f9ee231c3cc486e7d0
https://doi.org/10.1002/1615-9861(200102)1:2<275::aid-prot275>3.0.co
https://doi.org/10.1002/1615-9861(200102)1:2<275::aid-prot275>3.0.co
Publikováno v:
Analytical Chemistry. 72:1469-1474
A 1-mm microbore hydrophilic interaction column has been used for the separation of 2-aminoacridone (2-AMAC)-derivatized glycan mixtures, released from naturally occurring and recombinant proteins. Primary structure identification of the 2-AMAC glyca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d48c08f7f1a66b52ffa4e8d644c0fa1
https://doi.org/10.1021/ac991267n
https://doi.org/10.1021/ac991267n
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:1522-1530
2-Aminoacridone (2-AMAC) labelled N-linked glycan pools were analysed directly by a hybrid quadrupole orthogonal acceleration time-of-flight mass spectrometer (Q-Tof) in the precursor ion scanning and tandem mass spectrometry (MS/MS) modes. The use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19093ee953cba79b8cc4283a75b263d3
https://doi.org/10.1002/(sici)1097-0231(19990730)13:14<1522::aid-rcm684>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990730)13:14<1522::aid-rcm684>3.0.co
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:716-723
Oligosaccharides released from porcine thyroglobulin were first derivatised with 2-aminoacridone (2-AMAC) and analysed by capillary electrophoresis to determine the complexity of this glycan pool. The same glycan mixture was then subjected to either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d1438a094b3ec3aefc1010d56480fd
https://doi.org/10.1002/(sici)1097-0231(19990430)13:8<716::aid-rcm547>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990430)13:8<716::aid-rcm547>3.0.co
Publikováno v:
Analytical Chemistry. 71:102-108
A protocol has been developed involving the derivatization of glycan mixtures with 2-aminoacridone and co-injection with a dextran ladder derivatized with methyl 4-aminobenzoate (M-4AB). These two derivatizing agents have very different ultraviolet a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9684f17ba5f5f822c2b0b30f7868a7
https://doi.org/10.1021/ac9806759
https://doi.org/10.1021/ac9806759
Publikováno v:
Analytical Chemistry. 70:3840-3844
Reproducible microbore reversed-phase HPLC methodology has been developed, suitable for the analysis of carbohydrates derivatized with 2-aminoacridone. The high extinction coefficient of this label at around 260 nm, combined with the use of a new dio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b045ae1dda7899d1cf357ec9d8807901
https://doi.org/10.1021/ac980235h
https://doi.org/10.1021/ac980235h