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pro vyhledávání: '"and Jean L. Helom"'
Publikováno v:
Organic Process Research & Development. 2:407-411
An impurity in the initial scale-up batch of PDA-641 was identified and the pathway of its formation was established. The precursor of the impurity was formed by magnesium Meerwein-Ponndorf-Verley-Oppenauer reaction during the Grignard addition step.
Publikováno v:
Organic Process Research & Development; May2008, Vol. 12 Issue 4, p785-786, 2p