Zobrazeno 1 - 10
of 432
pro vyhledávání: '"and James F. Markmann"'
Autor:
Paria Mahboub, Mohamed Aburawi, O. Sila Ozgur, Casie Pendexter, Stephanie Cronin, Florence Min Lin, Rohil Jain, Murat N. Karabacak, Negin Karimian, Shannon N. Tessier, James F. Markmann, Heidi Yeh, Korkut Uygun
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
BackgroundDonation after circulatory death (DCD) grafts are vital for increasing available donor organs. Gradual rewarming during machine perfusion has proven effective in mitigating reperfusion injury and enhancing graft quality. Limited data exist
Externí odkaz:
https://doaj.org/article/b608a8f521794039a234323f9e0e0926
Autor:
Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois Lazeyras, Heidi Yeh, James F. Markmann, Korkut Uygun, Alejandro Ocampo, Sarah J. Mitchell, Florent Allagnat, Sébastien Déglise, Alban Longchamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Dietary restriction promotes resistance to surgical stress in multiple organisms. Counterintuitively, current medical protocols recommend short-term carbohydrate-rich drinks (carbohydrate loading) prior to surgery, part of a multimodal perio
Externí odkaz:
https://doaj.org/article/ffeaabec74c8436cb692b16a68581716
Autor:
Mohammadreza Mojoudi, McLean S. Taggart, Anil Kharga, Huyun Chen, Antonia T. Dinicu, Benjamin T. Wilks, James F. Markmann, Mehmet Toner, Shannon N. Tessier, Heidi Yeh, Korkut Uygun
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29519- (2024)
Background: Liver donation after cardiac death (DCD) makes up a small percentage of the organs used in transplantation and poses a higher risk of graft loss compared to donation after brain death (DBD); this is a result of ischemia reperfusion for wh
Externí odkaz:
https://doaj.org/article/bad439d98e9d4ac0b44a99548ad3eda6
Autor:
Alban Longchamp, MD, PhD, Fermin M. Fontan, MD, Mohamed M. Aburawi, MD, Corey Eymard, MD, Negin Karimian, MD, PhD, Danielle Detelich, MD, Casie Pendexter, BS, Stephanie Cronin, MS, Thomas Agius, MS, Sonal Nagpal, MBA, Peony Dutta Banik, BS, Shannon N. Tessier, PhD, Sinan Ozer, MBA, Francis L. Delmonico, MD, Korkut Uygun, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 4, p e1609 (2024)
Background. Brief normothermic machine perfusion is increasingly used to assess and recondition grafts before transplant. During normothermic machine perfusion, metabolic activity is typically maintained using red blood cell (RBC)–based solutions.
Externí odkaz:
https://doaj.org/article/396aa870c24442cab2483459c99fec7e
Autor:
Tsukasa Nakamura, MD, PhD, Richard Teo, MD, Angela R. Shih, MD, Katherine Latham, MD, Emily D. Bethea, MD, Sanjeeva Kalva, MD, Toshihide Tomosugi, MD, PhD, Takayuki Yamamoto, MD, PhD, Leigh Anne Dageforde, MD, MPH, Heidi Yeh, MD, Nahel Elias, MD, Adel Bozorgzadeh, MD, Tatsuo Kawai, MD, PhD, James F. Markmann, MD, PhD, Shoko Kimura, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 3, p e1594 (2024)
Externí odkaz:
https://doaj.org/article/0f0c7c4ab4d144f0843be40efb2cc64c
Autor:
Christian LeGuern, James F. Markmann
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/c6c5c74699be4488813932648029251f
Autor:
Daniel J. Firl, Grace Lassiter, Takayuki Hirose, Robert Policastro, Ashley D’Attilio, James F. Markmann, Tatsuo Kawai, Katherine C. Hall
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Porcine kidney xenotransplantation is accelerating towards clinical translation. However, despite the demonstrated ability of porcine kidneys to remove metabolic waste products, questions remain about their ability to faithfully recapitulate
Externí odkaz:
https://doaj.org/article/a3b4cf5831c441c8a2d3baadd8bd157d
Autor:
Thomas Agius, MS, Julien Songeon, MS, Arnaud Lyon, MD, Justine Longchamp, MD, Raphael Ruttimann, BS, Florent Allagnat, PhD, Sébastien Déglise, MD, Jean-Marc Corpataux, MD, Déla Golshayan, MD, PhD, Léo Buhler, MD, Raphael Meier, MD, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD, Korkut Uygun, PhD, Christian Toso, MD, PhD, Antoine Klauser, PhD, Francois Lazeyras, PhD, Alban Longchamp, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 11, p e1508 (2023)
Background. In rodents, hydrogen sulfide (H2S) reduces ischemia-reperfusion injury and improves renal graft function after transplantation. Here, we hypothesized that the benefits of H2S are conserved in pigs, a more clinically relevant model. Method
Externí odkaz:
https://doaj.org/article/62a376d8015c4df09588e2f10fda8ffe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
A subset of B-cells with tolerogenic functions, termed B-regulatory cells or Bregs, is characterized by the expression of anti-inflammatory/tolerogenic cytokines, namely IL-10, TGF-β, and IL-35, that contribute to their regulatory functions. Breg re
Externí odkaz:
https://doaj.org/article/884570e6af8047678574f591eee57356
Autor:
Francesca D’Addio, Anna Maestroni, Emma Assi, Moufida Ben Nasr, Giovanni Amabile, Vera Usuelli, Cristian Loretelli, Federico Bertuzzi, Barbara Antonioli, Francesco Cardarelli, Basset El Essawy, Anna Solini, Ivan C. Gerling, Cristina Bianchi, Gabriella Becchi, Serena Mazzucchelli, Domenico Corradi, Gian Paolo Fadini, Diego Foschi, James F. Markmann, Emanuela Orsi, Jan Škrha, Maria Gabriella Camboni, Reza Abdi, A. M. James Shapiro, Franco Folli, Johnny Ludvigsson, Stefano Del Prato, Gianvincenzo Zuccotti, Paolo Fiorina
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this new study the Authors demonstrated that the IGFBP3/TMEM219 pathway is a physiological regulator of pancreatic beta cell homeostasis and it is dysregulated in diabetes. IGFBP3/TMEM219 targeting may therefore serve as a therapeutic option in di
Externí odkaz:
https://doaj.org/article/691fd79ad7294c7890d97254a673270c