Zobrazeno 1 - 10
of 60
pro vyhledávání: '"and Ivan Lantos"'
Publikováno v:
International Journal of Peptide and Protein Research. 35:249-257
A convergent synthesis of the peptide [1-(β-mercapto-β,β-cyclopentamethylenepropionic acid)-2-(O-ethyl-d-tyrosine)-4-valine-9-desglycine]arginine vasopressin (1), based on the classical solution phase method, was developed. The molecule is assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d62a4286a3974f72685ec2d2e4e8872
https://doi.org/10.1111/j.1399-3011.1990.tb00945.x
https://doi.org/10.1111/j.1399-3011.1990.tb00945.x
Publikováno v:
Tetrahedron Letters. 41:5647-5651
(−)-Paroxetine hydrochloride was produced asymmetrically in seven steps starting from 4-fluorobenzaldehyde. The stereocenter at C-4 was initially set through desymmetrization of glutaric acid bis methyl ester 4 by PLE hydrolysis. A unique one-pot r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4cacc79c791f31ce9d86ad640fb2a5e
https://doi.org/10.1016/s0040-4039(00)00942-4
https://doi.org/10.1016/s0040-4039(00)00942-4
Publikováno v:
Organic Letters. 1:1839-1842
[formula: see text] The bakers' yeast reduction of 3-(1,3-benzodioxol-5-yl)-6-propoxy-1H-inden-1-one 4 has been shown to give (S)-3-(1,3-benzodioxol-5-yl)-2,3-dihydro-6-propoxy-1H-indan-1-one 6 in 65% yield with high enantioselectivity (> 99.0% ee),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99bfcb9484b0858994fa9886755a39f8
https://doi.org/10.1021/ol991111+
https://doi.org/10.1021/ol991111+
Autor:
K. Tubman, Chen T, Baresch K, Patel R, Banyard Af, Bernwieser I, Welz W, Blanka M, Mayrhofer G, Bhatnagar Pradip, Leitner K, Baumgartner H, Stevenson D, Hiebl J, Ivan Lantos, Alberts Dp, Esch Pm, Karin Winkler, Rovenszky F, Hermann Kollmann, Weihtrager H, Kjell Undheim, Bodenteich M, Rio A
Publikováno v:
The Journal of Peptide Research. 54:54-65
Linear and convergent routes for the large-scale preparation of the hematoregulatory nonapeptide (Glp-Glu-Asp)2-DAS-(Lys)2 (2, SK&F 107647) were investigated. A convergent approach ('3 + 2'-route employing Boc-and benzyl ester protecting groups) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38be0cedab65714316c4d500bfe20c33
https://doi.org/10.1034/j.1399-3011.1999.00089.x
https://doi.org/10.1034/j.1399-3011.1999.00089.x
Autor:
Wilf Mendelson, Ivan Lantos, Ravi Shanker Garigipati, Karl Erhardt, Richard T. Matsuoka, Ken Tubman, wei-Yuan Zhang, Steve Ross, Lynn Marie Tucker, Jerry L. Adams, Margaret E. Sorenson, Liu Li, Joseph R. Flisak, David Stevenson
Publikováno v:
The Journal of Organic Chemistry. 62:5385-5391
An enantioselective synthesis of chiral hydroxyurea based 5-lipoxygenase inhibitors is reported via a five-step sequence in about 30% overall yield. The synthesis is based on a novel tandem nucleop...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa220986ef490aa7a308ce2507c703f
https://doi.org/10.1021/jo9621736
https://doi.org/10.1021/jo9621736
Autor:
Li Liu, J. R. Flisak, Ivan Lantos, Richard T. Matsuoka, Lynn Marie Tucker, Wilford Mendelson, A. J. Villani, Wei Yuan Zhang
Publikováno v:
Tetrahedron Letters. 37:4639-4642
An enantioselective synthesis of a 5-LO inhibiting chiral hydroxyurea is described based on the nucleophilic addition of dimethylsulfoxonium ylide to a nitrone bearing a mannose-derived chiral auxiliary. The dihydrobenzofuran skeleton is then constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26e2fa1df39810618e3486595ec6923
https://doi.org/10.1016/0040-4039(96)00922-7
https://doi.org/10.1016/0040-4039(96)00922-7
Autor:
wei-Yuan Zhang, Ivan Lantos
Publikováno v:
Tetrahedron Letters. 35:5977-5980
Condensation of ketone derived nitrones with N-methylcarboximidoyl chloride affords after hydrolytic workup α-amidoketones. The results are interpreted in terms of the formation of an intermediate capable of undergoing a facile [3,3] sigmatropic rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e22fb62b5d04f4f26e9674ef1ba02ed
https://doi.org/10.1016/0040-4039(94)88053-0
https://doi.org/10.1016/0040-4039(94)88053-0
Publikováno v:
The Journal of Organic Chemistry. 58:7092-7095
A novel synthetic approach to heterocycles containing the imidazole moiety based on the multihetero-Cope rearrangement is described. Oximes are reacted with benzenecarboximidoyl chlorides 4 affording adducts that readily undergo the hetero-Cope rearr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27768bbffe935a512bf5e89e4a7a8220
https://doi.org/10.1021/jo00077a033
https://doi.org/10.1021/jo00077a033
Autor:
David B. Staiger, Lendon N. Pridgen, Michael Anthony Mcguire, Louisa Lam Davis, Drake S. Eggleston, Ivan Lantos, S. C. Shilcrat, Lee Webb
Publikováno v:
Journal of Heterocyclic Chemistry. 30:1663-1671
The ethyl chloroformate salts of a variety of benzo-fused six membered π-deficient heteroaromatics, including quinoline, isoquinoline, 4-chloroquinoline, 3-bromoquinoline, phthalazine, and quinazoline, reacted with 6-aryl-2,3-dihydroimidazo[2,1-b]th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1368b2982588106121b22344666a526a
https://doi.org/10.1002/jhet.5570300634
https://doi.org/10.1002/jhet.5570300634
Autor:
Joseph R. Flisak, Alvydas Alfonsas Jarmas, Lawrence Snyder, Kerry Gombatz, Vance J. Novack, Wilford Mendelson, Ivan Lantos, James J. Remich, Monica M. Holmes
Publikováno v:
The Journal of Organic Chemistry. 58:6247-6254
A highly efficient and enantioselective (>99.5% ee) synthesis of the title compound has been accomplished. Key steps include (1) epoxidation of unsaturated ketone 7 in the presence of a polyamino acid to afford compound 8 in >95 ee, (2) regioselectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb26daba5f6d9f62168a9e6b95f5491d
https://doi.org/10.1021/jo00075a019
https://doi.org/10.1021/jo00075a019