Zobrazeno 1 - 10
of 318
pro vyhledávání: '"and I. Tucker"'
Autor:
Norah G. Verbout, Christina U. Lorentz, Brandon D. Markway, Michael Wallisch, Thomas C. Marbury, Enrico Di Cera, Joseph J. Shatzel, András Gruber, Erik I. Tucker
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The protein C system regulates blood coagulation, inflammation, and vascular integrity. AB002 is an injectable protein C activating enzyme under investigation to safely prevent and treat thrombosis. In preclinical models, AB002 is
Externí odkaz:
https://doaj.org/article/de9625889c004a0a9813402404b9f1bc
Autor:
Joseph J. Shatzel, Emma P. DeLoughery, Christina U. Lorentz, Erik I. Tucker, Joseph E. Aslan, Monica T. Hinds, David Gailani, Jeffrey I. Weitz, Owen J. T. McCarty, Andras Gruber
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 500-505 (2020)
Abstract Coronavirus disease 2019 (COVID‐19) is predicted to overwhelm health care capacity in the United States and worldwide, and, as such, interventions that could prevent clinical decompensation and respiratory compromise in infected patients a
Externí odkaz:
https://doaj.org/article/a59e582344824c618e4a5df1c66f6ef4
Autor:
Irmandy Wicaksono, Carson I. Tucker, Tao Sun, Cesar A. Guerrero, Clare Liu, Wesley M. Woo, Eric J. Pence, Canan Dagdeviren
Publikováno v:
npj Flexible Electronics, Vol 4, Iss 1, Pp 1-13 (2020)
Abstract The rapid advancement of electronic devices and fabrication technologies has further promoted the field of wearables and smart textiles. However, most of the current efforts in textile electronics focus on a single modality and cover a small
Externí odkaz:
https://doaj.org/article/f45bf4c9d34548ab9de3c3a526543098
Autor:
Michael Wallisch, Christina U. Lorentz, Hari H. S. Lakshmanan, Jennifer Johnson, Marschelle R. Carris, Cristina Puy, David Gailani, Monica T. Hinds, Owen J. T. McCarty, András Gruber, Erik I. Tucker
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 2, Pp 205-216 (2020)
Abstract Background The contact factor XII (FXII) activates upon contact with a variety of charged surfaces. Activated FXII (FXIIa) activates factor XI, which activates factor IX, resulting in thrombin generation, platelet activation, and fibrin form
Externí odkaz:
https://doaj.org/article/1f99c210012946a3a755e743573f891d
Autor:
Toshiaki Shirai, Alexey S. Revenko, Justin Tibbitts, Anh T.P. Ngo, Annachiara Mitrugno, Laura D. Healy, Jennifer Johnson, Erik I. Tucker, Monica T. Hinds, Lisa M. Coussens, Owen J.T. McCarty, Brett P. Monia, András Gruber
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3080-3091 (2019)
Abstract: In humans, platelet count within the normal range is required for physiological hemostasis, but, adversely, platelets also support pathological thrombosis. Moreover, by releasing growth factors, they may enhance neoplastic proliferation. We
Externí odkaz:
https://doaj.org/article/4c4e4254f9bf4a1ba88e8704d6fc1b2e
Autor:
Maxim Litvak, Aleksandr Shamanaev, Sandip Zalawadiya, Anton Matafonov, Anton Kobrin, Edward P. Feener, Michael Wallisch, Erik I. Tucker, Owen J.T. McCarty, David Gailani
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1200-1213
Autor:
Christina U. Lorentz, Norah G. Verbout, Zhiping Cao, Lijuan Liu, Monica T. Hinds, Owen J.T. McCarty, Ivan Ivanov, Erik I. Tucker, David Gailani, András Gruber
Publikováno v:
Blood Advances, Vol 2, Iss 2, Pp 85-88 (2018)
Externí odkaz:
https://doaj.org/article/b60d992154bb4a649a7315543477f23f
Autor:
Kelley R. Jordan, Cory R. Wyatt, Meghan E. Fallon, Randy Woltjer, Edward A. Neuwelt, Quifang Cheng, David Gailani, Christina Lorentz, Erik I. Tucker, Owen J.T. McCarty, Monica T. Hinds, Khanh P. Nguyen
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2035-2045
Deep vein thrombosis (DVT) and post-thrombotic syndrome (PTS) remain highly prevalent despite modern medical therapy. Contact activation is a promising target for safe antithrombotic anticoagulation. The anti-factor XI (FXI) monoclonal antibody 14E11
Autor:
Michael A Pfeffer, Helen Vu, Tia CL Kohs, Jenny Wang, Christina U Lorentz, Erik I Tucker, Sven R Olson, Thomas G Deloughery, Monica T Hinds, Owen JT McCarty, Joseph J Shatzel
Publikováno v:
Blood. 140:1247-1249
Autor:
Norah G Verbout, Weiping Su, Peter Pham, Kelley Jordan, Tia CL Kohs, Erik I Tucker, Owen JT McCarty, Larry S Sherman
Objective: Relapses in patients with relapsing-remitting multiple sclerosis (RRMS) are typically treated with high-dose corticosteroids including methylprednisolone. However, high-dose corticosteroids are associated with significant adverse effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7aec55878f828eb974f415cbe635e50
https://doi.org/10.21203/rs.3.rs-2802415/v1
https://doi.org/10.21203/rs.3.rs-2802415/v1