Zobrazeno 1 - 10
of 168
pro vyhledávání: '"and Francis J. Schmitz"'
Publikováno v:
Journal of natural products. 80(1)
A new anthranilic acid derivative (1) was isolated from a Philippine sponge, Oscarella stillans (Bergquist and Kelly). The structure of compound 1, named oscarellin, was determined as 2-amino-3-(3′-aminopropoxy)benzoic acid from spectroscopic data
Autor:
JangJa Hong, Noriyasu Hirasawa, Ok Pyo Zee, Hirokazu Sasaki, Kenji Ishihara, Jong Hwan Kwak, Toshio Seyama, Francis J. Schmitz, Kazuo Ohuchi
Publikováno v:
Planta Medica. 75:1494-1498
Effects of artekeiskeanol A, a newly isolated coumarin derivative from Artemisa keiskeana Miq. (Compositae), the extract of which is used for treatment of rheumatoid arthritis as a folk medicine, on the antigen-induced activation of RBL-2H3 cells wer
Publikováno v:
Journal of Natural Products. 67:1415-1418
Three new chlorinated diterpenes, 6-8, along with five known ones, 1-5, were isolated from the molluscs Pleurobranchus albiguttatus and P. forskalii collected in the Philippines. These diterpenes are presumably metabolites of a Lissoclinum species of
Autor:
Nathaniel L. Segraves, Frederick A. Valeriote, Halina Pietraszkiewicz, Sarah J. Robinson, Sadri A Said, Francis J. Schmitz, Xiong Fu, Phillip Crews, Daniel Garcia
Publikováno v:
Journal of Natural Products. 67:783-792
The fascaplysin class of compounds have been further investigated from six organisms consisting of four sponge collections (Fascaplysinopsis reticulata) and two tunicate collections (Didemnum sp.). This work is an extension of an earlier communicatio
Autor:
Tyler A. Johnson, Suzette Lopez, Phillip Crews, Frederick A. Valeriote, Sadri A Said, Xiong Fu, Halina Pietraszkiewicz, Francis J. Schmitz, Nathaniel L. Segraves
Publikováno v:
Tetrahedron Letters. 44:3471-3475
The structural variations and bioactivity properties of the alkaloids in the fascaplysin (1) and the reticulatine (3) families were examined. Four organisms were analyzed consisting of two collections of the sponge Fascaplysinopsis reticulata and two
Publikováno v:
Tetrahedron. 59:1349-1357
Synthesis of the cytotoxic isoquinoline quinone perfragilin A, an improved synthesis of perfragilin B and preparation of some analogues of both these compounds are described. Cytotoxicity evaluation of a number of the products is reported. The regios
Publikováno v:
Journal of Natural Products. 65:704-708
Twelve new briarane diterpenes, designated milolides (1-12), and one known diterpene, 9-deacetylstylatulide lactone (13), were isolated from the Micronesian octocoral Briareum stechei collected at Yap, Federated States of Micronesia. Their structures
Publikováno v:
Tetrahedron. 56:8989-8993
Six new propionate-derived metabolites, 4–9, have been isolated along with the known 9,10-deoxytridachione (1) from the sacoglossan mollusc Placobranchus ocellatus collected in the Philippines. The structures of the new compounds were determined by
Publikováno v:
Journal of Natural Products. 63:1153-1156
Two new sesquiterpenes, pelorol (1) and 5-epi-smenospongine (2), and seven known ones (3-9) were isolated from the sponge Petrosaspongia metachromia, collected from Yap, Federated States of Micronesia. Their structures were determined from spectral d
Autor:
Tara L. McCready, Hue A. Luu, Bonnieca Islam, Charles F.B. Holmes, John F. Dawson, Francis J. Schmitz
Publikováno v:
Journal of Biological Chemistry. 275:4192-4198
Site-directed mutagenesis was used to investigate the mechanism of interaction between the catalytic subunit of human protein phosphatase-1 (PP-1cgamma) and members of the calyculin family of toxins. Clavosines A and B are related to calyculins but a