Zobrazeno 1 - 10
of 69
pro vyhledávání: '"and Francesca Paganelli"'
Autor:
Francesca Chiarini, Francesca Paganelli, Tommaso Balestra, Cristina Capanni, Antonietta Fazio, Maria Cristina Manara, Lorena Landuzzi, Stefania Petrini, Camilla Evangelisti, Pier-Luigi Lollini, Alberto M. Martelli, Giovanna Lattanzi, Katia Scotlandi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract Lamin A, a main constituent of the nuclear lamina, is involved in mechanosignaling and cell migration through dynamic interactions with the LINC complex, formed by the nuclear envelope proteins SUN1, SUN2 and the nesprins. Here, we investiga
Externí odkaz:
https://doaj.org/article/5d5b516d43e64786927cb4086677f8b3
Autor:
Silvia Lampis, Salvatore Raieli, Luca Montemurro, Damiano Bartolucci, Camilla Amadesi, Sonia Bortolotti, Silvia Angelucci, Anna Lisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Sabrina Valente, Matthias Fischer, Alberto Maria Martelli, Gianandrea Pasquinelli, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Neuroblastoma is a deadly childhood cancer, and MYCN-amplified neuroblastoma (MNA-NB) patients have the worst prognoses and are therapy-resistant. While retinoic acid (RA) is beneficial for some neuroblastoma patients, the cause o
Externí odkaz:
https://doaj.org/article/57da51d707e148518d41d12e01cff92a
Autor:
Alberto M. Martelli, Francesca Paganelli, Serena Truocchio, Carla Palumbo, Francesca Chiarini, James A. McCubrey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2962 (2023)
The Hedgehog (HH) signaling network is one of the main regulators of invertebrate and vertebrate embryonic development. Along with other networks, such as NOTCH and WNT, HH signaling specifies both the early patterning and the polarity events as well
Externí odkaz:
https://doaj.org/article/e59cadd6d6984543b109ab90c46f5c22
Autor:
Alberto M. Martelli, Francesca Paganelli, Camilla Evangelisti, Francesca Chiarini, James A. McCubrey
Publikováno v:
Cells, Vol 11, Iss 11, p 1812 (2022)
Glycogen synthase kinase-3 (GSK-3) is an evolutionarily conserved, ubiquitously expressed, multifunctional serine/threonine protein kinase involved in the regulation of a variety of physiological processes. GSK-3 comprises two isoforms (α and β) wh
Externí odkaz:
https://doaj.org/article/bb961d77fbac48859cbd25d9fd809e37
Autor:
Francesca Paganelli, Francesca Chiarini, Annalisa Palmieri, Marcella Martinelli, Paola Sena, Jessika Bertacchini, Luca Roncucci, Alessandra Cappellini, Alberto M. Martelli, Massimo Bonucci, Carla Fiorentini, Ivano Hammarberg Ferri
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1325 (2021)
The AHCC standardized extract of cultured Lentinula edodes mycelia, and the standardized extract of Asparagus officinalis stem, trademarked as ETAS, are well known supplements with immunomodulatory and anticancer potential. Several reports have descr
Externí odkaz:
https://doaj.org/article/409689d81ef540368c5c423a35be007a
Autor:
Sonia Bortolotti, Silvia Angelucci, Luca Montemurro, Damiano Bartolucci, Salvatore Raieli, Silvia Lampis, Camilla Amadesi, Annalisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Francesca Chiarini, Gabriella Teti, Mirella Falconi, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 990
Volume 15
Issue 3
Pages: 990
Small-cell lung cancer (SCLC) is the most aggressive lung cancer type, and is associated with smoking, low survival rate due to high vascularization, metastasis and drug resistance. Alterations in MYC family members are biomarkers of poor prognosis f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6aa28f2fa1936adbf7088a18489a9e4
Autor:
Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi
Publikováno v:
Cells, Vol 9, Iss 3, p 774 (2020)
A type lamins are fundamental components of the nuclear lamina. Changes in lamin A expression correlate with malignant transformation in several cancers. However, the role of lamin A has not been explored in osteosarcoma (OS). Here, we wanted to inve
Externí odkaz:
https://doaj.org/article/9cfa258b67404b31b16e33f93be44379
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1098 (2020)
Acute lymphoblastic leukemia (ALL) is an aggressive hematologic neoplastic disorder that arises from the clonal expansion of transformed T-cell or B-cell precursors. Thanks to progress in chemotherapy protocols, ALL outcome has significantly improved
Externí odkaz:
https://doaj.org/article/07f62906c7514564b25ba8df45e595b7
Autor:
Francesca Chiarini, Camilla Evangelisti, Vittoria Cenni, Antonietta Fazio, Francesca Paganelli, Alberto M. Martelli, Giovanna Lattanzi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 847 (2019)
The mechanistic target of rapamycin (mTOR) is a ubiquitous serine/threonine kinase that regulates anabolic and catabolic processes, in response to environmental inputs. The existence of mTOR in numerous cell compartments explains its specific ability
Externí odkaz:
https://doaj.org/article/d2bb0a8bd72e4bac9083eb72197533ac
Publikováno v:
Italian Journal of Animal Science, Vol 4, Iss 3, Pp 282-286 (2010)
Mycoplasma gallisepticum (MG) continues to be an important pathogen of poultry, causing significant production losses in many parts of the world. Eradication is the preferred method of control but it could result impractical after the organism has be
Externí odkaz:
https://doaj.org/article/40f5a8aaf738424eb9933ec940e38811