Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Autor: Babine Robert E, Edward L. Brown, David A. Matthews, Susan L. Binford, Stephen T. Worland, Shella A. Fuhrman, Amy K. Patick, James E. V. Harr, Reich Siegfried Heinz, Joseph T. Marakovits, Thomas J. Prins, Caroline A. Lee, Wallace Michael B, Peter S. Dragovich, Littlefield Ethel S, and Dorothy M. DeLisle, James W. Meador, Rose Ann Ferre, Clifford E. Ford, Ru Zhou, Stephen E. Webber, Jayashree Tikhe

Publikováno v: Journal of Medicinal Chemistry. 41:2819-2834

The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are described. These compounds are comprised of an ethyl propenoate Michael acceptor moiety and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ae4560588b9aa6544425b6ac69eedc
https://doi.org/10.1021/jm9800696

Contributors

Autor: Barbara L. Asselin, Georgianne Arnold, Sherry L. Bayliff, Christopher E. Belcher, Deena Berkowitz, Jeffrey Blake, Christopher F. Bolling, Deborah Borchers, Brittanny Liam Boulanger, Peter N. Bowers, Paula K. Braverman, Carmelita V. Britton, Robert A. Broughton, Ann Buchanan, Gale R. Burstein, James R. Campbell, Kathleen M. Campbell, Lynn R. Campbell, Margaret‐Ann Carno, Patrick L. Carolan, Mary T. Caserta, Heidi A. Castillo, Kathryn Castle, Peter Chang, Sharon F. Chen, Eulalia R.Y. Cheng, Elizabeth K. Cherot, Patricia R. Chess, Olivia Chiang, Barbara A. Chini, Jill M. Cholette, Cynthia Christy, Emma Ciafaloni, Carolyn Cleary, Lisa Loeb Colton, Gregory P. Conners, Heidi V. Connolly, Stephen Cook, Christopher Copenhaver, Elliott L. Crow, Therese Cvetkovich, David Cywinski, Kristen Smith Danielson, Dorothy M. Delisle, Larry Denk, Lee A. Denson, George T. Drugas, Carolyn Piver Dukarm, Jason G. Emmick, Gus Gibbons Emmick, Oscar Escobar, Anna F. Fakadej, Richard A. Falcone, S. Nichole Feeney, Thomas J. Fischer, Donna J. Fisher, Amy Fix, Chin‐To Fong, Cynthia L. Fox, D. Steven Fox, Robert J. Freishtat, Madelyn Garcia, Lynn C. Garfunkel, Matthew D. Gearinger, Mary Ellen Gellerstedt, John Girotto, Michelle A. Grenier, Alka Goyal, Maryellen E. Gusic, Caroline B. Hall, Jill S. Halterman, David W. Hannon, William G. Harmon, J. Peter Harris, Amy Heneghan, Neil E. Herendeen, Joeli Hettler, John L. Hick, Andrea S. Hinkle, Alejandro Hoberman, Christopher H. Hodgman, Allison L. Holm, Mark A. Hostetler, Cynthia R. Howard, Stephanie Sansoni Hsu, William C. Hulbert, Robert Humphreys, Jon Hutchinson, Susan Hyman, Carolyn Jacobs Parks, Andree Jacobs‐Perkins, Sandra H. Jee, Nicholas Jospe, Steven Joyce, Jeffrey M. Kaczorowski, Indra Kancitis, James W. Kendig, John Knight, David N. Korones, Peter A. Kouides, Richard Kreipe, Diana Barnett Kudes, Jennifer M. Kwon, Marc S. Lampell, Meredith Landorf, Nancy E. Lanphear, Jeffrey H. Lee, Lucia H. Lee, Thomas J.A. Lehman, Paul Lehoullier, Norma B. Lerner, Gregory S. Liptak, Ann M. Loeffler, K. Makoroff, Elizabeth Mannick, Christina M. Mccann, Carol A. Mccarthy, Michael E. Mcconnell, Alan M. Mendelsohn, Ram K. Menon, Robert A. Mevorach, Ayesa N. Mian, Heather Michalak, Daniel E. Miga, Nicole L. Mihalopoulos, Jonathan W. Mink, M. Susan Moyer, Suzanne Fredrickson Mullin, Charles M. Myer, Ran Namgung, Jonathan F. Nasser, Robert Needlman, Joseph A. Nicholas, Maureen Novak, Samuel Nurko, Craig Orlowski, Ponrat Pakpreo, James Palis, Murray H. Passo, Joanne Pedro‐Carroll, Walter Pegoli, Karen S. Powers, Susan Haller Psaila, Ronald Rabinowitz, Marc A. Raslich, Karen L. Resch, Meredith E. Reynolds, Matthew Richardson, Brett Robbins, Mark Roddy, Dennis Roy, Leticia Manning Ryan, Sheryl A. Ryan, Stanley J. Schaffer, Lora L. Schauer, Charles Schubert, George J. Schwartz, Steven Scofield, George B. Segel, Edgard A. Segura, Lorna M. Seybolt, Nader Shaikh, Ronald L. Sham, Laura Jean Shipley, Benjamin L. Shneider, David M. Siegel, Mark Scott Smith, R. Dennis Steed, Moira A. Szilagyi, Susanne E. Tanski, Danielle Thomas‐Taylor, Svetlana Tisma‐Dupanovic, John J. Treanor, C. Elizabeth Trefts, William T. Tsai, Reginald Tsang, Elise W. Van Der Jagt, Jon A. Vanderhoof, William S. Varade, Kathleen M. Ventre, Michael K. Visick, Brad W. Warner, Geoffrey A. Weinberg, Melanie Wellington, David R. White, Susan Wiley, Robert R. Wittler, Bryan J. Wolhwend, Jonathan P. Wood, Kimberly A. Workowski, Daniel Yawman, Roger A. Yeager, Rosemary J. Young

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::714c6b84075e08c30d31d8385aa3b97d
https://doi.org/10.1016/b978-032303506-4.10363-3

A microtechnique for neutrophil respiratory burst oxidase in a cell-free system--characterization of oxidase activation system

Autor: Dorothy M. DeLisle, Shigenobu Umeki

Publikováno v: Comparative biochemistry and physiology. B, Comparative biochemistry. 96(3)

1. 1. A microtechnique for quantitating human neutrophil NADPH oxidase in a cell-free system is described. 2. 2. This spectrophotometric discontinuous (fixed time) method is less material-consuming than existing methods and is more useful for experim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1d0cbc463535d693537fddab6f3d3c
https://pubmed.ncbi.nlm.nih.gov/2390859