Zobrazeno 1 - 10
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pro vyhledávání: '"and Donald J. Knoechel"'
Publikováno v:
Organic Process Research & Development. 21:763-770
A novel setup to analyze the heat of reaction of different single- and multiphase reactions carried out in continuous flow is presented. The measurement principle of the calorimetric system is based on true heat flow measurements and therefore ensure
Publikováno v:
Organic Process Research & Development. 12:989-994
Perchloric acid appears unique in its ability to catalyze stereoselective trans-acetalizations of steroids. However, the requisite recipes result in an intermediate phase enriched in perchlorate and organic material with the potential for catastrophi
Autor:
Mike Hawksworth, Derek L. Tickner, Richard W. Barnhart, Ying Kang, Brian Moon, Stephen M. Shaw, Taber Geraldine Patricia, Paul Higginson, David J. Dale, Jerry D. Clark, Gerald A. Weisenburger, Donald J. Knoechel
Publikováno v:
Organic Process Research & Development. 11:1112-1125
The heat of reaction is an important parameter in the safe, successful scale-up of chemical processes. Reaction heat data is used to calculate the potential adiabatic temperature rise of the desire...
Publikováno v:
Organic Process Research & Development. 1:217-221
Reactions of steroid 3,5-dienol acetates with electrophilic fluorinating reagents of the N-fluoro quaternary salt class were examined for the purpose of selecting a reagent for use in commercial scale synthesis. The neutral N-fluorosulfonimides gave
Autor:
Moses W. McMillan, Perrault William R, William Watt,§ and, Donald J. Knoechel, Lori A. LaPean, Mark A. Krook, Gerald N. Evenson, Pearlman Bruce Allen, Mark A. Lyster, K. Paul Shephard, Paul J. Dobrowolski
Publikováno v:
Organic Process Research & Development. 1:106-116
A practical synthesis of atevirdine mesylate, Pharmacia & Upjohn's first-generation non-nucleoside reverse transcriptase (RT) inhibitor for treatment of AIDS, is described. The route consists of three steps. In the first step, the starting material,
Autor:
Donald J. Knoechel
Publikováno v:
Organic Process Research & Development. 5:668-669
Publikováno v:
Organic Process Research & Development; Aug2008, Vol. 12 Issue 5, p989-994, 6p
Autor:
Gerald A. Weisenburger, Richard W. Barnhart, Jerry D. Clark, David J. Dale, Mike Hawksworth, Paul D. Higginson, Ying Kang, Donald J. Knoechel, Brian S. Moon, Stephen M. Shaw, Geraldine P. Taber, Derek L. Tickner
Publikováno v:
Organic Process Research & Development; Oct2007, Vol. 11 Issue 6, p1112-1125, 14p
Autor:
Nancy F. Cole, Elizabeth A. Fiore, Thomas J. Smith, Donald J. Knoechel, Daniel R. Derringer, Rebecca K. Schmitt
Publikováno v:
Inorganic Chemistry. 24:1978-1982
Les reactions du titre conduisent aux complexes de type Mo 2 Cl 4 (LL) 2 . On etudie egalement les reactions de Mo 2 Cl 4 (py) 4 et Mo 2 Cl 4 (P(n-Pr) 3 ) 4 avec dppe et dppp
Autor:
Donald J. Knoechel, Thomas Zeitlow, Thomas M. Blok, Robert W. Carlson, Kurt D. Kaufman, Dennis J. Erb, Lincoln Mcbride
Publikováno v:
Journal of Heterocyclic Chemistry. 19:1051-1056
Several psoralen derivatives have been synthesized in order to evaluate their efficacy as photochemotherapeutic (PUVA) agents, including a variety of 4′-substituted-4,5′,8-trimethypsoralen compounds (1d-j). Improved synthesis of the very potent p