Zobrazeno 1 - 10
of 20
pro vyhledávání: '"and Charalambos Camoutsis"'
Autor:
Georgios Charitos, Dimitrios T. Trafalis, Panayiotis Dalezis, Constantinos Potamitis, Vasiliki Sarli, Panagiotis Zoumpoulakis, Charalambos Camoutsis
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4784-4794 (2019)
The development of new antitumor agents is one of the most pressing research areas in medicinal chemistry and medicine. The importance of triazole and thiadiazole rings as scaffolds present in a wide range of therapeutic agents has been well reported
Externí odkaz:
https://doaj.org/article/7701a1630fc541fdb94cb7f91e8ecc27
Autor:
Vasiliki Sarli, Constantinos Potamitis, Panayiotis Dalezis, Charalambos Camoutsis, Georgios Charitos, Panagiotis Zoumpoulakis, Dimitrios T. Trafalis
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4784-4794 (2019)
The development of new antitumor agents is one of the most pressing research areas in medicinal chemistry and medicine. The importance of triazole and thiadiazole rings as scaffolds present in a wide range of therapeutic agents has been well reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13274bc863187497f2c7de598e79e48
https://doi.org/10.1016/j.arabjc.2016.09.015
https://doi.org/10.1016/j.arabjc.2016.09.015
Publikováno v:
ISRN Hematology
This prospective study assessed the quality of life of patients with homozygous transfusion-dependent beta-thalassemia in Greece receiving three different iron chelation treatments. Patients enrolled were receiving one of the following chelation ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f51003d8de8c7d7f5ed2ff0d708e86d
https://doi.org/10.5402/2012/139862
https://doi.org/10.5402/2012/139862
Publikováno v:
Melanoma Research. 15:273-281
Evidence indicating that hybrid steroid compounds of anti-cancer agents produce reduced toxicity, significantly lower than the cytotoxic components alone, and increased anti-cancer activity has prompted the design and development of such steroids, mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116dd8131b06902526db09c2113abe51
https://doi.org/10.1097/00008390-200508000-00007
https://doi.org/10.1097/00008390-200508000-00007
Autor:
Charalambos Camoutsis
Publikováno v:
Journal of Heterocyclic Chemistry. 33:539-557
In recent years the interest of this investigator has been attracted to a series of new compounds in which a cyclopentanoperhydrophenanthrene system is condensed with various heterocyclic rings. As was to be expected, the addition of heterocycles to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b4b2385e1cfa78eabfc68292d431ac
https://doi.org/10.1002/jhet.5570330303
https://doi.org/10.1002/jhet.5570330303
Autor:
George D, Geromichalos, Elena, Geromichalou, Charalambos, Camoutsis, Michael, Kontos, Panagiotis, Dalezis, Athanasios, Papageorgiou, Anastasios A, Grivas, Christos, Tsigris, Dimitrios T, Trafalis
Publikováno v:
Anticancer research. 31(3)
In order to reduce toxicity and to enhance anticancer activity of nitrogen mustards, three hybrid steroidal esters were synthesized and tested in vitro against human pancreatic cancer cells expressing uridine phosphorylase (UPase). The inhibition pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5168b161e8818bde4d3844a7e4982ad1
https://pubmed.ncbi.nlm.nih.gov/21498703
https://pubmed.ncbi.nlm.nih.gov/21498703
Publikováno v:
ChemInform. 31
The synthesis of the isomeric D-homoazasteroido[3,2-c]- (3) and -[2,3-d]lisoxazoles (4) and A-homoazasteroido[17,16-c]isoxazole (6) are reported by the reaction of 2-hydroxymethylene-17α-aza-D-homo-5α-androstan-3,17-dione (2) and 16-hydroxymethylen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2301a1193145cf7a011aabeb8deb6ddb
https://doi.org/10.1002/chin.200011220
https://doi.org/10.1002/chin.200011220
Autor:
Michael C. Kontos, Catherine Koukoulitsa, P Karamanakos, Dimitrios T. Trafalis, George D. Geromichalos, Elias Bastounis, Marilena Nikolopoulou, J Charalambos Camoutsis
Publikováno v:
Oncology research. 16(3)
In order to further improve the toxicity profile and the anticancer effect of chlorambucil (CBL), we have synthesized a new estrone D-lactam steroidal ester of CBL (ESBL). The aim of this study was to investigate the in vitro activity of ESBL against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1354293b1eac988cfdb23788dd8f37
https://pubmed.ncbi.nlm.nih.gov/16925114
https://pubmed.ncbi.nlm.nih.gov/16925114
Autor:
George D. Geromichalos, Charalambos Camoutsis, Dimitrios T. Trafalis, P Karamanakos, Athanasios A. Papageorgiou, Catherine Koukoulitsa
Publikováno v:
Breast cancer research and treatment. 97(1)
The sensitivity of breast neoplasms to hormonal control provides the basis of novel investigational treatments with steroidal alkylators. An androsterone D-lactam steroidal ester, the 3beta-hydroxy-13alpha-amino-13,17-seco- 5alpha-androstan-17-oic-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4b493ea724539eb864fab095f4cb4c
https://pubmed.ncbi.nlm.nih.gov/16319980
https://pubmed.ncbi.nlm.nih.gov/16319980
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 60(10)
The p-[N,N-bis(2-chloroethyl)amino]phenylacetic acid esters of hecogenin and aza-homo-hecogenin have been prepared and their antineoplastic activity was evaluated against two basic drug screening systems in rodents, P388 lymphocytic and L1210 lymphoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014c6052ee8746a80adac87a1c6a0260
https://pubmed.ncbi.nlm.nih.gov/16139280
https://pubmed.ncbi.nlm.nih.gov/16139280