Zobrazeno 1 - 10
of 100
pro vyhledávání: '"and Arie Zask"'
Autor:
Hengrui Liu, Sho Iketani, Arie Zask, Nisha Khanizeman, Eva Bednarova, Farhad Forouhar, Brandon Fowler, Seo Jung Hong, Hiroshi Mohri, Manoj S. Nair, Yaoxing Huang, Nicholas E. S. Tay, Sumin Lee, Charles Karan, Samuel J. Resnick, Colette Quinn, Wenjing Li, Henry Shion, Xin Xia, Jacob D. Daniels, Michelle Bartolo-Cruz, Marcelo Farina, Presha Rajbhandari, Christopher Jurtschenko, Matthew A. Lauber, Thomas McDonald, Michael E. Stokes, Brett L. Hurst, Tomislav Rovis, Alejandro Chavez, David D. Ho, Brent R. Stockwell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Small molecule drugs promise to remain a valuable tool in controlling the ongoing COVID-19 pandemic. Here the authors describe optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for potential treatment of COVID-19.
Externí odkaz:
https://doaj.org/article/ca1887901eef4f3082b30b23a613d463
Autor:
Sho Iketani, Farhad Forouhar, Hengrui Liu, Seo Jung Hong, Fang-Yu Lin, Manoj S. Nair, Arie Zask, Yaoxing Huang, Li Xing, Brent R. Stockwell, Alejandro Chavez, David D. Ho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
The essential SARS-CoV-2 3CL protease is of interest as a drug target. Here, the authors identify three 3CL inhibitors and characterize them both in vitro and with a cell-based assay, and they also present the inhibitor-bound 3CL crystal structures,
Externí odkaz:
https://doaj.org/article/26f785c3852741599e99fcbeb5f6eb0e
Autor:
Sho Iketani, Farhad Forouhar, Hengrui Liu, Seo Jung Hong, Fang-Yu Lin, Manoj S. Nair, Arie Zask, Yaoxing Huang, Li Xing, Brent R. Stockwell, Alejandro Chavez, David D. Ho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-23082-3
Externí odkaz:
https://doaj.org/article/82ec3060aff24d5ab09af11137ccc875
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Supplementary Figure from Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b33ea786d0742501a13c41a69c7ef44
https://doi.org/10.1158/2159-8290.22542057
https://doi.org/10.1158/2159-8290.22542057
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Low-intensity maintenance therapy with 6-mercaptopurine (6-MP) limits the occurrence of acute lymphoblastic leukemia (ALL) relapse and is central to the success of multiagent chemotherapy protocols. Activating mutations in the 5′-nucleotidase cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724879d7d04346e020351611ac3bd15b
https://doi.org/10.1158/2159-8290.c.6549792.v1
https://doi.org/10.1158/2159-8290.c.6549792.v1
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Supplementary Table from Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b1347dacb24bff35508410f812e7e2
https://doi.org/10.1158/2159-8290.22542048.v1
https://doi.org/10.1158/2159-8290.22542048.v1
Autor:
Arie Zask, Pawel Nowak, Robert T. Abraham, James J. Gibbons, Tarek S. Mansour, Semiramis Ayral-Kaloustian, John Ellingboe, Derek C. Cole, David J. Malwitz, Kevin Curran, Jeroen Verheijen, Jamie Kim, Boris Shor, Judy Lucas, Wei-Guo Zhang, Celine Shi, Lourdes Toral-Barza, Ker Yu
Supplementary Methods, Figures 1-2, Tables 1-2 from Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5af9a5271aa0276274bef18b48d37d
https://doi.org/10.1158/0008-5472.22378673.v1
https://doi.org/10.1158/0008-5472.22378673.v1
Autor:
Clara Reglero, Chelsea L. Dieck, Arie Zask, Farhad Forouhar, Anouchka P. Laurent, Wen-Hsuan W. Lin, Robert Albero, Hannah I. Miller, Cindy Ma, Julie M. Gastier-Foster, Mignon L. Loh, Liang Tong, Brent R. Stockwell, Teresa Palomero, Adolfo A. Ferrando
Publikováno v:
Cancer Discov
Low-intensity maintenance therapy with 6-mercaptopurine (6-MP) limits the occurrence of acute lymphoblastic leukemia (ALL) relapse and is central to the success of multiagent chemotherapy protocols. Activating mutations in the 5′-nucleotidase cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993ed9dee959ca6c9f9a09886a4b291b
https://europepmc.org/articles/PMC9633388/
https://europepmc.org/articles/PMC9633388/
Publikováno v:
Chirality. 32:632-651
In this brief review on Koji Nakanishi's remarkable career in natural products chemistry, we have highlighted a number of his accomplishments that illustrate the broad diversity of his interests. These include the isolation, structure determination,
Publikováno v:
Fundamentals of Supramolecular Chirality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4c6ad258404f115d63af28036ad984c
https://doi.org/10.1142/9781800610255_0003
https://doi.org/10.1142/9781800610255_0003