Zobrazeno 1 - 10
of 375
pro vyhledávání: '"and Anne J. Ridley"'
Autor:
Siau Wei Bai, Maria Teresa Herrera-Abreu, Jennifer L Rohn, Victor Racine, Virginia Tajadura, Narendra Suryavanshi, Stephanie Bechtel, Stefan Wiemann, Buzz Baum, Anne J Ridley
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/359fb156db4d4c7399c52e248f393f9a
Autor:
Camilla Cerutti, Serena Lucotti, Sofia T. Menendez, Nicolas Reymond, Ritu Garg, Ignacio A. Romero, Ruth Muschel, Anne J. Ridley
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113989- (2024)
Summary: Attachment of circulating tumor cells to the endothelial cells (ECs) lining blood vessels is a critical step in cancer metastatic colonization, which leads to metastatic outgrowth. Breast and prostate cancers are common malignancies in women
Externí odkaz:
https://doaj.org/article/18472507ce70468fbc218518cb422c60
Autor:
Jennifer C. Coleman, Luke Tattersall, Val Yianni, Laura Knight, Hongqiang Yu, Sadie R. Hallett, Philip Johnson, Ana J. Caetano, Charlie Cosstick, Anne J. Ridley, Alison Gartland, Maria R. Conte, Agamemnon E. Grigoriadis
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109288- (2024)
Summary: RNA-binding proteins (RBPs) are emerging as important regulators of cancer pathogenesis. We reveal that the RBPs LARP4A and LARP4B are differentially overexpressed in osteosarcoma and osteosarcoma lung metastases, as well as in prostate canc
Externí odkaz:
https://doaj.org/article/e05b9197d6e846339a41025635e63f0c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The Rho GTPase family consists of 20 genes encoding intracellular signalling proteins that influence cytoskeletal dynamics, cell migration and cell cycle progression. They are implicated in breast cancer progression but their role in breast
Externí odkaz:
https://doaj.org/article/88de764cce624b03b9cf1775e8f78e0b
Autor:
Fabiola González-Herrera, Natasha S. Clayton, Daniela Guzmán-Rivera, Ileana Carrillo, Christian Castillo, Mabel Catalán, Renatto Anfossi, Helena Quintero-Pertuz, María Elena Quilaqueo, Claudio Olea-Azar, Mario Rivera-Meza, Ulrike Kemmerling, Anne J. Ridley, Raúl Vivar, Juan Diego Maya
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionChronic Chagasic cardiomyopathy (CCC), caused by the protozoan Trypanosoma cruzi, is the most severe manifestation of Chagas disease.CCC is characterized by cardiac inflammation and fibrosis caused by a persistent inflammatory response. F
Externí odkaz:
https://doaj.org/article/0be090d4f1914ee4ae40ee38765d5d98
Autor:
Natasha S. Clayton, Anne J. Ridley
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
As key regulators of cytoskeletal dynamics, Rho GTPases coordinate a wide range of cellular processes, including cell polarity, cell migration, and cell cycle progression. The adoption of a pro-migratory phenotype enables cancer cells to invade the s
Externí odkaz:
https://doaj.org/article/596ee592015e4110b68596d57ef188c4
Publikováno v:
BMC Cell Biology, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Endothelial cells provide a barrier between blood and tissues, which is regulated to allow molecules and cells in out of tissues. Patients with cerebral cavernous malformations (CCM) have dilated leaky blood vessels, especially in
Externí odkaz:
https://doaj.org/article/8c97f250e71a424e884d90ae35cf8aa1
Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1551-1561 (2018)
Abstract: CD38 is a transmembrane exoenzyme that is associated with poor prognosis in chronic lymphocytic leukemia (CLL). High CD38 levels in CLL cells are linked to increased cell migration, but the molecular basis is unknown. CD38 produces nicotini
Externí odkaz:
https://doaj.org/article/1d24606429b04e50a18a254e18ae60f3
Autor:
Virginia Tajadura-Ortega, Ritu Garg, Richard Allen, Claudia Owczarek, Michael D. Bright, Samuel Kean, Aisyah Mohd-Noor, Anita Grigoriadis, Timothy C. Elston, Klaus M. Hahn, Anne J. Ridley
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-20 (2018)
Abstract Background Cell migration is essential for development and tissue repair, but it also contributes to disease. Rho GTPases regulate cell migration, but a comprehensive analysis of how each Rho signalling component affects migration has not be
Externí odkaz:
https://doaj.org/article/ff58e5f3ece74db8839b003b8eba8180
Publikováno v:
Cancer Medicine, Vol 5, Iss 11, Pp 3353-3367 (2016)
Abstract Cancer survival rates are increasing, and as a result, more cancer survivors are exposed to the risk of developing a second primary cancer (SPC). It has been hypothesized that one of the underlying mechanisms for this risk could be mediated
Externí odkaz:
https://doaj.org/article/6532cb6caddd487cb122c583b6dc3c41