Zobrazeno 1 - 10
of 65
pro vyhledávání: '"and Andrew M. Bray"'
Autor:
Rustum S. Boyce, Jonathan M. White, Andrew M. Bray, Ian W. James, Craig S. Sheehan, Thao Nguyen, Sharon T. Marino, Beata M. Krywult, Daniel A. Huggins, Peter G. Griffiths, Neil Choi, Danuta Stachurska-Buczek, Jack G. Parsons
Publikováno v:
Molecules, Vol 9, Iss 6, Pp 449-458 (2004)
The synthesis of (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methoxyphenyl)- propionic acid, (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methylphenyl)propionic acid and (2S)-2-benzyl-oxymethyl-3-(2,4-dimethylphenyl)propionic acid has been achieved by TiCl4 mediate
Externí odkaz:
https://doaj.org/article/79972dc0ed9743ebba6459a5f9db9f31
Autor:
Rustum S. Boyce, Jonathan M. White, Andrew M. Bray, Ian W. James, Peter G. Griffiths, Jack G. Parsons, Neil Choi, Thao Nguyen, Craig S. Sheehan, Beata M. Krywult, Daniel A. Huggins, Danuta Stachurska-Buczek, Sharon T. Marino
Publikováno v:
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for
Externí odkaz:
https://doaj.org/article/4608ad3d215d4a5baa43da91d5408ca6
Publikováno v:
International Journal of Peptide and Protein Research. 42:384-391
Recent developments in multiple peptide synthesis have made it feasible to synthesize and screen large numbers of peptide analogs simultaneously. We report here a model study of large scale screening of stereoisomers of substance P with systematic d-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa729bbb39431edcd8db478962a97d2f
https://doi.org/10.1111/j.1399-3011.1993.tb00509.x
https://doi.org/10.1111/j.1399-3011.1993.tb00509.x
Publikováno v:
International Journal of Peptide and Protein Research. 42:392-399
Recent developments in multiple peptide synthesis have made it feasible to synthesize and screen large numbers of peptide analogs simultaneously. We report here a model study of large scale screening of stereoisomers of substance P with systematic D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98221b40aa0d607e8cbb869ff42630ff
https://doi.org/10.1111/j.1399-3011.1993.tb00510.x
https://doi.org/10.1111/j.1399-3011.1993.tb00510.x
Publikováno v:
Journal of Peptide Science. 12:525-532
Methodology is described here for the efficient parallel synthesis and cyclization of linear peptide libraries using intramolecular S-alkylation chemistry in combination with Multipin solid phase peptide synthesis (Multipin SPPS). The effective use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30077f0a406ad90ff2ba83dc94af3009
https://doi.org/10.1002/psc.761
https://doi.org/10.1002/psc.761
Autor:
Susan James, Zemin Wu, P. G. Griffiths, Kyoko Fujimoto, Akihiko Okuyama, Satoru Ikegami, Tatsuhiro Harada, Andrew M. Bray, Yoichiro Hoshina, Michael Lilly
Publikováno v:
Tetrahedron Letters. 46:9035-9038
2,3-Diphenylpropionic acid library for VLA-4 antagonist was synthesized on solid-phase. Comparison of the two synthetic routes via an orthogonal generation of two aromatic amino functional groups are discussed. From this work, several compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9bae07ade8a35d0b546d5f6a4eb749
https://doi.org/10.1016/j.tetlet.2005.10.087
https://doi.org/10.1016/j.tetlet.2005.10.087
Autor:
Daniel A. Huggins, Jonathan M. White, Sharon T. Marino, Peter G. Griffiths, Andrew M. Bray, Thao Nguyen, Ian W. James, Craig S. Sheehan, Beata Krywult, Danuta Stachurska-Buczek, Neil Choi, Rustum S. Boyce, Jack G. Parsons
Publikováno v:
Molecules
Volume 9
Issue 6
Pages: 405-426
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
Volume 9
Issue 6
Pages: 405-426
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6533a0c8e4bedc60da13723a3d4922
https://doi.org/10.3390/90600405
https://doi.org/10.3390/90600405
Publikováno v:
Journal of Peptide Science. 10:659-665
A new method for the synthesis of cyclic head-to-side chain peptide libraries has been developed in which the key cyclization step involves reaction between a C-terminal ketone and an N-terminal hydroxylamine to form a macrocyclic oxime. This methodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8b485a1e76c16ac4edeea6661494fc
https://doi.org/10.1002/psc.575
https://doi.org/10.1002/psc.575
Autor:
Michael C. Fitzgerald, Rhonda Campbell, Phil Riley, Nicholas J. Ede, Francesca Ercole, K. R. A. Samankumara Sandanayake, Zemin Wu, Senake Perera, Philip Rea, and Andrew M. Bray, Marc N. Mathieu, Yen Pham
Publikováno v:
Journal of Combinatorial Chemistry. 5:166-171
Solid-phase synthesis is greatly dependent on the solid support. Here, we report the use of a new hydrophilic grafted surface on SynPhase lanterns in solid-phase organic chemistry. A convenient and facile solid-phase synthesis of disubstituted 1,4-be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bec6a6cd2d73afbf099ad4e9be1184
https://doi.org/10.1021/cc020057c
https://doi.org/10.1021/cc020057c
Publikováno v:
Journal of Combinatorial Chemistry. 5(4):414-428
A solid-phase combinatorial synthesis approach toward the cyclic depsipeptide aurilide (1) and related analogues is described. The peptide moiety 2 was assembled on trityl linker-functionalized SynPhase Crowns using an Fmoc strategy. Optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ba20eb84690c7a84b4179b5d9bdf70
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100488450
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100488450