Zobrazeno 1 - 10 of 25 pro vyhledávání: '"and Andrew A. Raubitschek"'
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Data from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Autor: Russell E. Jacobs, Andrew A. Raubitschek, David Colcher, Daniel Procissi, Hargun Sohi, David Wert, Thomas S.C. Ng
Purpose: Targeted nanotherapies are being developed to improve tumor drug delivery and enhance therapeutic response. Techniques that can predict response will facilitate clinical translation and may help define optimal treatment strategies. We evalua
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5baf68f297c0fe6a6192a9eccc2431
https://doi.org/10.1158/1078-0432.c.6521297
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3
Supplementary Figure 1 from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Autor: Russell E. Jacobs, Andrew A. Raubitschek, David Colcher, Daniel Procissi, Hargun Sohi, David Wert, Thomas S.C. Ng
PDF file - 64K, Boxplots of cellular proliferation rates for different treatment groups calculated by applying ADC data to a logistic model of tumor growth. Boxplots for (A) control, (B) CRLX101 and (C) CPT-11 animals between day 0/2, day 0/4, day 2/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aba66e39d6a0c706404f519fccb593e
https://doi.org/10.1158/1078-0432.22448078
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5
Supplementary Figure 2 from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Autor: Russell E. Jacobs, Andrew A. Raubitschek, David Colcher, Daniel Procissi, Hargun Sohi, David Wert, Thomas S.C. Ng
PDF file - 112K, Quantitative histological assessment of CRLX101 and CPT-11 response. Tumors treated with CRLX101 (5 mg/kg), CPT-11 (100 mg/kg) or saline were harvested for histology on days 0, 2, 4, and 7. Tumor samples were subsequently sectioned a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b3aa1bb1f72bd5e596b6cd8eb77739
https://doi.org/10.1158/1078-0432.22448075.v1
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7
Akademický článek
Low Dose Focused Ultrasound Induces Enhanced Tumor Accumulation of Natural Killer Cells.
Autor: Naomi S Sta Maria, Samuel R Barnes, Michael R Weist, David Colcher, Andrew A Raubitschek, Russell E Jacobs
Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142767 (2015)
Natural killer (NK) cells play a vital antitumor role as part of the innate immune system. Efficacy of adoptive transfer of NK cells depends on their ability to recognize and target tumors. We investigated whether low dose focused ultrasound with mic
Externí odkaz: https://doaj.org/article/ed5c8b8e177b431ea42c9d8f2525a32f
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8
Tumor Uptake of
Autor: Joanne E, Mortimer, James R, Bading, Jinha M, Park, Paul H, Frankel, Mary I, Carroll, Tri T, Tran, Erasmus K, Poku, Russell C, Rockne, Andrew A, Raubitschek, John E, Shively, David M, Colcher
Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 59(1)
The goal of this study was to characterize the relationship between tumor uptake of 64Cu-DOTA-trastuzumab as measured by PET/CT and standard, immunohistochemistry (IHC)-based, histopathologic classification of human epidermal growth factor receptor 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::96558cca7b97abbac5a5beac3a007fe1
https://pubmed.ncbi.nlm.nih.gov/29553697
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9
Reduction of Kidney Uptake in Radiometal Labeled Peptide Linkers Conjugated to Recombinant Antibody Fragments. Site-Specific Conjugation of DOTA-Peptides to a Cys-Diabody
Autor: Tove Olafsen, Anne-Line Anderson, John E. Shively, Lin Li, and Andrew A. Raubitschek, Anna M. Wu
Publikováno v: Bioconjugate Chemistry. 13:985-995
Arano and co-workers (Arano et al. (1999) Cancer Res. 59, 128-134) have synthesized peptides with an N-terminal radioiodinated hippuric acid and a C-terminal lysine linked to antibody fragments via the epsilon-amino group of lysine that show reduced
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbb11f0b900a3524ed23aa993b490a2
https://doi.org/10.1021/bc025565u
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10
Vinyl Sulfone Bifunctional Derivatives of DOTA Allow Sulfhydryl- or Amino-Directed Coupling to Antibodies. Conjugates Retain Immunoreactivity and Have Similar Biodistributions
Autor: John E. Shively, Shih-wa Tsai, and Andrew A. Raubitschek, Anne-Line Anderson, Lin Li, David A. Keire
Publikováno v: Bioconjugate Chemistry. 13:110-115
We have synthesized a bifunctional vinyl sulfone-cysteineamido derivative of DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) that can be conjugated to the sulfhydryls of mildly reduced recombinant antibody (chimeric anti-CEA antibody
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5aa3d98e1dc5fa1dfe3dd780261816
https://doi.org/10.1021/bc015535b
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