Zobrazeno 1 - 10
of 94
pro vyhledávání: '"and Andrei Surguchov"'
Publikováno v:
Molecules, Vol 24, Iss 2, p 305 (2019)
Synucleins are small naturally unfolded proteins involved in neurodegenerative diseases and cancer. The family contains three members: α-, β-, and -synuclein. α-Synuclein is the most thoroughly investigated because of its close association with Pa
Externí odkaz:
https://doaj.org/article/7e36cc3fcee04a209eb783e392751f5f
Autor:
Andrei Surguchov, Alexei A. Surguchev
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3899 (2024)
Epidemiological evidence points to an inverse association between Parkinson’s disease (PD) and almost all cancers except melanoma, for which this association is positive. The results of multiple studies have demonstrated that patients with PD are a
Externí odkaz:
https://doaj.org/article/641b15c732294478ac4974e4143abb64
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1215 (2023)
For a long time, studies of amyloidogenic proteins and peptides (amyloidogenic PPs) have been focused basically on their harmful properties and association with diseases. A vast amount of research has investigated the structure of pathogenic amyloids
Externí odkaz:
https://doaj.org/article/d557d112ddfc45dc879d446f7998ed43
Autor:
Andrei Surguchov
Publikováno v:
Brain Sciences, Vol 13, Iss 1, p 150 (2023)
Synucleinopathies are a group of neurodegenerative diseases with common pathological lesions associated with the excessive accumulation and abnormal intracellular deposition of toxic species of α-synuclein. The shared clinical features are chronic p
Externí odkaz:
https://doaj.org/article/223de067ea5f4abe855527dc851ecdc3
Autor:
Andrei Surguchov, Alexei Surguchev
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3241 (2022)
The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer. The current number of publications on synucleins has exceeded 16.000
Externí odkaz:
https://doaj.org/article/d94fbf8343844d7fadb274c4740e4dee
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 624 (2021)
Synucleinopathies are a group of neurodegenerative diseases characterized by the accumulation of α-synuclein aggregates in neurons, nerve fibers or glial cells. Three main types of diseases belong to the synucleinopathies: Parkinson’s disease, dem
Externí odkaz:
https://doaj.org/article/2a35c43ec12a4324bfb2733011aeb1a3
Autor:
Andrei Surguchov
Publikováno v:
Cells, Vol 10, Iss 2, p 407 (2021)
Parkinson’s disease (PD) is the second most common neurodegenerative disease, afflicting ~10 million people worldwide. Although several genes linked to PD are currently identified, PD remains primarily an idiopathic disorder. Neuronal protein α-sy
Externí odkaz:
https://doaj.org/article/7d4b3d41519f47bcb64afe9e09bb35cb
Autor:
Andrei Surguchov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2801 (2020)
α-Synuclein is a naturally unfolded protein which easily aggregates and forms toxic inclusions and deposits. It is associated with several neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multipl
Externí odkaz:
https://doaj.org/article/b359fefda0624063ab9cc4093101d594
Autor:
Andrei Surguchov
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Externí odkaz:
https://doaj.org/article/6e98cfaae61b41ba815e6e18faef8249
Publikováno v:
Biology, Vol 8, Iss 2, p 43 (2019)
The variety of lifespans of different organisms in nature is amazing. Although it is acknowledged that the longevity is determined by a complex interaction between hereditary and environmental factors, many questions about factors defining lifespan r
Externí odkaz:
https://doaj.org/article/83733fb5ebac4f9590b3606a71fb1aa1