Zobrazeno 1 - 10
of 143
pro vyhledávání: '"and Andrea Trabocchi"'
Autor:
Matteo Lulli, Andrea Trabocchi, Giandomenico Roviello, Martina Catalano, Laura Papucci, Astrid Parenti, Alice Molli, Cristina Napoli, Ida Landini, Nicola Schiavone, Andrea Lapucci
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ovarian cancer is the deadliest gynaecologic malignancies worldwide. Platinum based chemotherapy is the mainstay treatment for ovarian cancer; however, frequent recurrence and chemoresistance onset in patients with advanced diseases remain a therapeu
Externí odkaz:
https://doaj.org/article/17364d656bb54ab9a6043e79d5869c66
Autor:
Suzanne Willems, Elena Detta, Lorenzo Baldini, Deniz Tietz, Andrea Trabocchi, Andreas Brunschweiger
Publikováno v:
ACS Omega, Vol 9, Iss 7, Pp 7719-7724 (2024)
Externí odkaz:
https://doaj.org/article/0fc1a17b13864c3b868bf35798a39123
Autor:
Alessia De Santis, Deborah Grifagni, Andrea Orsetti, Elena Lenci, Antonio Rosato, Mariapina D’Onofrio, Andrea Trabocchi, Simone Ciofi-Baffoni, Francesca Cantini, Vito Calderone
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1260 (2024)
The conservation of the main protease in viral genomes, combined with the absence of a homologous protease in humans, makes this enzyme family an ideal target for developing broad-spectrum antiviral drugs with minimized host toxicity. GC-376, a pepti
Externí odkaz:
https://doaj.org/article/e9ef22ae83444f268486edbe5fa60502
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 200-211 (2020)
The Cu-catalyzed multicomponent ketone–amine–alkyne (KA2) reaction was combined with a Pauson–Khand cycloaddition to give access of unprecedented constrained spirocyclic pyrrolocyclopentenone derivatives following a DOS couple-pair approach. Th
Externí odkaz:
https://doaj.org/article/0aa7afa4c3e1487491a29a93936e3d22
Autor:
Caterina Dallari, Riccardo Innocenti, Elena Lenci, Andrea Trabocchi, Francesco Saverio Pavone, Caterina Credi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5573 (2022)
Surface-enhanced Raman spectroscopy (SERS) exploiting Raman reporter-labeled nanoparticles (RR@NPs) represents a powerful tool for the improvement of optical bio-assays due to RRs’ narrow peaks, SERS high sensitivity, and potential for multiplexing
Externí odkaz:
https://doaj.org/article/4d286246757d45fe89d1cd321728c74e
Publikováno v:
Molecules, Vol 27, Iss 4, p 1249 (2022)
During tumor angiogenesis different growth factors, cytokines and other molecules interact closely with each other to facilitate tumor cell invasion and metastatic diffusion. The most intensively studied as molecular targets in anti-angiogenic therap
Externí odkaz:
https://doaj.org/article/9ae161f977c24005851b7c0d3de5e7c1
Publikováno v:
The Journal of Organic Chemistry. 87:12041-12051
The development of molecules able to target protein-protein interactions (PPIs) is of interest for the development of novel therapeutic agents. Since a high percentage of PPIs are mediated by α-helical structure at the interacting surface, peptidomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f010c9cde736e86fb638def9a161d413
https://doi.org/10.1021/acs.joc.2c01047
https://doi.org/10.1021/acs.joc.2c01047
Autor:
Caterina Dallari, Claudia Capitini, Martino Calamai, Andrea Trabocchi, Francesco Saverio Pavone, Caterina Credi
Publikováno v:
Nanomaterials, Vol 11, Iss 3, p 665 (2021)
Gold nanoparticles (AuNPs) show physicochemical and optical functionalities that are of great interest for spectroscopy-based detection techniques, and especially for surface enhanced Raman spectroscopy (SERS), which is capable of providing detailed
Externí odkaz:
https://doaj.org/article/33a79ead273448299568a4e410bf3876
Autor:
Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J. H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean-Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu-Taka Azuma, Laura Cerchia, Mariana Spetea, Giangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A. R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A. C. Gomes, Rita C. Guedes, Jean-Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 25, Iss 13, p 2968 (2020)
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Externí odkaz:
https://doaj.org/article/d1b45d5624194ce7bc35f0b2a26b0ee6
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Diversity-Oriented Synthesis (DOS) consists of generating structurally diverse compounds from a complexity-generating reaction followed by cyclization steps and appendage diversity. DOS has gathered interest to systematically explore the chemical spa
Externí odkaz:
https://doaj.org/article/77f07262dea644a6ab54dba2e1eba7c3