Zobrazeno 1 - 3
of 3
pro vyhledávání: '"and Alexey Margolin"'
Autor:
Lee Brettman, Alexey Margolin, Craig B. Langman, Danica Grujic, Jennifer Nezzer, Rita Pease, Linda Easter
Publikováno v:
American Journal of Nephrology. 44:150-158
Background: Hyperoxaluria may result from increased endogenous production or overabsorption of dietary oxalate in the gastrointestinal tract leading to nephrolithiasis and, in some, to oxalate nephropathy and chronic kidney disease. ALLN-177 is an or
Autor:
Neal J. Fetner, Robert J. Cregge, Mark E. Webster, and Mark A. Nitz, Michael A. DesJardin, David W. Freund, David W. Burkhouse, Hoops John F, Richard E. Donaldson, Robert C. Clouse, Stephen W. Horgan, Gerald P. Heinrich, Daniel R. Henton, J. Russell McConnell, Robert T. Keaten, Christian T. Goralski, Kathy P. Barton, Michael E. LeTourneau, and Alexey Margolin, Sandra K. Stolz-Dunn
Publikováno v:
Organic Process Research & Development. 3:241-247
MDL 28,726 is a key intermediate in the synthesis of the ACE inhibitors MDL 27,210A and MDL 100,240. An efficient nine-step synthesis of this tricyclic acid, which has three chiral centers, was developed beginning with 3,4-dihydro-2H-pyran. A key ste
Autor:
Danica Grujic, Bhami C. Shenoy, Saraswathi Mandapati, Chu W. Jung, Margaret Ellen Mcgrath, Reena Patel, Craig B. Langman, Aftab Rashid, Eduardo Salido, Alexey Margolin
Publikováno v:
American journal of nephrology. 29(2)
Background/Aims: Hyperoxaluria is a major risk factor for recurrent urolithiasis and nephrocalcinosis. We tested an oral therapy with a crystalline, cross-linked formulation of oxalate-decarboxylase (OxDc-CLEC®) on the reduction of urinary oxalate a