Zobrazeno 1 - 10
of 55
pro vyhledávání: '"and Alastair J. Barr"'
Autor:
Timo Vögtle, Sumana Sharma, Jun Mori, Zoltan Nagy, Daniela Semeniak, Cyril Scandola, Mitchell J Geer, Christopher W Smith, Jordan Lane, Scott Pollack, Riitta Lassila, Annukka Jouppila, Alastair J Barr, Derek J Ogg, Tina D Howard, Helen J McMiken, Juli Warwicker, Catherine Geh, Rachel Rowlinson, W Mark Abbott, Anita Eckly, Harald Schulze, Gavin J Wright, Alexandra Mazharian, Klaus Fütterer, Sundaresan Rajesh, Michael R Douglas, Yotis A Senis
Publikováno v:
eLife, Vol 8 (2019)
The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and activation. Loss of G6b-B results in severe macrothrombocytopenia, myelofibrosis and aberrant platelet function in mice and hu
Externí odkaz:
https://doaj.org/article/c344e049fe504f759f1164a922d96039
Autor:
Olga Dorofejeva, Alastair J Barr
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184574 (2017)
Receptor-type protein tyrosine phosphatases (RPTPs) of the R3 subgroup play key roles in the immune, vascular and nervous systems. They are characterised by a large ectodomain comprising multiple FNIII-like repeats, a transmembrane domain, and a sing
Externí odkaz:
https://doaj.org/article/2cf09de1eed14cd48105acd079156ac6
Autor:
Yotis A. Senis, Alastair J. Barr
Publikováno v:
Molecules, Vol 23, Iss 3, p 569 (2018)
Protein tyrosine phosphatases (PTPs), of the receptor and non-receptor classes, are key signaling molecules that play critical roles in cellular regulation underlying diverse physiological events. Aberrant signaling as a result of genetic mutation or
Externí odkaz:
https://doaj.org/article/4a238aa37f8c45ec9ee9198141cef965
Autor:
Marie-Claude Gingras, Yu Ling Zhang, Dmitri Kharitidi, Alastair J Barr, Stefan Knapp, Michel L Tremblay, Arnim Pause
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5105 (2009)
The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP). To date, no HD-PTP phosphorylated substrate has been identifi
Externí odkaz:
https://doaj.org/article/4f01f26b78f14bcbb0b50fa1bb020ac0
Autor:
Rachel Rowlinson, Alastair J. Barr, Scott Pollack, Juli Warwicker, Jordan Lane, Alexandra Mazharian, Riitta Lassila, Klaus Fütterer, Harald Schulze, Annukka Jouppila, Christopher W Smith, Yotis A. Senis, Mitchell J. Geer, Gavin J. Wright, Jun Mori, Helen J McMiken, Derek Ogg, Daniela Semeniak, Zoltan Nagy, Michael R. Douglas, Cyril Scandola, Timo Vögtle, Anita Eckly, Tina Howard, Sundaresan Rajesh, Catherine Geh, W Mark Abbott, Sumana Sharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6d88bbd9eb7d2bcf4e273f3cb396ce
https://doi.org/10.7554/elife.46840.060
https://doi.org/10.7554/elife.46840.060
Autor:
Michael Overduin, Alastair J. Barr
Publikováno v:
Journal of visualized experiments : JoVE. (148)
Protein-protein interactions (PPIs) are fundamental to the generation of biological effects. Many are intimately linked with disease, and they are increasingly recognized as offering important targets for drug action1. Numerous techniques are availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3c715d98a37dcefc483f926a375665
https://pubmed.ncbi.nlm.nih.gov/31219457
https://pubmed.ncbi.nlm.nih.gov/31219457
Autor:
W Mark Abbott, Gavin J. Wright, Alexandra Mazharian, Cyril Scandola, Daniela Semeniak, Christopher W Smith, Juli Warwicker, Yotis A. Senis, Mitchell J. Geer, Catherine Geh, Sundaresan Rajesh, Derek Ogg, Rachel Rowlinson, Jordan Lane, Klaus Fütterer, Anita Eckly, Annukka Jouppila, Michael R. Douglas, Harald Schulze, Zoltan Nagy, Timo Vögtle, Scott Pollack, Helen J McMiken, Alastair J. Barr, Riitta Lassila, Jun Mori, Sumana Sharma, Tina Howard
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and activation, loss of which results in severe macrothrombocytopenia and aberrant platelet function in mice and humans. Using a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b619476bd12bcfa38e3e25257108958
Autor:
Alastair J. Barr
Publikováno v:
Essays in Biochemistry
This article gives the reader an insight into the role of biochemistry in some of the current global health and disease problems. It surveys the biochemical causes of disease in an accessible and succinct form while also bringing in aspects of pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1b4eb13ad77d58aec4413af45d0017
https://pubmed.ncbi.nlm.nih.gov/30509933
https://pubmed.ncbi.nlm.nih.gov/30509933
Autor:
Alastair J. Barr, Yotis A. Senis
Publikováno v:
Molecules, Vol 23, Iss 3, p 569 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Protein tyrosine phosphatases (PTPs), of the receptor and non-receptor classes, are key signaling molecules that play critical roles in cellular regulation underlying diverse physiological events. Aberrant signaling as a result of genetic mutation or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9fe206defa15a8a72bbb5c4be56f2a
http://www.mdpi.com/1420-3049/23/3/569
http://www.mdpi.com/1420-3049/23/3/569