Zobrazeno 1 - 10
of 159
pro vyhledávání: '"and Alan Grossfield"'
Autor:
John O. Onukwufor, M. Arsalan Farooqi, Anežka Vodičková, Shon A. Koren, Aksana Baldzizhar, Brandon J. Berry, Gisela Beutner, George A. Porter, Vsevolod Belousov, Alan Grossfield, Andrew P. Wojtovich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Mitochondria regulate diverse cellular signalling processes in addition to producing energy. Here, the authors show a mitochondrial redox switch that, when activated, helps nematode worms sense conditions of low environmental oxygen.
Externí odkaz:
https://doaj.org/article/0ca5eb3f762f416595118bd779d947f4
Autor:
Benjamin Gaston, Santhosh M. Baby, Walter J. May, Alex P. Young, Alan Grossfield, James N. Bates, James M. Seckler, Christopher G. Wilson, Stephen J. Lewis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract We have identified thiolesters that reverse the negative effects of opioids on breathing without compromising antinociception. Here we report the effects of d-cystine diethyl ester (d-cystine diEE) or d-cystine dimethyl ester (d-cystine diME
Externí odkaz:
https://doaj.org/article/41ace98fd93a40d48fca5e4e1a53a813
Autor:
Paulina M. Getsy, Santhosh M. Baby, Ryan B. Gruber, Benjamin Gaston, Tristan H. J. Lewis, Alan Grossfield, James M. Seckler, Yee-Hsee Hsieh, James N. Bates, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Endogenous and exogenously administered S-nitrosothiols modulate the activities of central and peripheral systems that control breathing. We have unpublished data showing that the deleterious effects of morphine on arterial blood-gas chemistry (i.e.,
Externí odkaz:
https://doaj.org/article/917a88664b534ff3bbaeda91c4bb6f4b
Autor:
Ashlin J. Poruthoor, Alan Grossfield
Publikováno v:
bioRxiv
Liquid-liquid phase separation (LLPS) inside the cell often results in biological condensates that can critically impact cell homeostasis. Such phase separation events occur in multiple parts of cells, including the cell membranes, where the so-calle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bac6fc578a0ac63d504cdcd9d228a98
https://europepmc.org/articles/PMC9915641/
https://europepmc.org/articles/PMC9915641/
Publikováno v:
Biophysical Journal. 122:85a-86a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::672c948cdcf05a04c08630ba95a20908
https://doi.org/10.1016/j.bpj.2022.11.665
https://doi.org/10.1016/j.bpj.2022.11.665
Autor:
Paulina M. Getsy, Alex P. Young, James N. Bates, Santhosh M. Baby, James M. Seckler, Alan Grossfield, Yee-Hsee Hsieh, Tristan H.J. Lewis, Michael W. Jenkins, Benjamin Gaston, Stephen J. Lewis
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 153
S-nitrosothiols exert multiple effects on neural processes in the central and peripheral nervous system. This study shows that intravenous infusion of S-nitroso-L-cysteine (SNO-L-CYS, 1 μmol/kg/min) in anesthetized male Sprague Dawley rats elicits (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a2cc4fbf92c472d96bfc02b005cfc1
https://pubmed.ncbi.nlm.nih.gov/36076552
https://pubmed.ncbi.nlm.nih.gov/36076552
Publikováno v:
Proteins
1.AbstractArrestins are important scaffolding proteins that are expressed in all vertebrate animals. They regulate cell signaling events upon binding to active G-protein coupled receptors (GPCR) and trigger endocytosis of active GPCRs. While many of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4193c8797e07cfa8eeb231a3ae0903b3
https://doi.org/10.22541/au.165331624.44817659/v1
https://doi.org/10.22541/au.165331624.44817659/v1
Autor:
Alan Grossfield
Publikováno v:
Living J Comput Mol Sci
Software is ubiquitous in modern science - almost any project, in almost any discipline, requires some code to work. However, many (or even most) scientists are not programmers, and must rely on programs written and maintained by others. A crucial bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd8625af03f632f2f5a8ef70b86fbba
https://doi.org/10.33011/livecoms.3.1.1473
https://doi.org/10.33011/livecoms.3.1.1473
Autor:
Michael F. Brown, Thomas D. Grant, Suchithranga M.D.C. Perera, Leslie Salas-Estrada, Andrey V. Struts, Konstantinos Karpos, Udeep Chawla, Steven D.E. Fried, C. Swathi K. Menon, Nipuna Weerasinghe, Domingo Meza, Derek Mendez, Alan Grossfield, Petra Fromme, Richard A. Kirian
Publikováno v:
Biophysical Journal. 122:199a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb9381eb3c39392f6df90d41d714f03
https://doi.org/10.1016/j.bpj.2022.11.1208
https://doi.org/10.1016/j.bpj.2022.11.1208
Autor:
C. Swathi K. Menon, Konstantinos Karpos, Thomas D. Grant, Andrey V. Struts, Steven D.E. Fried, Suchithranga M.D.C. Perera, Irina V. Kosheleva, Leslie Salas-Estrada, Alan Grossfield, Petra Fromme, Richard A. Kirian, Michael F. Brown
Publikováno v:
Biophysical Journal. 122:191a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55adce0713aa592eb6aa7db6ab6c7da6
https://doi.org/10.1016/j.bpj.2022.11.1170
https://doi.org/10.1016/j.bpj.2022.11.1170