Zobrazeno 1 - 10
of 54
pro vyhledávání: '"and Alan F. Wahl"'
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
PC3 cells stably expressing different levels of MSLN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fe02840c673483123e5f0929841c42
https://doi.org/10.1158/2326-6066.22542501.v1
https://doi.org/10.1158/2326-6066.22542501.v1
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Binding and ADCC function of ABBV-428
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9da41c9d605d96ef019aa9bd2b824b
https://doi.org/10.1158/2326-6066.22542513
https://doi.org/10.1158/2326-6066.22542513
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Liver inflammation and macrophage activation by LB-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c560b9acc52dfa675f6edba71ae0b8
https://doi.org/10.1158/2326-6066.22542507.v1
https://doi.org/10.1158/2326-6066.22542507.v1
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Binding affinity of LB-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba6cdbda7ccf3457705f52ec15cef87
https://doi.org/10.1158/2326-6066.22542498
https://doi.org/10.1158/2326-6066.22542498
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Agonistic CD40 monoclonal antibodies (mAb) have demonstrated some clinical activity, but with dose-limiting toxicity. To reduce systemic toxicity, we developed a bispecific molecule that was maximally active in the presence of a tumor antigen and had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694bf4988a8ed4f7c7f07adbc8095610
https://doi.org/10.1158/2326-6066.c.6549954.v1
https://doi.org/10.1158/2326-6066.c.6549954.v1
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Effect of LB-1 in tumor model without MSLN expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f667aa8a508e86cba85ff56fe10b1c8
https://doi.org/10.1158/2326-6066.22542504
https://doi.org/10.1158/2326-6066.22542504
Autor:
Debra T. Chao, Diane Hollenbaugh, Patricia Culp, Alan F. Wahl, Yuni Fang, Catherine Zhang, John Harlan, Danying Song, Marc Lake, Jean Cabel, Ramesh Iyer, Han Kim, Yoshiko Akamatsu, Mien Sho, Siu Sze Tan, Donghee Choi, Nicole A. Belmar, Diane Cohen, Shiming Ye
Soluble and cell surface expressed MSLN in 4T1-MSLN model and combination treatment with anti-CD40 and anti-MSLN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0253840a13016fee2fe1dd072b9260
https://doi.org/10.1158/2326-6066.22542510.v1
https://doi.org/10.1158/2326-6066.22542510.v1
Autor:
Catherine Zhang, Yoshiko Akamatsu, Alan F. Wahl, Han Kim, Ramesh Iyer, Jeanne M Cabel, Mien Sho, Nicole A. Belmar, Shiming Ye, Patricia Culp, Debra Chao, Marc R. Lake, Siu sze Tan, Cohen Diane Sau Mun, Yuni Fang, Diane Hollenbaugh, Danying Song, Donghee Choi, John Harlan
Publikováno v:
Cancer Immunology Research. 7:1864-1875
Agonistic CD40 monoclonal antibodies (mAb) have demonstrated some clinical activity, but with dose-limiting toxicity. To reduce systemic toxicity, we developed a bispecific molecule that was maximally active in the presence of a tumor antigen and had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ec3a582b90c7996eb5c7dbafda81db
https://doi.org/10.1158/2326-6066.cir-18-0805
https://doi.org/10.1158/2326-6066.cir-18-0805
Autor:
Alan F. Wahl, Puja Sapra, Nahor Haddish-Berhane, Mauricio Leal, Dhaval K. Shah, Omar Kabbarah, Melissa Schutten, Peter D. Senter, Sara A. Hurvitz
Publikováno v:
Annals of the New York Academy of Sciences. 1321:41-54
Antibody-drug conjugates (ADCs) offer promise as a therapeutic modality that can potentially reduce the toxicities and poor therapeutic indices caused by the lack of specificity of conventional anticancer therapies. ADCs combine the potency of cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9781bdea5fe9dc201f3a9714723dabde
https://doi.org/10.1111/nyas.12499
https://doi.org/10.1111/nyas.12499
Autor:
Brian A. Mendelsohn, and Alan F. Wahl, Ezogelin Oflazoglu, Russell J. Sanderson, Brian E. Toki, Damon L. Meyer, Charles G. Cerveny, Stephen C. Alley, Roger F. Zabinski, Svetlana O. Doronina, Peter D. Senter, Tim D. Bovee
Publikováno v:
Bioconjugate Chemistry. 17:114-124
We have previously shown that antibody-drug conjugates (ADCs) consisting of cAC10 (anti-CD30) linked to the antimitotic agent monomethylauristatin E (MMAE) lead to potent in vitro and in vivo activities against antigen positive tumor models. MMAF is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397fcfeadaeb9ffdf49cc7ceecaceac8
https://doi.org/10.1021/bc0502917
https://doi.org/10.1021/bc0502917