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Autor:
Jill E. Porter, Wolfgang Berthold, and Adrienne Farid, Carol Ann Schaffer, Pascal Bailon, Mary Graves, Marlene W. Modi, Wen Pan, Cheryl Spence, Zhi-Xin Xu, Palleroni Alicia Vallejo, George Ehrlich, Wen-Jian Fung
Publikováno v:
Bioconjugate chemistry. 12(2)
A potent, long-lasting form of interferon alpha-2a mono-pegylated with a 40 kilodalton branched poly(ethylene glycol) was designed, synthesized, and characterized. Mono-pegylated interferon alpha-2a was comprised of four major positional isomers invo