Zobrazeno 1 - 10
of 69
pro vyhledávání: '"anchored multiplex PCR"'
Autor:
Jörg Kumbrink, Melanie-Christin Demes, Jan Jeroch, Andreas Bräuninger, Kristin Hartung, Uwe Gerstenmaier, Ralf Marienfeld, Axel Hillmer, Nadine Bohn, Christina Lehning, Ferdinand Ferch, Peter Wild, Stefan Gattenlöhner, Peter Möller, Frederick Klauschen, Andreas Jung
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Lung cancer is a paradigm for a genetically driven tumor. A variety of drugs were developed targeting specific biomarkers requiring testing for tumor genetic alterations in relevant biomarkers. Different next-generation sequencing technologies are av
Externí odkaz:
https://doaj.org/article/4cb60bd82d3c4b56863f874dcfbdde4b
Autor:
Russell J. Diefenbach, Jenny H. Lee, Ashleigh Stewart, Alexander M. Menzies, Matteo S. Carlino, Robyn P. M. Saw, Jonathan R. Stretch, Georgina V. Long, Richard A. Scolyer, Helen Rizos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Detection of melanoma mutations using circulating tumor DNA (ctDNA) is a potential alternative to using genomic DNA from invasive tissue biopsies. To date, mutations in the GC-rich TERT promoter region, which is commonly mutated in melanoma, have bee
Externí odkaz:
https://doaj.org/article/d421e3d41d064555bbe005a85a89db8a
Autor:
Patrice Desmeules, MD, MSc, Dominique K. Boudreau, MSc, Nathalie Bastien, PhD, Marie-Chloé Boulanger, PhD, Yohan Bossé, PhD, Philippe Joubert, MD, PhD, Christian Couture, MD, MSc
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 2, Pp 100276- (2022)
Introduction: With its expanding list of approved and emerging therapeutic indications, NSCLC is the exemplar tumor type requiring upfront assessment of several biomarkers to guide clinical management. Next-generation sequencing allows identification
Externí odkaz:
https://doaj.org/article/c560105466154866b168332eaa811208
Autor:
Shaham Beg, Rohan Bareja, Kentaro Ohara, Kenneth Wha Eng, David C. Wilkes, David J. Pisapia, Wael Al Zoughbi, Sarah Kudman, Wei Zhang, Rema Rao, Jyothi Manohar, Troy Kane, Michael Sigouros, Jenny Zhaoying Xiang, Francesca Khani, Brian D. Robinson, Bishoy M. Faltas, Cora N. Sternberg, Andrea Sboner, Himisha Beltran, Olivier Elemento, Juan Miguel Mosquera
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100944- (2021)
Background: Frequency of clinically relevant mutations in solid tumors by targeted and whole-exome sequencing is ∼30%. Transcriptome analysis complements detection of actionable gene fusions in advanced cancer patients. Goal of this study was to de
Externí odkaz:
https://doaj.org/article/8726c544cc9845559727803f01fd27f6
Autor:
Dominga Racanelli, Monica Brenca, Davide Baldazzi, Frauke Goeman, Beatrice Casini, Biagio De Angelis, Marika Guercio, Giuseppe Maria Milano, Elena Tamborini, Adele Busico, Gianpaolo Dagrada, Cecilia Garofalo, Chiara Caruso, Antonella Brunello, Ymera Pignochino, Enrico Berrino, Giovanni Grignani, Katia Scotlandi, Alessandro Parra, Claudia Maria Hattinger, Toni Ibrahim, Laura Mercatali, Alessandro De Vita, Maria Vincenza Carriero, Matteo Pallocca, Rossella Loria, Renato Covello, Marta Sbaraglia, Angelo Paolo Dei Tos, Rita Falcioni, Roberta Maestro
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/98e931ed65aa45de9c89e7895cd29173
Autor:
Dominga Racanelli, Monica Brenca, Davide Baldazzi, Frauke Goeman, Beatrice Casini, Biagio De Angelis, Marika Guercio, Giuseppe Maria Milano, Elena Tamborini, Adele Busico, Gianpaolo Dagrada, Cecilia Garofalo, Chiara Caruso, Antonella Brunello, Ymera Pignochino, Enrico Berrino, Giovanni Grignani, Katia Scotlandi, Alessandro Parra, Claudia Maria Hattinger, Toni Ibrahim, Laura Mercatali, Alessandro De Vita, Maria Vincenza Carriero, Matteo Pallocca, Rossella Loria, Renato Covello, Marta Sbaraglia, Angelo Paolo Dei Tos, Rita Falcioni, Roberta Maestro
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
This work describes the set-up of a shared platform among the laboratories of the Alleanza Contro il Cancro (ACC) Italian Research Network for the identification of fusion transcripts in sarcomas by using Next Generation Sequencing (NGS). Different N
Externí odkaz:
https://doaj.org/article/42771f3585be471bbb667c6a6f4be202
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Michael Sigouros, Andrea Sboner, Olivier Elemento, Kenneth Wha Eng, Jyothi Manohar, Francesca Khani, Wael Al Zoughbi, Wei Zhang, Sarah Kudman, Jenny Xiang, Bishoy Faltas, Shaham Beg, David Wilkes, David J. Pisapia, Rema Rao, Cora N. Sternberg, Troy Kane, Himisha Beltran, Kentaro Ohara, Brian D. Robinson, Rohan Bareja, Juan Miguel Mosquera
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100944-(2021)
Translational Oncology
Translational Oncology
Highlights • NGS-based clinical studies have reported detection of clinically relevant alterations in ∼30% of patients. • To increase the detection of potential targets, we integrated whole-exome sequencing with a multiplex PCR-based NGS assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fce8e826e24c2e09c9f4aeefd55d54f
http://www.sciencedirect.com/science/article/pii/S1936523320304368
http://www.sciencedirect.com/science/article/pii/S1936523320304368
Autor:
Béla Kajtár, Ildikó Kocsmár, Gabor Smuk, Tamás Tornóczky, Hans Morreau, Gábor Pajor, Veronika Sárosi, Gábor Lotz, Éva Kocsmár, Karoly Szuhai, László Pajor
Publikováno v:
Lung Cancer, 143, 80-85. ELSEVIER IRELAND LTD
Objectives Targeted therapies in the management of patients with lung cancer provide significantly better outcome compared to chemotherapy. Detection of the anaplastic lymphoma kinase (ALK) gene rearrangement has great predictive value for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa5bd19fe75c6bbbe412c838bb3b3b3
http://hdl.handle.net/1887/3182627
http://hdl.handle.net/1887/3182627
