Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons.

Autor: Kumar, Meenakshi Sundaram^1,2 (AUTHOR), Fowler-Magaw, Megan E.^1,3 (AUTHOR), Kulick, Daniel⁴ (AUTHOR), Boopathy, Sivakumar^1,2 (AUTHOR), Gadd, Del Hayden¹ (AUTHOR), Rotunno, Melissa^1,2 (AUTHOR), Douthwright, Catherine^1,2 (AUTHOR), Golebiowski, Diane^1,5 (AUTHOR), Yusuf, Issa⁶ (AUTHOR), Xu, Zuoshang⁶ (AUTHOR), Brown Jr., Robert H.¹ (AUTHOR), Sena-Esteves, Miguel^1,5 (AUTHOR), O'Neil, Alison L.⁷ (AUTHOR), Bosco, Daryl A.^1,6 (AUTHOR) daryl.bosco@umassmed.edu

Publikováno v: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p16013. 24p.

AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner

Autor: Klickstein, Jacob Aaron, Mukkavalli, Sirisha, Raman, Malavika ^*

Publikováno v: In Journal of Biological Chemistry 18 December 2020 295(51):17672-17683

Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones

Autor: Serlidaki, Despina ^‡, van Waarde, Maria A. W.H. ^‡, Rohland, Lukas ^§, Wentink, Anne S. ^§, Dekker, Suzanne L. ^‡, Kamphuis, Maarten J. ^‡, Boertien, Jeffrey M. ^‡, Brunsting, Jeanette F. ^‡, Nillegoda, Nadinath B. ^{§, ¶}, Bukau, Bernd ^§, Mayer, Matthias P. ^§, Kampinga, Harm H. ^{‡, 1}, Bergink, Steven ^{‡, 2}

Publikováno v: In Journal of Biological Chemistry 22 May 2020 295(21):7301-7316

TNF receptor–associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation

Autor: Semmler, Sabrina ^{a, b, 1}, Gagné, Myriam ^{b, c, 2}, Garg, Pranav ^d, Pickles, Sarah R. ^{b, c}, Baudouin, Charlotte ^{b, e}, Hamon-Keromen, Emeline ^{b, f}, Destroismaisons, Laurie ^b, Khalfallah, Yousra ^{b, g}, Chaineau, Mathilde ^{a, h}, Caron, Elise ^b, Bayne, Andrew N. ⁱ, Trempe, Jean-François ⁱ, Cashman, Neil R. ^j, Star, Alexandra T. ^k, Haqqani, Arsalan S. ^k, Durcan, Thomas M. ^{a, h}, Meiering, Elizabeth M. ^l, Robertson, Janice ^m, Grandvaux, Nathalie ^{b, c}, Plotkin, Steven S. ^d, McBride, Heidi M. ^{a, h}, Vande Velde, Christine ^{b, c, g, 3}

Publikováno v: In Journal of Biological Chemistry 20 March 2020 295(12):3808-3825

Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules

Autor: Hans, Friederike ^‡, Glasebach, Hanna ^§, Kahle, Philipp J. ^{‡, §, 1}

Publikováno v: In Journal of Biological Chemistry 17 January 2020 295(3):673-689