Zobrazeno 1 - 10
of 2 665
pro vyhledávání: '"amyloid protein"'
Publikováno v:
Romanian Journal of Neurology, Vol 23, Iss 2, Pp 148-153 (2024)
Background. Alzheimer's disease is a neurodegenerative disorder that worsens over time as more brain regions are affected and symptoms increase. It usually starts slowly and advances permanently. Ranolazine is a piperazine derivative used as a second
Externí odkaz:
https://doaj.org/article/ca6eaaf7daaa4a80ab863010f4a8b93d
Autor:
Bernardo Bonilauri
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 2, Pp 238-257 (2024)
Iatrogenic amyloidosis results from medical therapeutic interventions, leading to the misfolding and aggregation of proteins into amyloid fibrils or to their direct deposition in different tissues. This review aims to provide a comprehensive overview
Externí odkaz:
https://doaj.org/article/eb2266e96b004ad0a21aa0fd40bf6050
Publikováno v:
Smart Molecules, Vol 2, Iss 2, Pp n/a-n/a (2024)
Abstract Metastable endoperoxides with beta‐amyloid fibrils targeting benzothiazole moieties were designed and synthesized. Singlet oxygen released from these endoperoxides by thermal cycloreversion reaction was shown to cause significant structura
Externí odkaz:
https://doaj.org/article/df0c3f1e99b543af903fcfb88712add7
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Alois Alzheimer described the first patient with Alzheimer’s disease (AD) in 1907 and today AD is the most frequently diagnosed of dementias. AD is a multi-factorial neurodegenerative disorder with familial, life style and comorbidity influences im
Externí odkaz:
https://doaj.org/article/f2748baea5b447edb4b839439515b4d1
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Alpha rhythm slowing is an important electroencephalogram(EEG) feature associated with (AD). This study aims to understand the correlation between alpha band deceleration and molecular changes from the perspective of neural computing. Considering the
Externí odkaz:
https://doaj.org/article/5cdd72417fbe4127928eea405d0c6e17
Autor:
Zhongsheng CHEN, Zhangcheng FEI, Renjun PEI, Congchao QIAO, Zongkui WANG, Shengliang YE, Li MA, Rong ZHANG, Changqing LI, Xi DU, Haijun CAO
Publikováno v:
Zhongguo shuxue zazhi, Vol 36, Iss 5, Pp 396-403 (2023)
Objective To explore the risk of Alzheimer′s disease (AD) transmitted by blood transfusion. Methods There were 10 APP/PS1 mice of 3, 6 and 9 months old, half female and half male, and the cognitive and behavioral abilities of C57 mice of the same a
Externí odkaz:
https://doaj.org/article/4aeb5581fb5b4248b4ac59cd62b5fece
Autor:
Xiaotong Wang, Rui Zhou, Xiaqin Sun, Jun Li, Jinxin Wang, Weihua Yue, Lifang Wang, Hesheng Liu, Yigong Shi, Dai Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract A hallmark of Alzheimer's disease (AD) is the senile plaque, which contains β‐amyloid peptides (Aβ). Ganglioside GM1 is the most common brain ganglioside. However, the mechanism of GM1 in modulating Aβ processing is rarely known. Aβ le
Externí odkaz:
https://doaj.org/article/93404aa7e3f34b29b562184fa4160ed6
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Alzheimer’s disease (AD) is the most common chronic neurodegenerative disease worldwide. It causes cognitive dysfunction, such as aphasia and agnosia, and mental symptoms, such as behavioral abnormalities; all of which place a significant psycholog
Externí odkaz:
https://doaj.org/article/06078da0bebf45d0ad5cd8bed9e3ddbd
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