Zobrazeno 1 - 10
of 477
pro vyhledávání: '"amyloid beta 1‐42"'
Autor:
Olena Lykhmus, Olena Kalashnyk, Maryna Skok, Olena Deryabina, Olena Toporova, Ianina Pokholenko, Oksana Gorbatiuk, Vitalii Kordium
Publikováno v:
Exploration of Neuroscience, Vol 3, Iss 3, Pp 207-218 (2024)
Aim: The aim of this work was to study the effects of extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) on inflammation-impaired cognitive functions and the brain of mice. Methods: Young mice (~3-month-old) and aged mice (~18-mo
Externí odkaz:
https://doaj.org/article/5715096943164e88926d4630b4301cd9
Autor:
Nazib M Seidu, Silke Kern, Simona Sacuiu, Therese Rydberg Sterner, Kaj Blennow, Henrik Zetterberg, Olof Lindberg, Daniel Ferreira, Eric Westman, Anna Zettergren, Ingmar Skoog
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract The relation between cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) and magnetic resonance imaging (MRI) measures is poorly understood in cognitively healthy individuals from the general population. Participants’ (n = 226
Externí odkaz:
https://doaj.org/article/5e86e5af78234c3a820b99d07d4c5f5b
Autor:
Zitianyu Wang, Victoria Lewis, Christiane Stehmann, Shiji Varghese, Matteo Senesi, Amelia McGlade, Laura J. Ellett, James D. Doecke, Dhamidhu Eratne, Dennis Velakoulis, Colin L. Masters, Steven J. Collins, Qiao‐Xin Li
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract Most suspected Creutzfeldt‐Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspecte
Externí odkaz:
https://doaj.org/article/bb39afaf574a49de915fe1b741f84a76
Autor:
Sincihu Y, Lusno MFD, Mulyasari TM, Elias SM, Sudiana IK, Kusumastuti K, Sulistyorini L, Keman S
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 19, Pp 73-83 (2023)
Yudhiakuari Sincihu,1,2,* Muhammad Farid Dimjadi Lusno,2 Tri Marthy Mulyasari,2 Saliza Mohd Elias,3,* I Ketut Sudiana,4,* Kurnia Kusumastuti,4,* Lilis Sulistyorini,5 Soedjajadi Keman5,* 1Faculty of Medicine, Widya Mandala Surabaya
Externí odkaz:
https://doaj.org/article/78d25cd5b5814298aeda04cf4b4ae7ff
Autor:
Maxime Vande Vyver, Louise Daeninck, Gino De Smet, Najat Aourz, Surajit Sahu, Sebastiaan Engelborghs, Kris Pauwels, Dimitri De Bundel, Ilse Smolders
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
ObjectivesEpileptiform activity and seizures are present in patients with Alzheimer’s disease (AD) and genetic animal models of AD. Amyloid beta 1-42 (Aβ1-42) oligomers are thought to be crucial in AD and can cause neuronal hyperexcitability in vi
Externí odkaz:
https://doaj.org/article/a7de553c7f9c43949e643a2a8ca977d2
Autor:
Amelia D. Hines, Stephanie McGrath, Amanda S. Latham, Breonna Kusick, Lisa Mulligan, McKenzie L. Richards, Julie A. Moreno
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Canine cognitive dysfunction (CCD) syndrome is a well-recognized naturally occurring disease in aged dogs, with a remarkably similar disease course, both in its clinical presentation and neuropathological changes, as humans with Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/665191882b2a453aa6a11713bea4adea
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Extracellular aggregation of the amyloid-β 1–42 (Aβ42) peptide is a major hallmark of Alzheimer’s disease (AD), with recent data suggesting that Aβ intermediate oligomers (AβO) are more cytotoxic than mature amyloid fibrils. Understanding how
Externí odkaz:
https://doaj.org/article/e656f11f01d541a6a7c75566c75e2882
Autor:
Xu-Sheng Yan, Zhan-Jun Yang, Jian-Xin Jia, Wei Song, Xin Fang, Zhi-Ping Cai, Dong-Sheng Huo, He Wang
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 649-657 (2019)
Cognitive dysfunction in Alzheimer’s disease is strongly associated with a reduction in synaptic plasticity, which may be induced by oxidative stress. Testosterone is beneficial in learning and memory, although the underlying protective mechanism o
Externí odkaz:
https://doaj.org/article/92ad65725fbe4a83b97159d7b9d03903
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