Zobrazeno 1 - 10
of 60
pro vyhledávání: '"amy lynd"'
Autor:
Amy Lynd, Samuel Gonahasa, Sarah G. Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Penelope A. Hancock, Erin Knight, Grant Dorsey, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Janet Hemingway, Moses R. Kamya, Daniel McDermott, Eric R. Lucas, Martin J. Donnelly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pyrethroid bednets treated with the synergist piperonyl butoxide (PBO) offer the possibility of improved vector control in mosquito populations with metabolic resistance. In 2017–2019, we conducted a large-scale, cluster-randomised trial (
Externí odkaz:
https://doaj.org/article/bfc7826f3d024a8f813aed9eb41abdc3
Autor:
Arjen E. van’t Hof, Amy Lynd, Ambrose Oruni, Ismail Onyige, Harun Njoroge, Enock Matovu, Martin J. Donnelly
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background The effectiveness of long-lasting insecticidal nets (LLINs) are being threatened by growing resistance to pyrethroids. To restore their efficacy, a synergist, piperonyl butoxide (PBO) which inhibits cytochrome P450s has been incorporated i
Externí odkaz:
https://doaj.org/article/52d9dbac34cd475baa3465e5ca181bcc
Publikováno v:
Current Research in Parasitology and Vector-Borne Diseases, Vol 6, Iss , Pp 100227- (2024)
To combat pyrethroid insecticide resistance, there has been widespread distribution of pyrethroid-treated bednets (ITNs) co-impregnated with piperonyl butoxide (PBO), a synergist that inhibits enzyme activity to block metabolic resistance. While PBO
Externí odkaz:
https://doaj.org/article/4fb7d0dd540f4ebe8f6cb8b57bd1c658
Autor:
Penelope A. Hancock, Amy Lynd, Antoinette Wiebe, Maria Devine, John Essandoh, Francis Wat’senga, Emile Z. Manzambi, Fiacre Agossa, Martin J. Donnelly, David Weetman, Catherine L. Moyes
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Resistance in malaria vectors to pyrethroids, the most widely used class of insecticides for malaria vector control, threatens the continued efficacy of vector control tools. Target-site resistance is an important genetic resistan
Externí odkaz:
https://doaj.org/article/09b92898be9740658582eb9d78650f49
Autor:
Ruth M.A. Kouamé, Amy Lynd, Jackson K.I. Kouamé, Laura Vavassori, Kouabénan Abo, Martin J. Donnelly, Constant Edi, Eric Lucas
Publikováno v:
Current Research in Parasitology and Vector-Borne Diseases, Vol 3, Iss , Pp 100117- (2023)
Resistance to pyrethroid and organophosphate insecticides in the malaria vector Anopheles gambiae (s.l.) is conferred by a variety of genetic mutations, including single nucleotide polymorphisms (SNPs) and copy number variants (CNVs). Knowledge of th
Externí odkaz:
https://doaj.org/article/a9b893326c6744e89d25a5c3f109ac4b
Autor:
Henry Ddumba Mawejje, David Weetman, Adrienne Epstein, Amy Lynd, Jimmy Opigo, Catherine Maiteki-Sebuguzi, Jo Lines, Moses R. Kamya, Philip J. Rosenthal, Martin J. Donnelly, Grant Dorsey, Sarah G. Staedke
Publikováno v:
Current Research in Parasitology and Vector-Borne Diseases, Vol 3, Iss , Pp 100106- (2023)
Insecticide resistance threatens recent progress on malaria control in Africa. To characterize pyrethroid resistance in Uganda, Anopheles gambiae (s.s.) and Anopheles arabiensis were analyzed from 11 sites with varied vector control strategies. Mosqu
Externí odkaz:
https://doaj.org/article/72cb35ab2f3e4648b88d3c26feeaec27
Autor:
Frank Mechan, Agaba Katureebe, Violet Tuhaise, Martin Mugote, Ambrose Oruni, Ismail Onyige, Kawesa Bumali, Jonathan Thornton, Kilama Maxwell, Mary Kyohere, Moses R. Kamya, Peter Mutungi, Simon P. Kigozi, Adoke Yeka, Jimmy Opigo, Catherine Maiteki-Sebuguzi, Samuel Gonahasa, Janet Hemingway, Grant Dorsey, Lisa J. Reimer, Sarah G. Staedke, Martin J. Donnelly, Amy Lynd
Publikováno v:
Current Research in Parasitology and Vector-Borne Diseases, Vol 2, Iss , Pp 100092- (2022)
Long-lasting insecticidal nets (LLINs) supplemented with the synergist piperonyl butoxide have been developed in response to growing pyrethroid resistance; however, their durability in the field remains poorly described. A pragmatic cluster-randomise
Externí odkaz:
https://doaj.org/article/7989ed403edc4ffeb7e7c220cbcade72
Autor:
Sarah G. Staedke, Moses R. Kamya, Grant Dorsey, Catherine Maiteki-Sebuguzi, Samuel Gonahasa, Adoke Yeka, Amy Lynd, Jimmy Opigo, Janet Hemingway, Martin J. Donnelly
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Long-lasting insecticidal nets (LLINs) are a key malaria control intervention, but their effectiveness is threatened by resistance to pyrethroid insecticides. Some new LLINs combine pyrethroids with piperonyl butoxide (PBO), a syn
Externí odkaz:
https://doaj.org/article/0a79dfa9f6ee4449898b38b1847114c9
Autor:
Sheila Rugnao, Samuel Gonahasa, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Amy Lynd, Janet Hemingway, Martin J. Donnelly, Grant Dorsey, Moses R. Kamya, Sarah G. Staedke
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Recent reductions in malaria burden have been attributed largely to long-lasting insecticidal nets (LLINs). In March–June 2017, approximately 3 years after a national LLIN distribution campaign, a cross-sectional community surve
Externí odkaz:
https://doaj.org/article/ebbed23fff644f67892c942f6c2bcb80
Autor:
Amy Lynd, Samuel Gonahasa, Sarah G. Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Grant Dorsey, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Janet Hemingway, Moses R. Kamya, Martin J. Donnelly
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Background Long-lasting insecticidal nets (LLINs) are the principal tool for malaria control in Africa and are presently treated with a single class of insecticide; however, increasing levels of insecticide resistance threaten their success.
Externí odkaz:
https://doaj.org/article/130c5ed12eb44a01976ca6a84a934147