Zobrazeno 1 - 10
of 682
pro vyhledávání: '"ampk pathway"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 11137-11160 (2024)
Xinru Hu,1,* Shuang Du,1,* Meng Chen,1 Hao Yang,1 Jia He,1 Lei Zhang,1 Bowen Tan,1 Tao Wu,2 Xi Duan1 1Department of Dermatovenereology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of China; 2De
Externí odkaz:
https://doaj.org/article/18c74bf8baa2425fb3498997808cbfed
Autor:
Zi Yi Wang, Rui Xiang Chen, Ji Fei Wang, Shuo Chen Liu, Xiao Xu, Tao Zhou, Yan An Lan Chen, Yao Dong Zhang, Xiang Cheng Li, Chang Xian Li
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 4, Pp 539-551 (2024)
Background & Aims: Apolipoprotein A-1 (ApoA-1), the main apolipoprotein of high-density lipoprotein, has been well studied in the area of lipid metabolism and cardiovascular diseases. In this project, we clarify the function and mechanism of ApoA-1 i
Externí odkaz:
https://doaj.org/article/6f3b417a42084ea88904aac84a53d36f
Publikováno v:
Journal of Men's Health, Vol 19, Iss 11, Pp 82-89 (2023)
Alcoholic fatty liver disease (AFLD) is a liver illness resulting from excessive alcohol consumption. Esculentoside A (EsA) possesses various properties, including antioxidative and anti-inflammatory capabilities, but its role and mechanism in AFLD h
Externí odkaz:
https://doaj.org/article/838e2b648fdf483c9a9856878d7f8697
Autor:
Chen Lu, Lin Chengmin
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 429-4 (2024)
Diabetic retinopathy (DR), a major complication of diabetes causing blindness, is characterized by retinal damage due to capillary degeneration and vascular leakage. Current treatments are not fully effective, highlighting the need for searching new
Externí odkaz:
https://doaj.org/article/e5b04703dc9847dbb4264dd159645ce7
Autor:
Tan Tan, Zhiyuan Song, Wenya Li, Runming Wang, Mingli Zhu, Zuoxiang Liang, Yilina Bai, Qi Wang, Hanyu Wu, Xiaoxiang Hu, Yiming Xing
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic hepatic disease and results in non-alcoholic steatohepatitis (NASH), which progresses to fibrosis and cirrhosis. Although the Leptin deficient rodent
Externí odkaz:
https://doaj.org/article/0239b45256fb49938c1afeb5a2715ec2
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25458- (2024)
Obesity has a significant impact on endocrine function, which leads to metabolic diseases including diabetes, insulin resistance, and other complications associated with obesity. Development of effective and safe anti-obesity drugs is imperative and
Externí odkaz:
https://doaj.org/article/89fa662a36234c1ab86b5d5c3a9e172c
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
Substantial attention has been paid to the various effects of metformin on liver diseases; the liver is the targeted organ where metformin exerts its antihyperglycemic properties. In non-alcoholic fatty liver disease (NAFLD), studies have shown that
Externí odkaz:
https://doaj.org/article/ebc40a80b19e4eb6aefaa0690ec29d5a
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune cells and other cells respond to nutrient deprivation by the classic catabolic pathway of AMPK (Adenosine monophosphate kinase). This kinase is a pivotal regulator of glucose and fatty acids metabolism, although current evidence highlights its
Externí odkaz:
https://doaj.org/article/37c3ebe8974b474c9c49a9a22de51447
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 285-294 (2023)
Septic cardiomyopathy is associated with mechanisms such as excessive inflammation, oxidative stress, regulation of calcium homeostasis, endothelial dysfunction, mitochondrial dysfunction, and cardiomyocyte death, and there is no effective treatment
Externí odkaz:
https://doaj.org/article/fa657832261c4efb9d826c8a215cb58d
Autor:
Nidhi Sharma, Richa Dhingra
Publikováno v:
Journal of Diabetology, Vol 14, Iss 4, Pp 186-192 (2023)
Diabetes is a prevalent metabolic disorder that results in several comorbidities including cancer. Cancer becomes the most severe complication of diabetes patients. Growing evidence proved that impaired glucose homeostasis is an independent risk fact
Externí odkaz:
https://doaj.org/article/ab3292b9c10945358800aa34984b8f7a