Zobrazeno 1 - 10
of 83
pro vyhledávání: '"aminomethylcycline"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objective In the present study, we aimed to compare the clinical efficacy and safety of omadacycline (OMC) with its comparators for the treatment of complicated skin and soft tissue infections (cSSTIs) in adult patients. Methods Randomized c
Externí odkaz:
https://doaj.org/article/92c50de3a33b4640856c14023147364b
Akademický článek
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Autor:
Meng Xiao, Jing-jing Huang, Ge Zhang, Wen-hang Yang, Fanrong Kong, Timothy Kudinha, Ying-chun Xu
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Omadacycline (ZL-2401) is a semi-synthetic derivative of minocycline. It has a broadspectrum activity against Gram-positive and Gram-negative bacteria, and atypical pathogens. The objective of this study was to evaluate the antiba
Externí odkaz:
https://doaj.org/article/5704c33b3d8d41f88b1937be359626a2
Autor:
Fernando Durães, Emília Sousa
Publikováno v:
Pharmaceuticals, Vol 12, Iss 2, p 63 (2019)
Omadacycline (Nuzyra®) is a new aminomethylcycline, approved by the U. S. Food and Drug Administration in 2018, as a tetracycline antibacterial. It can be used in community-acquired pneumonia and in acute bacterial skin and skin-structure infections
Externí odkaz:
https://doaj.org/article/498d434cd3704c9ca4f61ba934978c31
Autor:
Yingchun Xu, Jing-Jing Huang, Ge Zhang, Wen Hang Yang, Fanrong Kong, Meng Xiao, Timothy Kudinha
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Microbiology
BMC Microbiology
BackgroundOmadacycline (ZL-2401) is a semi-synthetic derivative of minocycline. It has a broadspectrum activity against Gram-positive and Gram-negative bacteria, and atypical pathogens. The objective of this study was to evaluate the antibacterial ac
Autor:
Nabina D Gurung, Qingmei Liu, Michael D. Huband, Jennifer D Thompson, Li Li, Jennifer M. Streit, Jay Zhang, Mariana Castanheira
Publikováno v:
Antimicrobial Agents and Chemotherapy
KBP-7072 is a novel broad-spectrum tetracycline (aminomethylcycline) antibacterial in clinical development (oral and intravenous formulations) for the treatment of acute bacterial skin and skin structure infections, community-acquired bacterial pneum
Autor:
Domenico Fuoco
Publikováno v:
Antibiotics, Vol 1, Iss 1, Pp 1-13 (2012)
By studying the literature about tetracyclines (TCs), it becomes clearly evident that TCs are very dynamic molecules. In some cases, their structure-activity-relationship (SAR) are well known, especially against bacteria, while against other targets,
Externí odkaz:
https://doaj.org/article/a063de36c4164394a088bc27a2df26be
Autor:
Aura Rusu, Emanuela Lorena Buta
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 2085, p 2085 (2021)
Pharmaceutics, Vol 13, Iss 2085, p 2085 (2021)
The tetracycline antibiotic class has acquired new valuable members due to the optimisation of the chemical structure. The first modern tetracycline introduced into therapy was tigecycline, followed by omadacycline, eravacycline, and sarecycline (the
Autor:
Jason C. Gallagher
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
When tetracyclines were introduced in the 1940s, these antibiotics offered a broad spectrum of activity against multiple types of pathogens. However, their utility waned after the selection of tetracycline resistance in the pathogens against which th
Akademický článek
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