Zobrazeno 1 - 10
of 18 610
pro vyhledávání: '"aminoglycoside"'
Autor:
Xinyun Jian, Cheng Wang, Shijuan Wu, Guo Sun, Chuan Huang, Chengbing Qiu, Yuanzheng Liu, Peter F. Leadlay, Dong Liu, Zixin Deng, Fuling Zhou, Yuhui Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4149-4163 (2024)
Aminoglycosides (AGs) are a class of antibiotics with a broad spectrum of activity. However, their use is limited by safety concerns associated with nephrotoxicity and ototoxicity, as well as drug resistance. To address these issues, semi-synthetic a
Externí odkaz:
https://doaj.org/article/3c9d502866b64bac866eccc70201f248
Autor:
Nilofar Saeli, Saghar Jafari-Ramedani, Rashid Ramazanzadeh, Maryam Nazari, Amirhossein Sahebkar, Farzad Khademi
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Aminoglycosides have been a cornerstone of the treatment of nosocomial infections caused by Pseudomonas aeruginosa for over 80 years. However, escalating emergence of resistance poses a significant challenge. Therefore, this study
Externí odkaz:
https://doaj.org/article/67c538ced0ef438e9b6286354536a130
Publikováno v:
International Journal of Mycobacteriology, Vol 13, Iss 2, Pp 197-205 (2024)
Background: Tuberculosis (TB), a global infectious threat, has seen a concerning rise in aminoglycoside-resistant Mycobacterium tuberculosis (M.tb) strains. The potential role of capsule proteins remains largely unexplored. This layer acts as the pri
Externí odkaz:
https://doaj.org/article/4819b680b998485f8527a65563674905
Publikováno v:
Infection and Drug Resistance, Vol Volume 17, Pp 2329-2335 (2024)
Kexin Tong,1,* Huating Luo,1,* Haifeng Dai,2 Wenxiang Huang1 1Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Infectious Diseases, The Fi
Externí odkaz:
https://doaj.org/article/fb526c0da714465f8f3c2993f88535d6
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background Ototoxicity is a major side effect of many broadly used aminoglycoside antibiotics (AGs) and no FDA-approved otoprotective drug is available currently. The zebrafish has recently become a valuable model to investigate AG-induced h
Externí odkaz:
https://doaj.org/article/37808a6963c246a6a15cabfe890f726d
Autor:
Jillian L. Paegelow, Mike J. Schoonover, Jenna M. Young, Lara K. Maxwell, Jared D. Taylor, Lyndi L. Gilliam, Todd C. Holbrook
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1825-1834 (2024)
Abstract Background Pharmacokinetics of amikacin administered IV to neonatal foals are described, but little data are available regarding the plasma concentrations contributed by concurrent intra‐articular (IA) administration. Hypothesis/Objectives
Externí odkaz:
https://doaj.org/article/74ad0f0d975f4c9ea2af2d480e54143b
Autor:
Rauf Shiraliyev, Mehmet A Orman
Publikováno v:
eLife, Vol 13 (2024)
Aminoglycoside antibiotics target ribosomes and are effective against a wide range of bacteria. Here, we demonstrated that knockout strains related to energy metabolism in Escherichia coli showed increased tolerance to aminoglycosides during the mid-
Externí odkaz:
https://doaj.org/article/37a59e52c0e3467a8a7c1945dd02b0c4
Autor:
Satoshi Nishida, Yasuo Ono
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 2, Pp 293-298 (2024)
The occurrence of multidrug-resistant Acinetobacter baumannii (MDRA) has increased rapidly and is associated with severe nosocomial infections. MDRA has emerged in the hospital setting and has evolved into extensively drug-resistant A. baumannii (XDR
Externí odkaz:
https://doaj.org/article/3309704f853d4806baf3c92c2943d5d1
Autor:
Sara Al-janaby, Mayada Shehan
Publikováno v:
مجلة جامعة الانبار للعلوم الصرفة, Vol 17, Iss 2, Pp 5-11 (2023)
Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections throughout the world, including bacteremia in immunocompromised patients, wound and soft tissue infections, hospital-acquired pneumonia, respiratory infections, a
Externí odkaz:
https://doaj.org/article/44f113b565664967b3bc3938ced3b7af
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