Thermophilic Filamentous Fungus C1-Cell-Cloned SARS-CoV-2-Spike-RBD-Subunit-Vaccine Adjuvanted with Aldydrogel®85 Protects K18-hACE2 Mice against Lethal Virus Challenge

Autor: Ram Nechooshtan, Sharon Ehrlich, Marika Vitikainen, Arik Makovitzki, Eyal Dor, Hadar Marcus, Idan Hefetz, Shani Pitel, Marilyn Wiebe, Anne Huuskonen, Lilach Cherry, Edith Lupu, Yehuda Sapir, Tzvi Holtzman, Moshe Aftalion, David Gur, Hadas Tamir, Yfat Yahalom-Ronen, Yuval Ramot, Noam Kronfeld, David Zarling, Anne Vallerga, Ronen Tchelet, Abraham Nyska, Markku Saloheimo, Mark Emalfarb, Yakir Ophir

Publikováno v: Nechooshtan, R, Ehrlich, S, Vitikainen, M, Makovitzki, A, Dor, E, Marcus, H, Hefetz, I, Pitel, S, Wiebe, M, Huuskonen, A, Cherry, L, Lupu, E, Sapir, Y, Holtzman, T, Aftalion, M, Gur, D, Tamir, H, Yahalom-Ronen, Y, Ramot, Y, Kronfeld, N, Zarling, D, Vallerga, A, Tchelet, R, Nyska, A, Saloheimo, M, Emalfarb, M & Ophir, Y 2022, ' Thermophilic Filamentous Fungus C1-Cell-Cloned SARS-CoV-2-Spike-RBD-Subunit-Vaccine Adjuvanted with Aldydrogel ® 85 Protects K18-hACE2 Mice against Lethal Virus Challenge ', Vaccines, vol. 10, no. 12, 2119 . https://doi.org/10.3390/vaccines10122119
Vaccines; Volume 10; Issue 12; Pages: 2119

SARS-CoV-2 is evolving with increased transmission, host range, pathogenicity, and virulence. The original and mutant viruses escape host innate (Interferon) immunity and adaptive (Antibody) immunity, emphasizing unmet needs for high-yield, commercia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18e033dee1cdd46f411ff7f3bcc150a
https://doi.org/10.3390/vaccines10122119