Zobrazeno 1 - 10
of 37
pro vyhledávání: '"alternatives to animal experiments"'
Autor:
Mariana Neves, Antonina Klippert, Fanny Knöspel, Juliane Rudeck, Ailine Stolz, Zsofia Ban, Markus Becker, Kai Diederich, Barbara Grune, Pia Kahnau, Nils Ohnesorge, Johannes Pucher, Gilbert Schönfelder, Bettina Bert, Daniel Butzke
Publikováno v:
Journal of Biomedical Semantics, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Current animal protection laws require replacement of animal experiments with alternative methods, whenever such methods are suitable to reach the intended scientific objective. However, searching for alternative methods in the scientific li
Externí odkaz:
https://doaj.org/article/136f4476ca0443fba702bb7a53358b93
Autor:
Catharine E. Krebs, Kathrin Herrmann
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Laws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the l
Externí odkaz:
https://doaj.org/article/ddcaf7d5ab0145598e42e2b0ed2be34f
Autor:
Toshiaki Ara, Hiroyuki Kitamura
Publikováno v:
Medicines, Vol 10, Iss 11, p 61 (2023)
As an alternative to animal use, computer simulations are useful for predicting pharmacokinetics and cardiovascular activities. For this purpose, we constructed a statistical model to simulate the effects of local anesthetic agents. To train the mode
Externí odkaz:
https://doaj.org/article/714515eac77b497bb87d72fbead6881e
Akademický článek
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Akademický článek
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Publikováno v:
Bulletin of informatics and cybernetics. 53:1-14
Toxicity evaluation of chemical compounds has traditionally relied on animal experiments;however, the demand for non-animal-based prediction methods for toxicology of compounds is increasing worldwide. Our aim was to provide a classification method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5368374bdb92727988b771f76cdd12
https://doi.org/10.5109/4476055
https://doi.org/10.5109/4476055
Autor:
Hoonakker, M E, Verhagen, L M, van der Maas, L, Metz, B, Uittenbogaard, J P, van de Waterbeemd, B, van Els, C A C M, van Eden, W, Hendriksen, C F M, Sloots, A, Han, W G H
Whole cell Bordetella pertussis (wP) vaccines are still used in many countries to protect against the respiratory disease pertussis. The potency of whole-cell pertussis vaccine lots is determined by an intracerebral challenge test (the Kendrick test)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::98ab6dedaaf65627d7ad148ae4fcb389
https://dspace.library.uu.nl/handle/1874/345486
https://dspace.library.uu.nl/handle/1874/345486
Autor:
Putten, C. M.-T. van der
Microglia are the resident macrophages of the central nervous system (CNS). Like other tissue macrophages, microglia have many different functions under physiological as well as pathological conditions. Microglia can contribute to the initiation, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7b32a687a490af58c8847accb86e18eb
https://dspace.library.uu.nl/handle/1874/311666
https://dspace.library.uu.nl/handle/1874/311666
Microglia are the resident macrophages of the central nervous system (CNS). Like other tissue macrophages, microglia have many different functions under physiological as well as pathological conditions. Microglia can contribute to the initiation, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::42befb2b8006c9dc465b7cc559117911
https://hdl.handle.net/1874/311666
https://hdl.handle.net/1874/311666