Výsledky vyhledávání - "alternative to animal testing"

Akademický článek

Antibiotic-induced dysbiosis in the SCIME™ recapitulates microbial community diversity and metabolites modulation of in vivo disease

Autor: Elena Dalle Vedove, Alessia Benvenga, Gianluca Nicolai, Marcella Massimini, Maria Veronica Giordano, Francesco Di Pierro, Benedetta Bachetti

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

Establishing the contextIntestinal dysbiosis is a significant concern among dog owners, and the gut health of pets is an emerging research field. In this context, the Simulator of the Canine Intestinal Microbial Ecosystem (SCIME™) was recently deve

Externí odkaz: https://doaj.org/article/e9ed5086ca49488aa18d0c499af9e8a9

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Akademický článek

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Akademický článek

Fabricating a Novel Three-Dimensional Skin Model Using Silica Nonwoven Fabrics (SNF)

Autor: Mizuki Iijima, Kazutoshi Iijima

Publikováno v: Applied Sciences, Vol 12, Iss 13, p 6537 (2022)

Silica nonwoven fabrics (SNF) prepared using electrospinning have high biocompatibility, thermal stability, and porosity that allows growing three-dimensional culture of cells. In this study, we used SNF to construct a three-dimensional artificial sk

Externí odkaz: https://doaj.org/article/4b8d9b65f0ef447c8beeed256344dc77

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Akademický článek

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Akademický článek

Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets

Autor: Sung-Hyun Kim, So-Hye Hong, Jin Hee Lee, Dong Han Lee, Kikyung Jung, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Jayoung Jeong, Jae-Ho Oh

Publikováno v: Toxics, Vol 9, Iss 3, p 62 (2021)

Graphene nanoplatelets (GNPs) are one of the major types of carbon based nanomaterials that have different industrial and biomedical applications. There is a risk of exposure to GNP material in individuals involved in their large-scale production and

Externí odkaz: https://doaj.org/article/dce8db13bd7d427f9ec0b12e898d523b

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Akademický článek

Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays

Autor: Sung-Hyun Kim, Dong Han Lee, Jin Hee Lee, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Kikyung Jung, Jayoung Jeong, Jae-Ho Oh, Jong Kwon Lee

Publikováno v: Toxics, Vol 8, Iss 4, p 122 (2020)

Carbon nanotubes (CNTs) are one of the major types of nanomaterials that have various industrial and biomedical applications. However, there is a risk of accidental exposure to CNTs in individuals involved in their large-scale production and in indiv

Externí odkaz: https://doaj.org/article/02b88e3d8de24b7db096182c2f87f0aa

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In vitro methodology for medical device material thrombogenicity assessments: A use condition and bioanalytical proof‐of‐concept approach

Autor: Samantha Ubl, Gaurav Girdhar, Arielle A. Anderson, Sebastian Hoffmann, Michael F. Wolf, Hannah N. Jeffers, Jenny Rodriguez‐Fernandez, Sinduja Thinamany, Carrie A. Strief, Courtney E. DeRusha

Publikováno v: Journal of Biomedical Materials Research. Part B, Applied Biomaterials

Device manufacturers and regulatory agencies currently utilize expensive and often inconclusive in vivo vascular implant models to assess implant material thrombogenicity. We report an in vitro thrombogenicity assessment methodology where test materi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67e08491afea24b9f855f19d34425ff
https://doi.org/10.1002/jbm.b.34705

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Elimination of fluconazole during continuous renal replacement therapy. An in vitro assessment

Autor: Tarik Abarou, Pierre Carli, Pascal Houzé, Frédéric J. Baud, Benoit Pilmis, Jean-Herlé Raphalen, Lionel Lamhaut, Vincent Jullien

Publikováno v: International Journal of Artificial Organs
International Journal of Artificial Organs, Wichtig Editore, 2021, 44 (7), pp.453-464. ⟨10.1177/0391398820976144⟩
The International Journal of Artificial Organs
The International Journal of Artificial Organs, 2021, 44 (7), pp.453-464. ⟨10.1177/0391398820976144⟩

Introduction: Continuous renal replacement therapy (CRRT) efficiently eliminates fluconazole. However, the routes of elimination were not clarified. Adsorption of fluconazole by filters is a pending question. We studied the elimination of fluconazole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b51288e2b8dbc8eccd2eb7c2382405
https://hal.inrae.fr/hal-03339579

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